Valproic acid and Hypothyroidism - from FDA reports


Hypothyroidism is found among people who take Valproic acid, especially for people who are male, 40-49 old also take medication Levothyroxine Sodium, and have Depression. This review analyzes which people have Hypothyroidism with Valproic acid. It is created by eHealthMe based on reports of 14,673 people who have side effects when taking Valproic acid from FDA , and is updated regularly.

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On Oct, 03, 2017

14,673 people reported to have side effects when taking Valproic acid.
Among them, 49 people (0.33%) have Hypothyroidism

Number of reports submitted per year:

Could Valproic acid cause Hypothyroidism?

Gender of people who have Hypothyroidism when taking Valproic acid *:

  • female: 31.82 %
  • male: 68.18 %

Age of people who have Hypothyroidism when taking Valproic acid *:

  • 0-1: 10.53 %
  • 2-9: 5.26 %
  • 10-19: 2.63 %
  • 20-29: 10.53 %
  • 30-39: 15.79 %
  • 40-49: 28.95 %
  • 50-59: 15.79 %
  • 60+: 10.53 %

Top conditions involved for these people *:

  • Depression (6 people, 12.24%)
  • Schizoaffective Disorder (3 people, 6.12%)
  • Metabolic Syndrome (3 people, 6.12%)
  • Type 2 Diabetes (2 people, 4.08%)
  • Mania (2 people, 4.08%)

Top co-used drugs for these people *:

  • Levothyroxine Sodium (9 people, 18.37%)
  • Risperidone (8 people, 16.33%)
  • Lopressor (6 people, 12.24%)
  • Lithium Carbonate (6 people, 12.24%)
  • Effexor (6 people, 12.24%)

Top other side effects for these people *:

  • Weight Increased (8 people, 16.33%)
  • Fatigue (7 people, 14.29%)
  • Rhabdomyolysis (6 people, 12.24%)
  • Fainting (6 people, 12.24%)
  • Anaemia (6 people, 12.24%)

* Approximation only. Some reports may have incomplete information.

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Hypothyroidism and Valproic acid from FDA and eHealthMe reports

Valproic acid

Valproic acid has active ingredients of valproic acid. It is often used in epilepsy. (latest outcomes from Valproic acid 14,976 users)


Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development) has been reported by people with osteoporosis, high blood pressure, hypothyroidism, osteopenia, depression (latest reports from 85,737 Hypothyroidism patients).

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