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Review: could Tysabri cause Pulmonary embolism?

We study 97,537 people who have side effects while taking Tysabri from FDA and social media. Among them, 399 have Pulmonary embolism. Find out below who they are, when they have Pulmonary embolism and more.

Get connected: join a mobile support group for people who take Tysabri and have Pulmonary embolism >>>


Tysabri (latest outcomes from 97,677 users) has active ingredients of natalizumab. It is often used in multiple sclerosis.

Pulmonary embolism

Pulmonary embolism (blockage of the main artery of the lung) (latest reports from 340,215 patients) has been reported by people with birth control, pain, high blood pressure, premenstrual syndrome, acne.

On Sep, 16, 2014: 97,534 people reported to have side effects when taking Tysabri. Among them, 399 people (0.41%) have Pulmonary Embolism.

Trend of Pulmonary embolism in Tysabri reports

Time on Tysabri when people have Pulmonary embolism * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years
Pulmonary embolism11.05%31.40%13.37%20.35%23.84%0.00%0.00%

Gender of people who have Pulmonary embolism when taking Tysabri * :

Pulmonary embolism71.30%28.70%

Age of people who have Pulmonary embolism when taking Tysabri * :

Pulmonary embolism0.00%0.00%0.00%9.27%17.79%35.09%28.32%9.52%

Severity of Pulmonary embolism when taking Tysabri ** :


How people recovered from Pulmonary embolism ** :


Top conditions involved for these people * :

  1. Multiple sclerosis (340 people, 85.21%)
  2. Relapsing-remitting multiple sclerosis (56 people, 14.04%)
  3. Pain (17 people, 4.26%)
  4. Crohn's disease (16 people, 4.01%)
  5. Depression (14 people, 3.51%)

Top co-used drugs for these people * :

  1. Baclofen (57 people, 14.29%)
  2. Avonex (40 people, 10.03%)
  3. Provigil (20 people, 5.01%)
  4. Lyrica (18 people, 4.51%)
  5. Gabapentin (17 people, 4.26%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you have Pulmonary Embolism while taking Tysabri?

Get connected! Join a mobile support group:
- group for people who take Tysabri and have Pulmonary Embolism
- group for people who take Tysabri
- group for people who have Pulmonary Embolism

Comments from related studies:

  • From this study (3 weeks ago):

  • Adrienne on Aug, 12, 2014:

    Hi R,
    I'm responding to your letter in eHealthMe. I was taking Escitalopram - the generic name for Lexapro for about 3 months. In Sept. I slowly took myself off this med. In Dec. 2013 I was admitted to the hospital because of chest pain. A ct scan showed I had developed a Pulmonary Embolism. I was shocked because I was always so healthy. The Hematologist put me on Warfarin since he does not know where the PE came from. The last blood work showed the PE is gone. The Ultra Sound of my legs was negative. I know where the PE came from-taking the generic for Lexapro. I still have to be on Warfarin indefinitely. Thanks for hearing me out. I hope this helps.


    Adrienne on Aug, 12, 2014:

    Hi Gary,
    Just read your letter in eHealthMe. Sounds like me. I was taking Escitalopram-the generic for Lexapro for about three months. I didn't like the way it made me feel. So in Sept. or Oct I slowly took myself off this med. On Dec 23, 2013 I was admitted to the hospital because of chest pain. a ct scan showed I developed a Pulmonary Embolism. An Ultra Sound of my legs came back negative. I am on Warfarin for the PE. My last blood work showed the PE is gone. Since the hematologist does not know where the PE came from I have to be on Warfarin indefinitely. I know where it came from, the drug Lexapro. Thanks for hearing me out. I hope this helps.


    Gary Crockett on Nov, 3, 2011:

    I slowly took myself off Lexapro 10mg over 2 months after 2 months of being off it I have had a pulmonary embolism. I went back to the page of side effects for Lexapro and found pulmonary embolism and deep vein thrombosis listed as a side effect of Lexapro. I am now looking for any others who have had this experience. So far I have survived the embolism but am still in severe pain and looking for answers. I am in Australia.


    R on Sep, 2, 2012:

    I have been taking Lexapro for a little over a year. I was/am anemic but otherwise healthy. June of this year, I started blacking out and found out I had to small blood clots in my lung. My hormones are not right, and have to be on Coumadin. No Doctor mentioned it being a possible side effect of the drug. They still do not have an answer as to what caused it.


  • From this study (2 months ago):

  • I am asking if the cause is from tysabri


  • From this study (3 months ago):

  • have been having severe back pain on lower spine right above tail bone


    Linda on Jun, 9, 2014:

    I reread your symptoms. It is primarily low back pain. It could be osteoarthritis, ankylosing spondylitis, possibly a slipped disc. I take back that it might be hemorrhoids as it sounds too far up. Definitely have it checked out.


    Linda on Jun, 9, 2014:

    Did you fall on coccyx ( tailbone ) ? I had similar symptoms and was diagnosed with Ankylosing Spondylitis, an autoimmune disease that affects the spine by coursing inflammation particularly in the sacral iliac joints which are located in your buttock. The pain can radiate to your back and mine sometimes goes to my hips, pelvis and sometimes down to my knee. I am a 52 year old female from their US. If you fell, you could have broken your coccyx, and that could take up to a year to feel better, ask your MD. Could be hemorrhoids, a polyp or mass and your rectum. You should definitely get it checked out.


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More reviews for: Tysabri, Pulmonary embolism

On eHealthMe, Tysabri (natalizumab) is often used for multiple sclerosis. Find out below the conditions Tysabri is used for, how effective it is, and any alternative drugs that you can use to treat those same conditions.

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