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Review: could Tysabri cause Progressive multifocal leukoencephalopathy?





Summary: Progressive multifocal leukoencephalopathy is found among people who take Tysabri, especially for people who are female, 40-49 old, have been taking the drug for 2 - 5 years, also take medication Baclofen, and have Multiple sclerosis.

We study 97,540 people who have side effects while taking Tysabri from FDA and social media. Among them, 2,943 have Progressive multifocal leukoencephalopathy. Find out below who they are, when they have Progressive multifocal leukoencephalopathy and more.

You are not alone: join a mobile support group for people who take Tysabri and have Progressive multifocal leukoencephalopathy >>>

Tysabri

Tysabri has active ingredients of natalizumab. It is often used in multiple sclerosis. (latest outcomes from Tysabri 97,681 users)

Progressive multifocal leukoencephalopathy

Progressive multifocal leukoencephalopathy (rapidly progressive neuromuscular disease caused by opportunistic infection of brain cells) has been reported by people with multiple sclerosis, relapsing-remitting multiple sclerosis, chronic lymphocytic leukaemia, non-hodgkin's lymphoma, rheumatoid arthritis.(latest reports from Progressive multifocal leukoencephalopathy 5,165 patients)

On Nov, 26, 2014: 97,540 people reported to have side effects when taking Tysabri. Among them, 2,943 people (3.02%) have Progressive Multifocal Leukoencephalopathy.

Trend of Progressive multifocal leukoencephalopathy in Tysabri reports

Time on Tysabri when people have Progressive multifocal leukoencephalopathy * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years
Progressive multifocal leukoencephalopathy2.76%3.48%4.88%15.32%68.96%4.56%0.04%

Gender of people who have Progressive multifocal leukoencephalopathy when taking Tysabri * :

FemaleMale
Progressive multifocal leukoencephalopathy68.23%31.77%

Age of people who have Progressive multifocal leukoencephalopathy when taking Tysabri * :

0-12-910-1920-2930-3940-4950-5960+
Progressive multifocal leukoencephalopathy0.00%0.00%0.74%6.41%23.34%37.93%21.97%9.62%

Severity of Progressive multifocal leukoencephalopathy when taking Tysabri ** :

leastmoderateseveremost severe
Progressive multifocal leukoencephalopathy0.00%0.00%0.00%100.00%

How people recovered from Progressive multifocal leukoencephalopathy ** :

n/a

Top conditions involved for these people * :

  1. Multiple sclerosis (2,186 people, 74.28%)
  2. Relapsing-remitting multiple sclerosis (638 people, 21.68%)
  3. Depression (180 people, 6.12%)
  4. Muscle spasticity (146 people, 4.96%)
  5. Fatigue (99 people, 3.36%)

Top co-used drugs for these people * :

  1. Baclofen (213 people, 7.24%)
  2. Vitamin d (146 people, 4.96%)
  3. Lyrica (108 people, 3.67%)
  4. Provigil (103 people, 3.50%)
  5. Zanaflex (100 people, 3.40%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you have Progressive Multifocal Leukoencephalopathy while taking Tysabri?

You are not alone! Join a mobile support group:
- support group for people who take Tysabri and have Progressive Multifocal Leukoencephalopathy
- support group for people who take Tysabri
- support group for people who have Progressive Multifocal Leukoencephalopathy

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More questions for: Tysabri, Progressive multifocal leukoencephalopathy

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Comments from related drug studies (Check your drugs):

  • I have been on Tysabri continuously for five years. I also tested positive for the JC Virus. My doctor changed my dosing schedule to every six weeks. May was the first month of the new schedule and within two days from the skipped four week dosing, widespread joint pain started and has persisted sin ...
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  • I've had two infusions, after the first one I had a bad headache that was treatable. After the second infusion my body started to ache within hours, about 10 days later I was in bed being told I have the flu. Five days later I am still hurting with the tiredness being intermitten. Spoke to my Neurol ...
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  • I recently went to have Right knee replacement surgery and did not recover well from the anesthesia. I had severe difficulty breathing and low urine output as well as induced CHF from IV fluid challenge to attempt to raise BP. Some of the meds that are specifically administered on a very strict sche ...
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  • Prior to starting this course of prescription medication (particularly gabapentin and Tysabri) I had excellent oral hygiene and excellent dental results to go along with those hygiene habits. In the past few years I have had an alarming increase in the rate of cavities and oral decay, despite my ora ...
    Reply
  • I have been on the Tysabri since June, 2011. I have not seen any physical change in my side effects from my MS, the only positive would be on my last MRI there were no new lesions. The hair loss has started in the past 3-4 months, at first I thought it was seasonal, but after the season change it ...
    Reply

More related studies for: Tysabri, Progressive multifocal leukoencephalopathy

NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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