Review: could Tramadol cause Serotonin syndrome?
Summary: Serotonin syndrome is found among people who take Tramadol, especially for people who are female, 60+ old, have been taking the drug for < 1 month, also take medication Tramadol hcl, and have Depression.
We study 38,699 people who have side effects while taking Tramadol from FDA and social media. Among them, 550 have Serotonin syndrome. Find out below who they are, when they have Serotonin syndrome and more.
You are not alone: join a support group for people who take Tramadol and have Serotonin syndrome >>>
Tramadol has active ingredients of tramadol hydrochloride. It is often used in pain. (latest outcomes from 41,564 Tramadol users)
Serotonin syndrome (occurs when two drugs that affect the body's level of serotonin are taken together at the same time) has been reported by people with depression, pain, stress and anxiety, major depression, bipolar disorder. (latest reports from 6,559 Serotonin syndrome patients)
On Mar, 27, 2015: 38,699 people reported to have side effects when taking Tramadol. Among them, 550 people (1.42%) have Serotonin Syndrome.
Time on Tramadol when people have Serotonin syndrome * :
|< 1 month||1 - 6 months||6 - 12 months||1 - 2 years||2 - 5 years||5 - 10 years||10+ years |
|Serotonin syndrome||54.03%||10.48%||3.23%||3.23%||28.23%||0.81%||0.00% |
Gender of people who have Serotonin syndrome when taking Tramadol * :
|Serotonin syndrome||73.33%||26.67% |
Age of people who have Serotonin syndrome when taking Tramadol * :
|Serotonin syndrome||0.19%||0.00%||0.75%||8.24%||24.53%||20.60%||16.85%||28.84% |
Severity of Serotonin syndrome when taking Tramadol ** :
|least||moderate||severe||most severe |
|Serotonin syndrome||0.00%||50.00%||25.00%||25.00% |
How people recovered from Serotonin syndrome ** :
|while on the drug||after off the drug||not yet |
|Serotonin syndrome||0.00%||33.33%||66.67% |
Top conditions involved for these people * :
- Depression (183 people, 33.27%)
- Pain (97 people, 17.64%)
- Neck pain (50 people, 9.09%)
- Back pain (49 people, 8.91%)
- Psychotic disorder (41 people, 7.45%)
Top co-used drugs for these people * :
- Tramadol hcl (453 people, 82.36%)
- Mirtazapine (120 people, 21.82%)
- Diazepam (112 people, 20.36%)
- Tramadol hydrochloride (99 people, 18.00%)
- Paroxetine hcl (81 people, 14.73%)
* Approximation only. Some reports may have incomplete information.
** Reports from social media are used.
How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.
Get connected: join our support group of Tramadol and serotonin syndrome on
Do you have Serotonin Syndrome while taking Tramadol?
You are not alone! Join a mobile support group on :
- support group for people who take Tramadol and have Serotonin Syndrome
- support group for people who take Tramadol
- support group for people who have Serotonin Syndrome
Drugs in real world that are associated with:
Could your condition cause:
- A study of side effects of Tramadol for a 51-year old woman with Hepatitis B Surface Antigen Positive. The patient has Hot Flashes (sudden feelings of heat)
- A study of drug interactions between Tramadol, Meloxicam, Gabapentin for a 68-year old man with Joint Pain, Tendon Pain. The patient has Dizziness
- A study of side effects of Tramadol for a 87-year old man with Pain. The patient has Baclofen
- A study of drug interactions between Dicyclomine Hydrochloride, Dilaudid, Albuterol, Dronabinol, Cyproheptadine Hydrochloride, Tramadol, Phenergan for a 45-year old woman with Pain - Abdomen, Gerd, Increased Appetite, Nausea, Pain, Nausea And Vomiting. The patient has Nausea And Vomiting
- A study of side effects of Tramadol for a 58-year old man with Arthritis - Osteoarthritis. The patient has Albumin Csf, High Arch (human foot type in which the sole of the foot is distinctly hollow when bearing weight), High Arch (human foot type in which the sole of the foot is distinctly hollow when bearing weight)
Recent Tramadol related drug comparison:
NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.
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