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Review: could Topamax cause Weight gain (Weight increased)?





Summary: Weight gain is found among people who take Topamax, especially for people who are female, 40-49 old, have been taking the drug for 2 - 5 years, also take medication Seroquel, and have Depression.

We study 22,552 people who have side effects while taking Topamax from FDA and social media. Among them, 839 have Weight gain. Find out below who they are, when they have Weight gain and more.

You are not alone: join a mobile support group for people who take Topamax and have Weight gain >>>

Topamax

Topamax has active ingredients of topiramate. It is often used in migraine. (latest outcomes from Topamax 24,579 users)

Weight gain

Weight gain has been reported by people with depression, high blood pressure, bipolar disorder, pain, high blood cholesterol.(latest reports from Weight gain 75,856 patients)

On Dec, 13, 2014: 22,552 people reported to have side effects when taking Topamax. Among them, 839 people (3.72%) have Weight Gain.

Trend of Weight gain in Topamax reports

Time on Topamax when people have Weight gain * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years
Weight gain19.32%23.86%9.09%14.77%27.27%3.41%2.27%

Gender of people who have Weight gain when taking Topamax * :

FemaleMale
Weight gain83.19%16.81%

Age of people who have Weight gain when taking Topamax * :

0-12-910-1920-2930-3940-4950-5960+
Weight gain0.67%1.34%4.14%11.76%23.66%30.35%21.26%6.82%

Severity of Weight gain when taking Topamax ** :

leastmoderateseveremost severe
Weight gain2.70%43.24%45.95%8.11%

How people recovered from Weight gain ** :

while on the drugafter off the drugnot yet
Weight gain10.00%30.00%60.00%

Top conditions involved for these people * :

  1. Depression (196 people, 23.36%)
  2. Bipolar disorder (183 people, 21.81%)
  3. Sleep disorder (110 people, 13.11%)
  4. Anxiety (101 people, 12.04%)
  5. Migraine (88 people, 10.49%)

Top co-used drugs for these people * :

  1. Seroquel (251 people, 29.92%)
  2. Zyprexa (153 people, 18.24%)
  3. Klonopin (137 people, 16.33%)
  4. Neurontin (129 people, 15.38%)
  5. Nexium (125 people, 14.90%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you have Weight Gain while taking Topamax?

