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Review: could Topamax cause Tinnitus?

Summary: Tinnitus could be caused by Topamax, especially for people who are female, 40-49 old, have been taking the drug for < 1 month, also take Aspirin, and have Depression.

We study 22,424 people who have side effects while taking Topamax from FDA and social media. Among them, 137 have Tinnitus. Find out below who they are, when they have Tinnitus and more.

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Topamax

Topamax (latest outcomes from 24,430 users) has active ingredients of topiramate. It is often used in migraine.

Tinnitus

Tinnitus (a ringing in the ears) (latest reports from 112,995 patients) has been reported by people with depression, high blood pressure, osteoporosis, high blood cholesterol, stress and anxiety.

On Apr, 11, 2014: 22,305 people reported to have side effects when taking Topamax. Among them, 137 people (0.61%) have Tinnitus. They amount to 0.12% of all the 112,988 people who have Tinnitus on eHealthMe.

Trend of Tinnitus in Topamax reports

Time on Topamax when people have Tinnitus * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years
Tinnitus30.00%10.00%0.00%20.00%25.00%10.00%5.00%

Gender of people who have Tinnitus when taking Topamax * :

FemaleMale
Tinnitus84.07%15.93%

Age of people who have Tinnitus when taking Topamax * :

0-12-910-1920-2930-3940-4950-5960+
Tinnitus0.00%2.42%3.23%8.87%13.71%30.65%24.19%16.94%

Severity of Tinnitus when taking Topamax ** :

leastmoderateseveremost severe
Tinnitus20.00%10.00%40.00%30.00%

How people recovered from Tinnitus ** :

while on the drugafter off the drugnot yet
Tinnitus0.00%0.00%100.00%

Top conditions involved for these people * :

  1. Depression (24 people, 17.52%)
  2. Migraine prophylaxis (23 people, 16.79%)
  3. Pain (20 people, 14.60%)
  4. Headache (18 people, 13.14%)
  5. Migraine (16 people, 11.68%)

Top co-used drugs for these people * :

  1. Aspirin (17 people, 12.41%)
  2. Synthroid (17 people, 12.41%)
  3. Imitrex (15 people, 10.95%)
  4. Oxycontin (14 people, 10.22%)
  5. Neurontin (13 people, 9.49%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Related topic: Topamax, Tinnitus

You can also:

On eHealthMe, Topamax (topiramate) is often used for migraine. Find out below the conditions Topamax is used for, how effective it is, and any alternative drugs that you can use to treat those same conditions.

What is Topamax used for and how effective is it:

Other drugs that are used to treat the same conditions:

Could it be a symptom from a condition:

Drugs in real world that are associated with:

Could your condition cause it?

Comments from related studies:

  • From this study (2 months ago):

  • I am on Remicade once a month since July 22nd of 2013. Had a great response until I hurt my low back again. Then the back pain just worked it's way right up my spine to the neck. I have had neck fusion one level...several bad discs. A knee replacement, a shoulder reconstruction etc. The numbness and tingling in my left hand and buzzing in my left ear are driving me nuts. A recent hearing exam showed I had nerve problems there as well. Don't know what to think. Had a brain MRI it showed normal. Now thinking a spinal tap in order?

    Reply

  • From this study (5 months ago):

  • Very debilitating, have seen several physicians, MRI. It started with medication changes but the medication has been changed back. No change in tinnitus. It's severity is such that I have resigned myself to my bed for 9-10 months, have lost over 50 pounds; just don't care enough to eat. Seems there is very little hope for this condition. I just can't help but think it's my medication somewhere.

    Reply

    rblong0928 on Dec, 3, 2013:

    I have been on synthroid since I was about 17. I am 48.

    Reply

    rosalie on Dec, 2, 2013:

    i know the feeling do you take levothyroxine or thyroid meds because i think thats what is causing this i can't take it anymore some one needs to help

    Reply

  • From this study (1 year ago):

  • I have been on topiramate taking 25mg per day for the passed 3 months. I have had ringing in my ears since i started taking the drug but recently the ringing has become so loud that i am having great difficulty falling and staying asleep at night. i got my ears check out and they were fine. I am currently off the medication and it has been 5 days and i have see no improvements with the ringing in my ears. is it safe for me to continue this drug and how can i get rid of the ringing?

    Reply

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NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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