Review: could Tysabri cause Progressive Multifocal Leukoencephalopathy?


Summary

Progressive multifocal leukoencephalopathy is found among people who take Tysabri, especially for people who are female, 40-49 old , have been taking the drug for 2 - 5 years, also take medication Baclofen, and have Multiple sclerosis . We study 139,605 people who have side effects while taking Tysabri from FDA and social media. Among them, 3,141 have Progressive multifocal leukoencephalopathy. Find out below who they are, when they have Progressive multifocal leukoencephalopathy and more.

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Tysabri

Tysabri has active ingredients of natalizumab. It is often used in multiple sclerosis. (latest outcomes from Tysabri 139,770 users)

Progressive Multifocal Leukoencephalopathy

Progressive multifocal leukoencephalopathy (rapidly progressive neuromuscular disease caused by opportunistic infection of brain cells) has been reported by people with apraxia, agitation, confusional state, jc virus infection, monoparesis (latest reports from 5,752 Progressive multifocal leukoencephalopathy patients).

On Aug, 27, 2016

139,605 people reported to have side effects when taking Tysabri.
Among them, 3,141 people (2.25%) have Progressive Multifocal Leukoencephalopathy


Number of reports submitted per year:

Could Tysabri cause Progressive multifocal leukoencephalopathy?

Time on Tysabri when people have Progressive Multifocal Leukoencephalopathy *:

  • < 1 month: 1.86 %
  • 1 - 6 months: 3.0 %
  • 6 - 12 months: 4.59 %
  • 1 - 2 years: 16.16 %
  • 2 - 5 years: 69.31 %
  • 5 - 10 years: 5.01 %
  • 10+ years: 0.08 %

Gender of people who have Progressive Multifocal Leukoencephalopathy when taking Tysabri *:

  • female: 68.93 %
  • male: 31.07 %

Age of people who have Progressive Multifocal Leukoencephalopathy when taking Tysabri *:

  • 0-1: 0.07 %
  • 2-9: 0.03 %
  • 10-19: 1.01 %
  • 20-29: 6.24 %
  • 30-39: 22.85 %
  • 40-49: 37.14 %
  • 50-59: 22.26 %
  • 60+: 10.4 %

Severity if Progressive Multifocal Leukoencephalopathy when taking Tysabri **:

  • least: 0.0 %
  • moderate: 0.0 %
  • severe: 0.0 %
  • most severe: 100 %

Top conditions involved for these people *:

  • Multiple Sclerosis (2,252 people)
  • Relapsing-Remitting Multiple Sclerosis (707 people)
  • Depression (171 people)
  • Muscle Spasticity (123 people)
  • Pain (109 people)

Top co-used drugs for these people *:

  • Baclofen (231 people)
  • Lyrica (117 people)
  • Avonex (104 people)
  • Neurontin (96 people)
  • Provigil (83 people)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you have Progressive multifocal leukoencephalopathy when taking Tysabri?

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Progressive multifocal leukoencephalopathy

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NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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