Vitamin d and Hepatotoxicity - from FDA reports


Hepatotoxicity is found among people who take Vitamin D, especially for people who are female, 60+ old also take medication Calcium, and have Endocrine ophthalmopathy . We study 48,141 people who have side effects while taking Vitamin d from FDA. Among them, 13 have Hepatotoxicity. Find out below who they are, when they have Hepatotoxicity and more.

What to expect?

If you take Vitamin d and have Hepatotoxicity, find out what symptoms you could have in 1 year or longer.

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Vitamin D

Vitamin d has active ingredients of ergocalciferol. It is often used in rickets. (latest outcomes from Vitamin d 52,674 users)


Hepatotoxicity (chemical-driven liver damage) has been reported by people with hiv infection, pain, high blood pressure, preventive health care, rheumatoid arthritis (latest reports from 8,173 Hepatotoxicity patients).

On Feb, 14, 2017

48,141 people reported to have side effects when taking Vitamin D.
Among them, 13 people (0.03%) have Hepatotoxicity

Number of reports submitted per year:

Could Vitamin d cause Hepatotoxicity?

Gender of people who have Hepatotoxicity when taking Vitamin D *:

  • female: 60 %
  • male: 40 %

Age of people who have Hepatotoxicity when taking Vitamin D *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 30 %
  • 50-59: 10 %
  • 60+: 60 %

Top conditions involved for these people *:

  • Endocrine Ophthalmopathy (5 people, 38.46%)
  • Rheumatoid Arthritis (3 people, 23.08%)
  • Preventive Health Care (3 people, 23.08%)
  • Renal Cell Carcinoma (2 people, 15.38%)
  • Hypertensive Cardiomyopathy (2 people, 15.38%)

Top co-used drugs for these people *:

  • Calcium (8 people, 61.54%)
  • Humira (4 people, 30.77%)
  • Inflectra (3 people, 23.08%)
  • Enbrel (3 people, 23.08%)
  • Arava (3 people, 23.08%)

Top other side effects for these people *:

  • Fever (4 people, 30.77%)
  • Alanine Aminotransferase Increased (4 people, 30.77%)
  • Infusion Related Reaction (3 people, 23.08%)
  • General Physical Health Deterioration (3 people, 23.08%)
  • Eye Swelling (3 people, 23.08%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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