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Review: could Tramadol cause Fatigue?





Summary: Fatigue is found among people who take Tramadol, especially for people who are female, 60+ old, have been taking the drug for < 1 month, also take medication Tramadol hcl, and have Pain.

We study 38,642 people who have side effects while taking Tramadol from FDA and social media. Among them, 2,128 have Fatigue. Find out below who they are, when they have Fatigue and more.

You are not alone: join a mobile support group for people who take Tramadol and have Fatigue >>>

Tramadol

Tramadol has active ingredients of tramadol hydrochloride. It is often used in pain. (view latest outcomes from 41,501 users)

Fatigue

Fatigue (feeling of tiredness) has been reported by people with multiple sclerosis, high blood pressure, depression, rheumatoid arthritis, osteoporosis.(latest reports from Fatigue 198,350 patients)

On Dec, 14, 2014: 38,642 people reported to have side effects when taking Tramadol. Among them, 2,130 people (5.51%) have Fatigue.

Trend of Fatigue in Tramadol reports

Time on Tramadol when people have Fatigue * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years
Fatigue42.99%11.21%10.75%6.07%22.90%4.21%1.87%

Gender of people who have Fatigue when taking Tramadol * :

FemaleMale
Fatigue70.12%29.88%

Age of people who have Fatigue when taking Tramadol * :

0-12-910-1920-2930-3940-4950-5960+
Fatigue0.10%0.10%0.87%3.97%11.92%13.91%19.61%49.52%

Severity of Fatigue when taking Tramadol ** :

leastmoderateseveremost severe
Fatigue0.00%35.48%51.61%12.90%

How people recovered from Fatigue ** :

while on the drugafter off the drugnot yet
Fatigue3.12%18.75%78.12%

Top conditions involved for these people * :

  1. Pain (459 people, 21.55%)
  2. Hypertension (178 people, 8.36%)
  3. Depression (160 people, 7.51%)
  4. Rheumatoid arthritis (142 people, 6.67%)
  5. Renal failure chronic (99 people, 4.65%)

Top co-used drugs for these people * :

  1. Tramadol hcl (1,651 people, 77.51%)
  2. Aspirin (436 people, 20.47%)
  3. Lisinopril (329 people, 15.45%)
  4. Furosemide (324 people, 15.21%)
  5. Tramadol hydrochloride (290 people, 13.62%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you have Fatigue while taking Tramadol?

You are not alone! Join a mobile support group:
- support group for people who take Tramadol and have Fatigue
- support group for people who take Tramadol
- support group for people who have Fatigue

Drugs in real world that are associated with:

