Review: could Tysabri cause Depression?


Depression is found among people who take Tysabri, especially for people who are female, 40-49 old , have been taking the drug for 2 - 5 years, also take medication Avonex, and have Multiple sclerosis . We study 160,515 people who have side effects while taking Tysabri from FDA and social media. Among them, 3,647 have Depression. Find out below who they are, when they have Depression and more.

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Tysabri has active ingredients of natalizumab. It is often used in multiple sclerosis. (latest outcomes from Tysabri 160,725 users)


Depression has been reported by people with depression, multiple sclerosis, quit smoking, pain (latest reports from 364,584 Depression patients).

On Nov, 29, 2016

160,515 people reported to have side effects when taking Tysabri.
Among them, 3,647 people (2.27%) have Depression

Number of reports submitted per year:

Could Tysabri cause Depression?

Time on Tysabri when people have Depression *:

  • < 1 month: 8.16 %
  • 1 - 6 months: 21.54 %
  • 6 - 12 months: 15.12 %
  • 1 - 2 years: 22.82 %
  • 2 - 5 years: 29.42 %
  • 5 - 10 years: 2.93 %
  • 10+ years: 0.0 %

Gender of people who have Depression when taking Tysabri *:

  • female: 75.71 %
  • male: 24.29 %

Age of people who have Depression when taking Tysabri *:

  • 0-1: 0.1 %
  • 2-9: 0.0 %
  • 10-19: 0.91 %
  • 20-29: 7.26 %
  • 30-39: 21.0 %
  • 40-49: 32.56 %
  • 50-59: 28.33 %
  • 60+: 9.85 %

Top co-used drugs for these people *:

  • Avonex (548 people, 15.03%)
  • Baclofen (126 people, 3.45%)
  • Ampyra (105 people, 2.88%)
  • Accutane (83 people, 2.28%)
  • Cymbalta (79 people, 2.17%)

Forecasts by (We will alert you to new symptoms or undetected conditions when you take Tysabri, learn more)

Potential co-existing symptoms

  • Fatigue (1,008 people, 27.64%)
  • Stress And Anxiety (653 people, 17.91%)
  • Weakness (616 people, 16.89%)
  • Memory Loss (513 people, 14.07%)
  • Headache (492 people, 13.49%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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