Tramadol and Serotonin syndrome - from FDA reports


Summary

Serotonin syndrome is found among people who take Tramadol, especially for people who are female, 60+ old , have been taking the drug for < 1 month, also take medication Mirtazapine, and have Depression . We study 72,262 people who have side effects while taking Tramadol from FDA. Among them, 986 have Serotonin syndrome. Find out below who they are, when they have Serotonin syndrome and more.

What to expect?

If you take Tramadol and have Serotonin syndrome, find out what symptoms you could have in 1 year or longer.

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Tramadol

Tramadol has active ingredients of tramadol hydrochloride. It is often used in pain. (latest outcomes from Tramadol 77,302 users)

Serotonin Syndrome

Serotonin syndrome (occurs when two drugs that affect the body's level of serotonin are taken together at the same time) has been reported by people with depression, pain, stress and anxiety, major depression, insomnia (latest reports from 9,744 Serotonin syndrome patients).

On Feb, 02, 2017

72,262 people reported to have side effects when taking Tramadol.
Among them, 986 people (1.36%) have Serotonin Syndrome


Number of reports submitted per year:

Could Tramadol cause Serotonin syndrome?

Time on Tramadol when people have Serotonin Syndrome *:

  • < 1 month: 60.92 %
  • 1 - 6 months: 14.94 %
  • 6 - 12 months: 3.45 %
  • 1 - 2 years: 2.3 %
  • 2 - 5 years: 18.39 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Serotonin Syndrome when taking Tramadol *:

  • female: 66.08 %
  • male: 33.92 %

Age of people who have Serotonin Syndrome when taking Tramadol *:

  • 0-1: 0.12 %
  • 2-9: 0.0 %
  • 10-19: 1.2 %
  • 20-29: 10.07 %
  • 30-39: 18.35 %
  • 40-49: 17.39 %
  • 50-59: 18.82 %
  • 60+: 34.05 %

Top conditions involved for these people *:

  • Depression (283 people, 28.70%)
  • Pain (226 people, 22.92%)
  • Analgesic Therapy (76 people, 7.71%)
  • Back Pain (72 people, 7.30%)
  • Fibromyalgia (47 people, 4.77%)

Top co-used drugs for these people *:

  • Mirtazapine (116 people, 11.76%)
  • Diazepam (105 people, 10.65%)
  • Omeprazole (73 people, 7.40%)
  • Cymbalta (71 people, 7.20%)
  • Lorazepam (68 people, 6.90%)

Top other side effects for these people *:

  • Hyperhidrosis (156 people, 15.82%)
  • Arrhythmias (153 people, 15.52%)
  • Tremor (148 people, 15.01%)
  • Agitation (142 people, 14.40%)
  • Confusional State (128 people, 12.98%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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