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  • Does anyone experience heart palpitations causedby their acid reflux ?
    (Asked by a 59 year old woman who has Osteoarthritis, Photophobia, Silent Migraine, Blepharitis, Atypical Gerd/LPR/Silent Reflux, IBS, Fibromyalgia Syndrome, and takes Tramadol)
    I have had acid reflux/Gerd for 4 years + Was not believed that symptoms were real for a while as had no heartburn and a diagnosis of Fibromyalgia which even now some medics think is imaginary...it's NOT!!! Following a demeester score of 45 ( very high confirmation of acid reflux) and discovery of a large hiatal hernia, ( a classic physical cause of acid reflux) I had hernia repair operation and LINX anti reflux surgery. Throughout the four years a major symptom of my acid reflux were heart palpatations. They started at the same time I started with reflux and cleared up after the surgery. I have been reflux free palpitation free and antacid free for four months. then I was put on Gabapentin for back spasm and the reflux returned along with the palpitations. Medics keep insisting this is just anxiety yet eat a food that gives me reflux also starts the palps which is the indicator of the reflux as I do not have heartburn. Comes on when relaxing and eating watching tv ( no anxiety present) and when I am sleeping peacefully ( no anxiety present) my heart wakes me up and fires off into tachycardia. Recently a doctor has said it is now known that acid reflux irritates the nerves in the solar plexus area and that triggers the palps. Anyone else experienced this? Are there any studies on it at all? Thanks all.
  • I have been having a horrible reaction to tramadol now from the er doctor. what do i do now for pain . i've tried the shots made things even worse. so many trials it's hurts 2 try to gr better ? (2 answers)
    (Asked by a 51 year old woman who takes Tramadol)
    Tramadol so been making me so sick from the ER doctor 2 c my doctor if I can hold on. It's a shame ! So many things they keep trying . It's pain not the knew in thing of treating fibromyalgia. Disk problems nerve sciatic. Anxiety u wouldn't believe. I've talked to the FDA
    I don't feel safe at all anymore and want to get better . My family gets so upset and we all have lives to live but mine has been on hold 4-5yrs. Just to do the simple things then I have to rest. It's sad . I've always been active . And watch out for Savella !! My god all I would like is to fel better. I can't believe all the things I've read about tramadol it makes me mad that an ER doctor gave it to me first and I told doctors and pain management It wsnt helping. Can't sleep anger horrible thoughts.please I can't do those shots they made things even worse and they don't help me.
  • What is the time space for taking l-thyroxine and pantoprazole am dose
    (Asked by a 73 year old woman who has Reflux Gastritis, Tiredness)
    also taking Panioprazole in am forty-five minutes before breakfast,
  • Can nuvigil (vs adderall) be used simultaneously to help wean off 60mg/day of adderall? (1 answer)
    (Asked by a 34 year old woman who has Muscle Tightness, Muscle Contractions Involuntary, Ptsd, Anxiety, Apprehension, Feeling Uptight, Jitters, Stress, Stress And Anxiety, Tension, Anxiety Disorder, Depression, Bulimia, Exhaustion, Fatigue, Lethargy, Tiredness, Weariness, ADHD, and takes Nuvigil, Prozac, Flexeril, Topamax, Xanax, Adderall 30)
    I have been on Adderall 30mg 2x daily for years!! I've had it lowered to 20mg, I've TRIED to go months without it (when not working) however I feel I've built up a tolerance level to the point that it's not as effective as it once was. My personal life has detoured WAY past anything an ADHD medication can possibly help as far as focusing on NEEDED tasks etc. I end up feeling wrapped up in what I'm doing at the moment that my anxiety increases due to all that I haven't been able to accomplish. I take various medications for various reasons, depression, anxiety, bulimia etc., and for the most part the doses have varied based on circumstances and current need at said time of prescription.. MY FAMILY HAS A HISTORY OF HEART DISEASE, And realizing that I'm already on the highest Adderall dosage scares me (and THEN as I think about it, it makes my heart race!). I've also noticed increased muscle spasms as well as extreme and intense pressure on my jaw (TMJ). MY QUESTION IS: does anyone have any experience LOWERING their Adderall dosage AND adding Nuvigil? The research I've done to date gives me impression that it could help balance out the more extreme effects of Adderall (60mg/day) but that the nuvigil would or could potentially help with the EXTREME exhaustion I feel as Adderall wears off. Some days I just crash, some days I sleep fine and others no matter how hard I tryyyy, I just CAN'T fall asleep, therefore making the next day worse! IDEALLY I'D LIKE TO BE MED FREE, right now I need them, but am hoping maybe I can speak with my doctor to lower Adderall and add Nuvigil to help wean me off the amphetamines as well as lower dosage intake. YES, a lot of the anxiety, sleeplessness and depression are related to current circumstances in my life, however, where I am is not where I want to be or where I'm headed.. Life is a journey, and all my meds have become a part of a journey I never thought I'd find myself taking. I don't want life/meds to define me, or create a me I no longer recognize, because scarily enough that seems to be a common pattern. As I overcome each and every daily obstacle, I also don't want to be "hooked" on my meds or needing "more" to wake up/sleep/function.. I'd like to work on finding a solution towards weaning off my meds NOW, and work my way off slowly, primarily the Adderall. I'm hoping by suggesting to my doctor and showing him my research he may agree (IF ITS EVEN A LOGICAL COMBO, CLEARLY IM NOT A DOCTOR) nuvigil could help me. I've already started taking less of my anti depressants, trazadone and xanax without discussing with doc because he is always busy.. My next appt I want to go in fully prepared with a plan and an overall goal to REDUCE my Adderall dose, but overall, I'm clueless!!! I have no idea what other meds other than nuvigil "could" potentially help if at all. I could be entirely wrong, Anyone with any experience using one vs other or both simultaneously, or anyone with constructive input, PLEASE COMMENT/SHARE!!
  • Can you loose weight while taking hydroxyzine?
    (Asked by a 48 year old woman who has Have IC And Noticed Weight Gain While Taking Hydroxyzine, and takes Ultram, Hydroxyzine Pamoate)
    Hydroxyzine has been my life saver but I have noticed a gradual increase in weight. My blood pressure has also gone up. I don't have the increased hunger but what scares me is I am not eating more than I normally do. I do not eat breakfast. I have a Glucerna at lunch and then dinner, protein potatoes/rice and veggies, sometimes pasta nothing huge and a snack at night. Maybe a small bowl of ice cream but not every night. I do not drink soda, lots of water and with dinner a large glass of apple juice. I have noticed every year I put on a little bit more weight. I was tested for my thyroid and it is normal. I haven't started an avid work out program. Doing high intense impact will not work due to my IC. I would like to try power walking. Anyone else experience any of these issues?

