Review: could Valproic acid cause Muscle twitching?
(By eHealthMe on Mar, 4, 2014)
Severity ratings: 2.0/4
On a scale of 1 to 4: 1=least, 2=moderate, 3=severe, 4=most severe
We study 9,123 people who take Valproic acid. Among them, 29 have Muscle twitching. See who they are, when they have Muscle twitching and more. This review is based on reports from FDA and social media, and is updated regularly.
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Valproic acid (latest outcomes from 9,289 users) has active ingredients of valproic acid. It is often used in epilepsy, bipolar disorder. Commonly reported side effects of Valproic acid include completed suicide, convulsion, fever, drowsiness, fatigue.
Muscle twitching (latest reports from 59,332 patients) has been reported by people with depression, pain, multiple sclerosis, stress and anxiety, high blood pressure.
On Feb, 27, 2014: 8,737 people reported to have side effects when taking Valproic acid. Among them, 29 people (0.33%) have Muscle Twitching.
Time on Valproic acid when people have Muscle twitching * :
|< 1 month||1 - 6 months||6 - 12 months||1 - 2 years||2 - 5 years||5 - 10 years||10+ years |
|Muscle twitching||0.00%||100.00%||0.00%||0.00%||0.00%||0.00%||0.00% |
Gender of people who have Muscle twitching when taking Valproic acid * :
|Muscle twitching||50.00%||50.00% |
Age of people who have Muscle twitching when taking Valproic acid * :
|Muscle twitching||0.00%||7.69%||30.77%||15.38%||3.85%||3.85%||26.92%||11.54% |
Severity of Muscle twitching when taking Valproic acid ** :
|least||moderate||severe||most severe |
|Muscle twitching||0.00%||100.00%||0.00%||0.00% |
How people recovered from Muscle twitching ** :
|while on the drug||after off the drug||not yet |
|Muscle twitching||0.00%||0.00%||100.00% |
Top conditions involved for these people * :
- Epilepsy (7 people, 24.14%)
- Complex partial seizures (5 people, 17.24%)
- Schizophrenia (4 people, 13.79%)
- Drug exposure during pregnancy (3 people, 10.34%)
- Partial seizures (2 people, 6.90%)
Top co-used drugs for these people * :
- Levetiracetam (8 people, 27.59%)
- Zonisamide (7 people, 24.14%)
- Phenytoin (5 people, 17.24%)
- Oxcarbazepine (4 people, 13.79%)
- Carbamazepine (4 people, 13.79%)
* Approximation only. Some reports may have incomplete information.
** Reports from social media are used.
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Related topic: Valproic acid, Muscle twitching
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On eHealthMe, Valproic Acid (valproic acid) is often used for epilepsy. Find out below the conditions Valproic Acid is used for, how effective it is, and any alternative drugs that you can use to treat those same conditions.
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From this study (3 hours ago):
Vyvanse is my most recently prescribed ADD medication, but I have been on various other prescriptions since the age of 9. (Adderall at first for a short time [< 1 month], stopped because it caused severe panic attacks; Concerta in increasing doses over the next 5 years, but never more than 72mg; Vyvanse for the past 3 years, at 60mg for two years, moved up to 70mg last year). Already had trouble falling asleep; when I started taking these stimulants, it became full blown insomnia, requiring prescription of Clonidine (started at .1mg, has increased to .2mg). During the school day all symptoms are managed very well- no trouble focusing, less impulsiveness, more self-control. After Vyvanse wears off (normally seven and a half to eight hours after ingestion), all symptoms of ADD return in full force. A few years ago I was diagnosed with Panic Disorder (without Agoraphobia) when I started getting frequent panic attacks. I was prescribed Hydroxyzine Pamoate 50mg, which I take whenever I feel a panic attack coming on. I had problems with asthma and acid reflux problems since my birth, and the asthma became very severe. I spent much time in the NICU when I was born, and I had to be rushed to the hospital several times in the first few years of my life. I used to carry an inhaler everywhere, but at the age of 10, 3 years after my last major problem with asthma, my physician and I decided that I had successfully overcome my problems with asthma (insofar as one can overcome such problems- in any case, I haven't had a problem with it in nearly a decade. The acid reflux recently returned, but with very low severity. The only problems I've had with it recently are occasionally waking up with feelings of heartburn and acid rising in my chest. My physician told me to take one dose of over-the-counter Pepcid Complete before bed, and that has remedied all problems with the acid reflux. Last year I was diagnosed with Major Depressive Disorder, and prescribed Sertraline.
When I started the ADD stimulants, I had large weight fluctuations, because during the day I had no appetite, but at night I was very hungry. My weight stayed within a range of approximately 40lbs, but there would be months when I gained a lot of weight quickly, and others when I would lose weight just as quickly.
When my workload increased as I began High School, even with a boost in Vyvanse dosage, I found it hard to get all my work done without staying up all night.
I once procrastinated on a project and wound up a week away from the due date with very little done. I stopped taking my Clonidine, and started taking extra Vyvanse and drinking several cups of coffee a day (approx. 10 a day) so I could stay up several nights in a row. After not sleeping from Monday morning to Thursday afternoon, the sleep deprivation resulted in severe bruxism, clicking of my tongue at the back of my teeth uncontrollably, dry mouth, dizziness, rapid heart rate, and eventually auditory hallucinations and syncope. Since then I have not done anything as reckless as abusing stimulants to stay awake.
In times of high stress (the week before opening night for the school musical, for example), I develop an uncontrollable muscle twitch, primarily in my left shoulder but occasionally in my right hand, both at varied and unpredictable intervals. The hand twitch can be very noticeable and very disruptive, especially if it persists for more than a minute. The shoulder twitch is less noticeable, but once acknowledged, it becomes more severe. I have tried holding the limb down, but the only thing that works is riding it out. Never has a single period of muscle twitching exceeded 4 minutes.
From this study (2 weeks ago):
I have tibial prosterior wich causes a lot of pain in my right ankle but recently been having what I think is nerve damage, my question is can this cause nerve damage as it's started in my right foot but now nerve and joint pain has gone to my left foot and my hand and wrists. I have smoked methamphetamine previously and worried this may have caused my nerve pain as after iv used it from lack of sleep ect. my body has all symptoms mentioned above plus more. I have not told my doctor that these symptoms are brought on after drug use& lack of sleep but wanting to know if it could be the reason. I feel it may have done damage because weeks after having methamphetamine I still have slight nerve pain. Does this sound like peripheral neuropathy ? My doctor has prescribed lyrica pregabelin and Celebrex to see if it will relieve my symptoms but after reading more about this drug the side effects sound very severe and unsure weather I should be taking it :(
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