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  • Can nuvigil (vs adderall) be used simultaneously to help wean off 60mg/day of adderall? (1 answer)
    (Asked by a 34 year old woman who has Muscle Tightness, Muscle Contractions Involuntary, Ptsd, Anxiety, Apprehension, Feeling Uptight, Jitters, Stress, Stress And Anxiety, Tension, Anxiety Disorder, Depression, Bulimia, Exhaustion, Fatigue, Lethargy, Tiredness, Weariness, ADHD, and takes Nuvigil, Prozac, Flexeril, Topamax, Xanax, Adderall 30)
    I have been on Adderall 30mg 2x daily for years!! I've had it lowered to 20mg, I've TRIED to go months without it (when not working) however I feel I've built up a tolerance level to the point that it's not as effective as it once was. My personal life has detoured WAY past anything an ADHD medication can possibly help as far as focusing on NEEDED tasks etc. I end up feeling wrapped up in what I'm doing at the moment that my anxiety increases due to all that I haven't been able to accomplish. I take various medications for various reasons, depression, anxiety, bulimia etc., and for the most part the doses have varied based on circumstances and current need at said time of prescription.. MY FAMILY HAS A HISTORY OF HEART DISEASE, And realizing that I'm already on the highest Adderall dosage scares me (and THEN as I think about it, it makes my heart race!). I've also noticed increased muscle spasms as well as extreme and intense pressure on my jaw (TMJ). MY QUESTION IS: does anyone have any experience LOWERING their Adderall dosage AND adding Nuvigil? The research I've done to date gives me impression that it could help balance out the more extreme effects of Adderall (60mg/day) but that the nuvigil would or could potentially help with the EXTREME exhaustion I feel as Adderall wears off. Some days I just crash, some days I sleep fine and others no matter how hard I tryyyy, I just CAN'T fall asleep, therefore making the next day worse! IDEALLY I'D LIKE TO BE MED FREE, right now I need them, but am hoping maybe I can speak with my doctor to lower Adderall and add Nuvigil to help wean me off the amphetamines as well as lower dosage intake. YES, a lot of the anxiety, sleeplessness and depression are related to current circumstances in my life, however, where I am is not where I want to be or where I'm headed.. Life is a journey, and all my meds have become a part of a journey I never thought I'd find myself taking. I don't want life/meds to define me, or create a me I no longer recognize, because scarily enough that seems to be a common pattern. As I overcome each and every daily obstacle, I also don't want to be "hooked" on my meds or needing "more" to wake up/sleep/function.. I'd like to work on finding a solution towards weaning off my meds NOW, and work my way off slowly, primarily the Adderall. I'm hoping by suggesting to my doctor and showing him my research he may agree (IF ITS EVEN A LOGICAL COMBO, CLEARLY IM NOT A DOCTOR) nuvigil could help me. I've already started taking less of my anti depressants, trazadone and xanax without discussing with doc because he is always busy.. My next appt I want to go in fully prepared with a plan and an overall goal to REDUCE my Adderall dose, but overall, I'm clueless!!! I have no idea what other meds other than nuvigil "could" potentially help if at all. I could be entirely wrong, Anyone with any experience using one vs other or both simultaneously, or anyone with constructive input, PLEASE COMMENT/SHARE!!
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  • Are an increase in appetite & tiredness side effects of the birth control tri-sprintec?
    (Asked by a 23 year old woman who has Weight Gain, Increased Appetite, and takes Tri-sprintec)
    In the past I have taken the birth control Ortho Tri-Cyclen Lo and have never had any problems. I just switched to the generic brand, Tri-sprintec. I have now officially been taking Tri-Sprintec for 2 months. I recently started to notice that my appetite has increased and I've been eating A LOT more than normal; I have definitely started to gain weight. I also have been a lot more tired than usual.
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  • Can mrsa cause chronic intestinal pseudo obstruction?
    (Asked by a 39 year old woman who has Adhesion, Chronic Intestinal Pseudo-obstruction, MRSA Infection, Upper GI And Small Bowel Series, and takes Atropine, Mebeverine Hydrochloride, Lactulose, Diclofenac Sodium And Misoprostol, Topiramate, Morphine, Vancomycin Hcl)
    I had a small bowel obstruction caused by adhesions from an appendectomy carried out 20yrs previously and had grumbling pain ever since but been labelled a malingerer by my family GP until one day at work when I started with terrible tummy ache and sickness like I'd never known, fetching up bile with force. I hated going to hospital after yrs of being called a moaner but after a day of rolling round in pain, temperature of 103 an dehydration, my Mammy insisted we go and I was seen straight away - to my shock I was in theatre within 3hrs with a serious obstruction.
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    Does anyone with a medical background know about this ailment/disease? Does it sound feasible that MRSA or it's treatment could have caused this? I was surgically debrided up to every other day when the vac pac/negative pressure machine and dressings were changed and the doctors told me I lost a great deal of tissue and had a lot of nerve damage due to the infection.
    Any patient perspectives on this illness would also be very much valued in helping me make a decision, moving forward. If all this is going to accomplish is to attach a label to the pain but not actually change anything, after fighting it for 10yrs now, avoiding hospital as much as I can, I really can't see the point of exploratory surgerys and biopsys now when it is known that I have this propensity towards adhesions and a new wound means a potentially new adhesion growth site.
    If it helps, the appendectomy happened when I was 10yrs old, the MRSA when I was 30 and I am now 40.
    Beat Wishes.
    Reply
  • Bisoprolol ,ive gained 56 pounds
    (Asked by a 60 year old man who has Weight Gain)
    i had a triple by pass,and was prescribed bisoprolol.since taking it i have gained 4 stones in weight ,ive tried diets ,exercise nothing takes the weight off ,should i stop the tablets.
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  • Do the side effects of prolia either stop or lessen over the 6 month period between injections?
    (Asked by a 67 year old woman who has Back Pain, Acid Reflux, Fatigue, Abdominal Pain, Osteoarthritis Generalised, Headache - Mixed Tension Migraine, Itching, Weight Gain, Hot Flush, Musculoskeletal Discomfort, Pain - Abdomen, and takes Feraheme, Pantoprazole, Prolia)
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More questions for: Topamax, Weight gain

You may be interested at these reviews (Write a review):