More questions for: Tramadol, Fatigue

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  • Diagnosed with postural orthostatic tachycardia syndrome after mirena
    (Posted by a 34 year old woman who has Postural Orthostatic Tachycardia Syndrome, Fatigue, Nausea, Dizzy, and takes Mirena)
    After getting the Mirena put in, I got really sick. I went home and got super dizzy, nauseous, and tired. I felt so sick and could barely function. I called the doctors office and they said it couldn't be from the Mirena. She said that I must have the flu. Well, I kept it in for a little while longer. I then started losing my hair. I went back into my doctors office because they thought I was experiencing the symptoms for the Mirena going through my uterine wall. The ultra sound was fine. She reassured me that the Mirena could not be the cause of my complications. So, a week a later I went to another doctor to have the Mirena taken out.
    Never quite felt like myself and a year later I got diagnosedI with Postural Orthostatic Tachycardia Syndrome, after a tilt table test was performed. It's weird to me that my symptoms started almost immediately after the Mirena was put in.
  • Mucinex dm and advil congetstion
    (Posted by a 58 year old woman who has Blurred Vision, Fatigue, Dizziness)
    I noticed another female with simlar age and side effects; and a third female who in addition was under active thyroid. I have taken both drugs independently and had no problem with them. I am prone to low blood pressure & dizziness due to the thyroid problem
  • No noticeable effects
    (Posted by a 45 year old woman who has Spinal Stenosis, Degenerative Disc Disease, Spondylosis, End Term Osteoarthritis, and takes Red Panax Ginseng, Tramadol )
    No noticeable effects when used together. Tramadol dose 50-100 mg's four times a day.
  • I wish i had never taken ambien
    (Posted by a 43 year old woman who has Fibromyalgia, and takes Savella, Lyrica, Synthroid, Effexor, Tramadol, Duragesic-50, Flexeril, Ambien)
    Ambien was prescribed after my sleep study showed severe sleep latency and awakening. In the five hours I slept I woke 85 times and had only 5 minutes of deep sleep. However, the doctors couldn't make a recommendation because they could detect no cause for the poor sleep pattern. My doctor offered Ambien and since I had obviously needed the help sleeping I took it. For the next 10 years I suffered incredible depression. For example I remember laying in bed staring at the ceiling with tears rolling into my ears but I was too tired to wipe them away and realizing that I wanted to die so badly but there was no way I could have done anything about it. The worst effects were the loss of consciousness and the verbal abuse that I heaped on my husband and son. An example of each : I actually had sex with my husband that I could not remember amd hundreds of other actions and discussions. My husband started asking every morning what I remembered of the night before. He could usually tell when I was Ambien-awake (his name for it) he said my eyes would get glassy and my voice cadence would be off. Unfortunately my oldest son was going from infant to 8 years old at this time and any ifraction or even without provocation I would scream horrible things in his face. I don't remember much of it but what I do remember causes me enormous regret. He went from a happy and active toddler to a terrified amd anxious pre-teen. We are still working through the effects of this behavior. Finally, after a surprise pregnancy (see example above) My baby was placed in NICU and I stayed at the Ronald McDonald House and my son and husband visited when they could. Somehow my Ambien prescription was stopped and so I began going through withdrawal but I had no idea what was going on. My vision became so blurred thqt I couldn't identify items unless they were very large and then only by colors. When I visited my son those several days in the NICU I couldn't walk straight and would try to aim myself toward my goal until I hit a wall and I would correct course. These things didn't bother me at all but the nurses in the NICU were with me nearly the entire day because they were afraid I would have a stroke or who knew. Finally, after discussing these symptoms we decided to gradually stop the medication. Thankfully, i didn't have any withdrawal symptoms then. I did feel like an incredibly heavy and black blanket had been lifted away. Ever since I have had very little trouble with depression despite the continuation of sleep disturbance and pain. On a scale from one to 10 for depression with 10 being committing suicide I think my 10 years on the medicine was probably an 8.5 (I desperately wanted to die) and since stopping the medication I don't think it has gone above a 4 and is usually a 2 or 3. I will spend the rest of my life trying to repair the damage my verbal abuse caused my oldest son and my husband. For 10 years they lived in fear of my rages if I had a bad episode with Ambien.
  • How an integrative wellness approach cured me of insomnia, ibs, and more (1 response)
    (Posted by a 47 year old woman who has Fatigue, Sinusitis Acute, Itching, Cognitive Deterioration, Psoriasis, Anxiety, Restless Leg Syndrome, Frequent Headaches, Nasal Inflammation, Irritable Bowel Syndrome, Chronic Insomnia, and takes Levothyroxine Thyroid, Clonazepam, Ambien Cr)
    For 10+ years, I suffered with insomnia and a host of other problems including intestinal distress, headaches, psoriasis, anxiety, cognitive issues, hypothyroid, chronic itching, restless leg, etc. Traditional medicine, aka taking drugs, was not working to heal me. Since childhood, I’ve had IBS, headaches, and upper respiratory problems. Then, in my early twenties, after childbirth, I begin to suffer with panic attacks. I managed to get the panic attacks under control, but the insomnia never went away. I took both Ambien and Clonazepam at different times in my life. When I expressed my concern over taking these meds, my doctor reassured me and told me that some people just have to take sleeping meds for their entire life. I read literature on insomnia and tried most everything – no late night eating, no TV or electronics before bed, sleep in a cool room with complete darkness, meditate, sleep labs, etc. etc. etc. Even with the sleeping meds, I never got restful sleep. Most days, I felt like it was all I could do just to get by. For at least the first half of each day, I felt that I was in dazed stupor until the meds in me would start to wear off. I was first on Clonazepam and then switched to Ambien. When I made the switch, I suffered through withdrawal for about a week. It was horrible -- no sleep, hallucinations, etc. For years, I had silently suffered – my family, friends, and colleagues having no idea to what extent. I felt that mentally, cognitively, and physically I was slowly slipping away. My love for my child and my desire to nurture and provide for him is what kept me going. Without this purpose in my life, I fear that I might have given up somewhere along the way.

