Review: could Valproic Acid cause Hypothyroidism?


Hypothyroidism is found among people who take Valproic Acid, especially for people who are male, 40-49 old also take medication Levothyroxine Sodium, and have Bipolar disorder . We study 10,718 people who have side effects while taking Valproic acid from FDA and social media. Among them, 38 have Hypothyroidism. Find out below who they are, when they have Hypothyroidism and more.

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Valproic Acid

Valproic acid has active ingredients of valproic acid. It is often used in epilepsy. (latest outcomes from Valproic acid 13,817 users)


Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development) has been reported by people with osteoporosis, high blood pressure, hypothyroidism, osteopenia, depression (latest reports from 77,089 Hypothyroidism patients).

On Oct, 09, 2016

10,718 people reported to have side effects when taking Valproic Acid.
Among them, 38 people (0.35%) have Hypothyroidism

Number of reports submitted per year:

Could Valproic acid cause Hypothyroidism?

Gender of people who have Hypothyroidism when taking Valproic Acid *:

  • female: 32.43 %
  • male: 67.57 %

Age of people who have Hypothyroidism when taking Valproic Acid *:

  • 0-1: 12.5 %
  • 2-9: 6.25 %
  • 10-19: 3.12 %
  • 20-29: 12.5 %
  • 30-39: 15.62 %
  • 40-49: 25.0 %
  • 50-59: 12.5 %
  • 60+: 12.5 %

Top conditions involved for these people *:

  • Bipolar Disorder (5 people, 13.16%)
  • Depression (4 people, 10.53%)
  • Schizoaffective Disorder (2 people, 5.26%)
  • Psychotic Disorder (2 people, 5.26%)
  • Non-Accidental Overdose (2 people, 5.26%)

Top co-used drugs for these people *:

  • Levothyroxine Sodium (9 people, 23.68%)
  • Risperidone (8 people, 21.05%)
  • Zocor (6 people, 15.79%)
  • Neurontin (6 people, 15.79%)
  • Lithium Carbonate (6 people, 15.79%)

Top other side effects for these people *:

  • Syncope (6 people, 15.79%)
  • Rhabdomyolysis (6 people, 15.79%)
  • Visual Acuity Reduced (5 people, 13.16%)
  • Oedema Peripheral (5 people, 13.16%)
  • Dyslipidaemia (5 people, 13.16%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

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