Review: could Valproic Acid cause Headache?


Headache is found among people who take Valproic Acid, especially for people who are female, 40-49 old , have been taking the drug for < 1 month, also take medication Lamotrigine, and have Epilepsy . We study 10,367 people who have side effects while taking Valproic acid from FDA and social media. Among them, 136 have Headache. Find out below who they are, when they have Headache and more.

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Valproic Acid

Valproic acid has active ingredients of valproic acid. It is often used in epilepsy. (latest outcomes from Valproic acid 10,769 users)


Headache (pain in head) has been reported by people with breathing difficulty, pain, drug ineffective, weakness, chest pain (latest reports from 209,297 Headache patients).

On Aug, 26, 2016

10,367 people reported to have side effects when taking Valproic Acid.
Among them, 136 people (1.31%) have Headache

Number of reports submitted per year:

Could Valproic acid cause Headache?

Time on Valproic Acid when people have Headache *:

  • < 1 month: 50.0 %
  • 1 - 6 months: 37.5 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 12.5 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Headache when taking Valproic Acid *:

  • female: 64.62 %
  • male: 35.38 %

Age of people who have Headache when taking Valproic Acid *:

  • 0-1: 0.87 %
  • 2-9: 4.35 %
  • 10-19: 7.83 %
  • 20-29: 24.35 %
  • 30-39: 18.26 %
  • 40-49: 26.09 %
  • 50-59: 7.83 %
  • 60+: 10.43 %

Severity if Headache when taking Valproic Acid **:

  • least: 0.0 %
  • moderate: 100 %
  • severe: 0.0 %
  • most severe: 0.0 %

Top conditions involved for these people *:

  • Epilepsy (32 people)
  • Schizophrenia (13 people)
  • Depression (12 people)
  • Bipolar Disorder (11 people)
  • Convulsion (9 people)

Top co-used drugs for these people *:

  • Lamotrigine (18 people)
  • Seroquel (15 people)
  • Tegretol (14 people)
  • Carbamazepine (14 people)
  • Keppra (12 people)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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