    Finally, a few years ago, I went to see an integrative medicine doctor. After years of being in the darkness, I am finally living again. My IM doctor put me on natural supplements, a natural thyroid replacement, and, most importantly, tested me for food allergies/sensitivities. My test results yielded that I could not tolerate wheat, gluten, yeast, and dairy. I took these results seriously and I completely eliminated these things from my diet. After two weeks of adhering to my new diet, I already felt better. In fact, I felt so much better, that, one evening, I decided not to take my Ambien. I have not taken it or any sleep or anxiety medicine since. My doctor was as surprised as I was and did not really anticipate that the diet alone would cure my insomnia. In fact, he had told me that, since I had been taking sleeping meds for so long, eliminating them completely would be a long process that we would have to work through together. Nearly all of the symptoms I listed have disappeared. I continue to take my natural thyroid replacement and the supplements my doctor suggested. I have the occasional migraine and a few patches of psoriasis -- but nothing like the severity I had before. I am 47 now and I am on a journey of healthy transformation. I eat healthy foods, exercise regularly, and truly feel healthy, younger, and physically stronger than I have in 15 and maybe 20 years. Jokingly, my husband used to refer to me as "fragile." Well, not anymore. In fact, he has told me that my body seems like a completely different one. He has had a front-row seat to my transformation and he is as much "in awe" of the changes in me as I am in myself.

    Ten years ago, I was not optimist about my future. Today, I am full of hope, wonder, energy, and excitement. I believe we have the ability to heal ourselves, but we must be diligent in our pursuit of knowledge, persistent and strong in our will to make lifestyle changes, and patient that results will come as long as we are doing all the right things. By the way, giving up foods I had eaten my entire life was not difficult at all once I did it long enough to realize the tremendous benefits of not eating them.

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