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Review: could Tysabri cause Depression?

Summary: Depression could be caused by Tysabri, especially for people who are female, 40-49 old, have been taking the drug for 2 - 5 years, also take Avonex, and have Multiple sclerosis.

We study 97,520 people who have side effects while taking Tysabri from FDA and social media. Among them, 2,380 have Depression. Find out below who they are, when they have Depression and more.

How are my drugs for patients like me? On eHealthMe, you can research 300 million drug outcomes from FDA and social media. All studies are personalized to gender and age. Start now, it's anonymous, simple & free >>>

Tysabri

Tysabri (latest outcomes from 97,659 users) has active ingredients of natalizumab. It is often used in multiple sclerosis.

Depression

Depression (latest reports from 1,144,306 patients) has been reported by people with quit smoking, multiple sclerosis, pain, pain relief by acupuncture, acupuncture and pain.

On Apr, 3, 2014: 97,502 people reported to have side effects when taking Tysabri. Among them, 2,380 people (2.44%) have Depression. They amount to 0.21% of all the 1,138,489 people who have Depression on eHealthMe.

Trend of Depression in Tysabri reports

Time on Tysabri when people have Depression * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years
Depression9.79%24.27%15.13%22.63%26.88%1.31%0.00%

Gender of people who have Depression when taking Tysabri * :

FemaleMale
Depression76.00%24.00%

Age of people who have Depression when taking Tysabri * :

0-12-910-1920-2930-3940-4950-5960+
Depression0.00%0.00%0.74%6.27%21.71%33.71%27.98%9.59%

Severity of Depression when taking Tysabri ** :

n/a

How people recovered from Depression ** :

n/a

Top conditions involved for these people * :

  1. Multiple sclerosis (2,380 people, 100.00%)
  2. Depression (120 people, 5.04%)
  3. Pain (63 people, 2.65%)
  4. Muscle spasms (56 people, 2.35%)
  5. Fatigue (45 people, 1.89%)

Top co-used drugs for these people * :

  1. Avonex (342 people, 14.37%)
  2. Baclofen (110 people, 4.62%)
  3. Cymbalta (77 people, 3.24%)
  4. Neurontin (61 people, 2.56%)
  5. Ampyra (54 people, 2.27%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Related topic: Tysabri, Depression

You can also:

On eHealthMe, Tysabri (natalizumab) is often used for multiple sclerosis. Find out below the conditions Tysabri is used for, how effective it is, and any alternative drugs that you can use to treat those same conditions.

What is Tysabri used for and how effective is it:

Other drugs that are used to treat the same conditions:

Could it be a symptom from a condition:

Drugs in real world that are associated with:

Could your condition cause it?

Comments from related studies:

  • From this study (17 hours ago):

  • Sarcoidosis caused complete heart block. Pacemaker implanted in December 2009 but for the past two years I have had palpitations caused by around 3.7 million ectopic heartbeats per year.

    Sarcoidosis also in lungs and eyes. Extended use of Pred Forte caused development of cataracts, one of which has been removed and I am awaiting the second operation.

    Breathlessness is caused by lack of oxygen entering the bloodstream and my ongoing heart problems

    Rarely able to sleep properly due to pain, sleeping for about 20 minutes at a time when I become so exhausted that the pain can't keep me awake

    Muscle and joint pain have made me weak and clumsy.Pain is felt all over, from head to toes along with muscle cramps and intense burning sensation to skin on lower legs.

    ACE levels fluctuate but average 110 - 150.

    Blood pressure on average is 150 / 78 - no treatment given

    I also take Nefopam Hydrochloride (Acupan) for pain but this drug is not on the list.

    Immobility, fatigue and constant pain have left me very depressed ad harbouring thoughts of suicide. My 15 year old granddaughter has lived with me since the death of my daughter 11 years ago and it is my hope that I will live long enough to see her settled in college and independent after which the only thing I have to look forward to is to end my own suffering.

    Reply

  • From this study (1 day ago):

  • symptoms seem to have increased since increasing dose of metoprolol and hydralazine

    Reply

  • From this study (5 days ago):

  • There are a few more drugs I'm taking but as of last 3 months I am really suffering my quality of life is low and I do not know what to do

    Reply

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