Review: could Tysabri cause Depression?


Summary

Depression is found among people who take Tysabri, especially for people who are female, 40-49 old , have been taking the drug for 2 - 5 years, also take medication Avonex, and have Multiple sclerosis . We study 142,944 people who have side effects while taking Tysabri from FDA and social media. Among them, 3,387 have Depression. Find out below who they are, when they have Depression and more.

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Tysabri

Tysabri has active ingredients of natalizumab. It is often used in multiple sclerosis. (latest outcomes from Tysabri 139,770 users)

Depression

Depression has been reported by people with suicidal ideation, drug ineffective, weakness, insomnia, fatigue (latest reports from 287,165 Depression patients).

On Aug, 30, 2016

142,944 people reported to have side effects when taking Tysabri.
Among them, 3,387 people (2.37%) have Depression


Number of reports submitted per year:

Could Tysabri cause Depression?

Time on Tysabri when people have Depression *:

  • < 1 month: 8.99 %
  • 1 - 6 months: 23.67 %
  • 6 - 12 months: 14.98 %
  • 1 - 2 years: 23.0 %
  • 2 - 5 years: 26.96 %
  • 5 - 10 years: 2.42 %
  • 10+ years: 0.0 %

Gender of people who have Depression when taking Tysabri *:

  • female: 75.84 %
  • male: 24.16 %

Age of people who have Depression when taking Tysabri *:

  • 0-1: 0.11 %
  • 2-9: 0.0 %
  • 10-19: 0.92 %
  • 20-29: 7.19 %
  • 30-39: 20.92 %
  • 40-49: 32.94 %
  • 50-59: 28.14 %
  • 60+: 9.78 %

Top conditions involved for these people *:

  • Multiple Sclerosis (3,280 people, 96.84%)
  • Depression (149 people, 4.40%)
  • Pain (69 people, 2.04%)
  • Relapsing-Remitting Multiple Sclerosis (62 people, 1.83%)
  • Acne (62 people, 1.83%)

Top co-used drugs for these people *:

  • Avonex (528 people, 15.59%)
  • Baclofen (123 people, 3.63%)
  • Cymbalta (73 people, 2.16%)
  • Accutane (73 people, 2.16%)
  • Ampyra (72 people, 2.13%)

Top other side effects for these people *:

  • Fatigue (931 people, 27.49%)
  • Headache (460 people, 13.58%)
  • Multiple Sclerosis Relapse (439 people, 12.96%)
  • Asthenia (408 people, 12.05%)
  • Memory Impairment (406 people, 11.99%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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