Review: could Vitamin B12 cause Flushing?


Flushing is found among people who take Vitamin B12, especially for people who are female, 60+ old , have been taking the drug for 2 - 5 years, also take medication Niaspan, and have Rheumatoid arthritis . We study 3,838 people who have side effects while taking Vitamin b12 from FDA and social media. Among them, 48 have Flushing. Find out below who they are, when they have Flushing and more.

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Vitamin B12

Vitamin b12 has active ingredients of cobalamin. It is often used in vitamin b12 deficiency. (latest outcomes from Vitamin b12 4,023 users)


Flushing (the warm, red condition of human skin) has been reported by people with breathing difficulty, rashes, feeling hot, ventricular septal defect, high blood cholesterol (latest reports from 42,295 Flushing patients).

On Jul, 20, 2016

3,838 people reported to have side effects when taking Vitamin B12.
Among them, 48 people (1.25%) have Flushing

Number of reports submitted per year:

Could Vitamin b12 cause Flushing?

Time on Vitamin B12 when people have Flushing *:

  • < 1 month: 0.0 %
  • 1 - 6 months: 33.33 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 16.67 %
  • 2 - 5 years: 33.33 %
  • 5 - 10 years: 16.67 %
  • 10+ years: 0.0 %

Gender of people who have Flushing when taking Vitamin B12 *:

  • female: 64.58 %
  • male: 35.42 %

Age of people who have Flushing when taking Vitamin B12 *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 2.86 %
  • 40-49: 31.43 %
  • 50-59: 28.57 %
  • 60+: 37.14 %

Severity if Flushing when taking Vitamin B12 **:

  • least: 0.0 %
  • moderate: 66.67 %
  • severe: 33.33 %
  • most severe: 0.0 %

How people recovered from Flushing **:

  • while on drug: 0.0 %
  • after off the drug: 0.0 %
  • not yet: 100 %

Top conditions involved for these people *:

  • Rheumatoid Arthritis (4 people)
  • Hypothyroidism (2 people)
  • Dysfunctional Uterine Bleeding (dub) (2 people)
  • Depression (2 people)
  • Acid Reflux (2 people)

Top co-used drugs for these people *:

  • Niaspan (24 people)
  • Vitamin E (12 people)
  • Folic Acid (11 people)
  • Vitamin B6 (9 people)
  • Aspirin (9 people)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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