Tysabri and Depression - from FDA reports


Summary

Depression is found among people who take Tysabri, especially for people who are female, 40-49 old , have been taking the drug for 2 - 5 years, also take medication Avonex, and have Multiple sclerosis . We study 160,334 people who have side effects while taking Tysabri from FDA. Among them, 3,651 have Depression. Find out below who they are, when they have Depression and more.

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Tysabri

Tysabri has active ingredients of natalizumab. It is often used in multiple sclerosis. (latest outcomes from Tysabri 160,733 users)

Depression

Depression has been reported by people with depression, multiple sclerosis, quit smoking, pain (latest reports from 365,316 Depression patients).

On Jan, 31, 2017

160,334 people reported to have side effects when taking Tysabri.
Among them, 3,651 people (2.28%) have Depression


Number of reports submitted per year:

Could Tysabri cause Depression?

Time on Tysabri when people have Depression *:

  • < 1 month: 8.79 %
  • 1 - 6 months: 22.62 %
  • 6 - 12 months: 14.56 %
  • 1 - 2 years: 22.25 %
  • 2 - 5 years: 28.85 %
  • 5 - 10 years: 2.93 %
  • 10+ years: 0.0 %

Gender of people who have Depression when taking Tysabri *:

  • female: 75.68 %
  • male: 24.32 %

Age of people who have Depression when taking Tysabri *:

  • 0-1: 0.1 %
  • 2-9: 0.0 %
  • 10-19: 0.91 %
  • 20-29: 7.25 %
  • 30-39: 20.97 %
  • 40-49: 32.52 %
  • 50-59: 28.39 %
  • 60+: 9.87 %

Top conditions involved for these people *:

  • Multiple Sclerosis (3,510 people, 96.14%)
  • Pain (81 people, 2.22%)
  • Relapsing-Remitting Multiple Sclerosis (72 people, 1.97%)
  • Acne (72 people, 1.97%)
  • Gait Disturbance (63 people, 1.73%)

Top co-used drugs for these people *:

  • Avonex (548 people, 15.01%)
  • Baclofen (127 people, 3.48%)
  • Ampyra (107 people, 2.93%)
  • Accutane (83 people, 2.27%)
  • Cymbalta (79 people, 2.16%)

Top other side effects for these people *:

  • Fatigue (1,009 people, 27.64%)
  • Stress And Anxiety (653 people, 17.89%)
  • Weakness (617 people, 16.90%)
  • Memory Loss (514 people, 14.08%)
  • Headache (493 people, 13.50%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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