Review: could Vicodin cause Sleeplessness?


Sleeplessness is found among people who take Vicodin, especially for people who are female, 60+ old , have been taking the drug for < 1 month, also take medication Zometa, and have Pain . We study 35,391 people who have side effects while taking Vicodin from FDA and social media. Among them, 1,692 have Sleeplessness. Find out below who they are, when they have Sleeplessness and more.

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Vicodin has active ingredients of acetaminophen; hydrocodone bitartrate. It is often used in pain. (latest outcomes from Vicodin 38,891 users)


Sleeplessness (a sleep disorder in which there is an inability to fall asleep or to stay asleep as long as desired) has been reported by people with breathing difficulty, suicidal ideation, thrombocytopenia, feeling abnormal, diarrhea (latest reports from 141,076 Sleeplessness patients).

On Aug, 23, 2016

35,391 people reported to have side effects when taking Vicodin.
Among them, 1,692 people (4.78%) have Sleeplessness

Number of reports submitted per year:

Could Vicodin cause Sleeplessness?

Time on Vicodin when people have Sleeplessness *:

  • < 1 month: 35.85 %
  • 1 - 6 months: 11.32 %
  • 6 - 12 months: 3.77 %
  • 1 - 2 years: 13.21 %
  • 2 - 5 years: 15.09 %
  • 5 - 10 years: 16.98 %
  • 10+ years: 3.77 %

Gender of people who have Sleeplessness when taking Vicodin *:

  • female: 65.02 %
  • male: 34.98 %

Age of people who have Sleeplessness when taking Vicodin *:

  • 0-1: 0.0 %
  • 2-9: 0.07 %
  • 10-19: 0.55 %
  • 20-29: 5.18 %
  • 30-39: 10.36 %
  • 40-49: 25.69 %
  • 50-59: 27.62 %
  • 60+: 30.52 %

Severity if Sleeplessness when taking Vicodin **:

  • least: 6.67 %
  • moderate: 40.0 %
  • severe: 40.0 %
  • most severe: 13.33 %

How people recovered from Sleeplessness **:

  • while on drug: 16.67 %
  • after off the drug: 16.67 %
  • not yet: 66.67 %

Top conditions involved for these people *:

  • Pain (362 people)
  • Depression (161 people)
  • Insomnia (114 people)
  • Anxiety (98 people)
  • Smoking Cessation Therapy (93 people)

Top co-used drugs for these people *:

  • Zometa (375 people)
  • Ambien (369 people)
  • Neurontin (355 people)
  • Xanax (353 people)
  • Oxycontin (330 people)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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