Review: could Valproic Acid cause Muscle Twitching?


Muscle twitching is found among people who take Valproic Acid, especially for people who are male, 10-19 old , have been taking the drug for 1 - 6 months, also take medication Levetiracetam, and have Epilepsy . We study 10,367 people who have side effects while taking Valproic acid from FDA and social media. Among them, 32 have Muscle twitching. Find out below who they are, when they have Muscle twitching and more.

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Valproic Acid

Valproic acid has active ingredients of valproic acid. It is often used in epilepsy. (latest outcomes from Valproic acid 10,769 users)

Muscle Twitching

Muscle twitching has been reported by people with breathing difficulty, memory loss, weakness, insomnia, pneumonia (latest reports from 12,378 Muscle twitching patients).

On Aug, 27, 2016

10,367 people reported to have side effects when taking Valproic Acid.
Among them, 32 people (0.31%) have Muscle Twitching

Number of reports submitted per year:

Could Valproic acid cause Muscle twitching?

Time on Valproic Acid when people have Muscle Twitching *:

  • < 1 month: 0.0 %
  • 1 - 6 months: 100 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Muscle Twitching when taking Valproic Acid *:

  • female: 45.16 %
  • male: 54.84 %

Age of people who have Muscle Twitching when taking Valproic Acid *:

  • 0-1: 0.0 %
  • 2-9: 7.41 %
  • 10-19: 29.63 %
  • 20-29: 14.81 %
  • 30-39: 3.7 %
  • 40-49: 3.7 %
  • 50-59: 25.93 %
  • 60+: 14.81 %

Severity if Muscle Twitching when taking Valproic Acid **:

  • least: 0.0 %
  • moderate: 100 %
  • severe: 0.0 %
  • most severe: 0.0 %

How people recovered from Muscle Twitching **:

  • while on drug: 0.0 %
  • after off the drug: 0.0 %
  • not yet: 100 %

Top conditions involved for these people *:

  • Epilepsy (7 people)
  • Complex Partial Seizures (5 people)
  • Schizophrenia (4 people)
  • Drug Exposure During Pregnancy (3 people)
  • Type 2 Diabetes Mellitus (1 person)

Top co-used drugs for these people *:

  • Levetiracetam (8 people)
  • Zonisamide (7 people)
  • Phenytoin (5 people)
  • Paroxetine Hcl (4 people)
  • Carbamazepine (4 people)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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