  • Urea urine increased while taking topamax
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    I was on Topamax to lose weight. It worked for me, I lost weight but my blood urea increased. I have to stop taking it.
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    am only taking 50mg and have only been taking it for 4 days(this is the evening of the 4th day)as a preventative for migraine headaches that I have suffered from from 16 years. I have had pins and needles in my hands and feet as well as spontaneous crying fits since day 2 and Major aggression since yesterday. With normally an insurmountable amount of patience with my 1 year old son, I outright yelled at him last night. This is unacceptable. I have never felt such quick and sudden rage over nothing before, well, over anything before.
  • Lyrica varied widely
    (Posted by a 69 year old woman who has Peripheral Neuropathy, Chronic Pain, Bright-red Rash, Swelling Of Ankles, Weight Gain, and takes Lyrica)
    I was prescribed Lyrica for treatment of chronic pain. It was ineffective, but it knocked out the symptoms of interstitial. However, it also caused rapid weight gain (I went from 110 to 130 lbs. in just a few weeks) and my ankles started to swell. The pain doctor advised me to discontinue the drug, but the urologist suggested lowering the dose. I did, and the swelling went down. I weighed myself daily and watched what I ate, and my weight returned to normal within a month. Subsequently, I continued taking the lower dose and had no further problems. Then I developed severe spinal stenosis, and my dosage of Lyrica was increased to six 75 capsules daily, in addition to 480 mg of morphine sulphate. I tolerated the Lyrica well. After surgery, however, my ankles began to swell again, and although I didn't have a problem with weight gain, I developed a bright red rash from ankles to knees. I dropped the dosage of Lyrica to 50 mg twice daily, and had no further side effects. The rash simply disappeared, with no damage to the skin. Following the surgery, I was able to titrate off morphine completely. I continue to take Lyrica twice daily. It doesn't seem to affect pain (I still ache a bit, as I have degenerative changes in all joints) but it does dampen peripheral neuropathy, which I experience both in my toes and balls of my feet. It also dampens the neuropathy in my forehead, where I had four surgeries to remove a malignant melanoma. I have had no side effects other than those mentioned, and find it interesting the I could tolerate a high dosage of Lyrica prior to surgery, but after surgery could not, and that adverse side effects varied not only with the dosage but with my own physical condition. I don't find it to be highly effective in treating neuropathy, but it does still the tingling enough to let me sleep and take my mind off the condition.
  • Seizure disorder med problems (1 response)
    (Posted by a 53 year old woman who has Flaxseed Oil, Daily Vitamin, Dry Heaves, Dizziness, Nausea, Chills, Sinus Headache, Nightmares - Repeated, and takes Ginger, Venlafaxine Hydrochloride, Topiramate, Lamotrigine)
    Velafaxine 150 mg. 1 per day.

    In process of switching from Topiramate 50 mg. 1 pill in morning & one at night (going off of this because of kidney stones) Was on this medication approximately 10 years.

    Lamotrigine 2 25mg pills in morning and 2 - 25 mg. pills at night.

    On the 3rd day of the 2nd week of switching I started the nightmares. I took a one hour nap and had a nightmare that seemed like it went on the entire time. Even if I slept for 20 minutes I had a dream or nightmare. I've sometimes been known to have vivid dreams but never this constant in my entire life. Also, very seldom do I have such terrible dreams. So many in one evening. They are an occasional thing, not an all night long thing.

    Also, I have sinus trouble occasionally. The same day the nightmares began I got a terrible headache behind my one eye and under my eye. I have no drainage yet anyway. Not sure if this is during the start up of this medicine, but if I had known it could cause trouble with sinus I would never have started it.

    I was put on this as a quick back up plan when the medicine we agreed upon - Levetireacetam made me feel drunk feeling and I had to be careful just walking around my homes and steps.
  • Psychosis, weight loss and topamax (1 response)
    (Posted by a 56 year old woman who has Brain Hemorrhage, Anxiety Disorder, Depression, Partial Seizures, and takes Zoloft, Klonopin, Topamax)
    I had a brain hemorrhage in my occipital lobe. It left me with with a partial seizure disorder. The seizures would interrupt my ability to see. I was trying different anti-seizure medication and they all made me more tired and more depressed. My neurologist decided to try topamax. On topamax I began to feel more energetic and started losing weight. For the first time in years I woke up in the morning feeling zippy. I started feeling euphoric sometimes. I started to feel like I was glowing with life. I became so energetic I was like someone in a manic state. My temper got shorter and I began to hallucinate. I started to see angels and/or feel their presence. I live in a big city and there are a lot of people who are pretty mean here and I decided I wasn't going to let any of them push me around. I wasn't diplomatic anymore with anyone. Basically everyone thought I had gone crazy and I guess I had.
    My psychiatrist saw me and told my neurologist to "Get Her Off The Topamax!" After I stopped taking it and was more my normal tired self, my psychiatrist told me that I had been psychotic and that I had scared him. Unfortunately, after I stopped taking topamax I gained back the 30 pounds I had lost and none of my new clothes fit me. My doctors told me that they had never seen Topamax affect anyone the way it had affected me. They said it usually makes people more sedated. Hopefully, sharing my experience with Topamax will be helpful to someone.

More reviews for: Topamax, Weight gain

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