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Review: could Wellbutrin cause Hypersomnia (Drowsiness)?

Summary: Hypersomnia is found among people who take Wellbutrin, especially for people who are female, 50-59 old, have been taking the drug for < 1 month, also take medication Wellbutrin xl, and have Depression.

We study 49,335 people who have side effects while taking Wellbutrin from FDA and social media. Among them, 1,263 have Hypersomnia. Find out below who they are, when they have Hypersomnia and more.

You are not alone: join a support group for people who take Wellbutrin and have Hypersomnia >>>



Wellbutrin has active ingredients of bupropion hydrochloride. It is often used in depression. (latest outcomes from 55,078 Wellbutrin users)


Hypersomnia (excessive daytime sleepiness (eds)) has been reported by people with depression, pain, high blood pressure, multiple sclerosis, stress and anxiety. (latest reports from 69,920 Hypersomnia patients)

On Mar, 17, 2015: 49,335 people reported to have side effects when taking Wellbutrin. Among them, 1,263 people (2.56%) have Hypersomnia.

Trend of Hypersomnia in Wellbutrin reports

Time on Wellbutrin when people have Hypersomnia * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years

Age of people who have Hypersomnia when taking Wellbutrin * :


Severity of Hypersomnia when taking Wellbutrin ** :

leastmoderateseveremost severe

How people recovered from Hypersomnia ** :

while on the drugafter off the drugnot yet

Top conditions involved for these people * :

  1. Depression (465 people, 36.82%)
  2. Pain (147 people, 11.64%)
  3. Anxiety (77 people, 6.10%)
  4. Hypertension (77 people, 6.10%)
  5. Bipolar disorder (73 people, 5.78%)

Top co-used drugs for these people * :

  1. Wellbutrin xl (263 people, 20.82%)
  2. Wellbutrin sr (231 people, 18.29%)
  3. Paxil (184 people, 14.57%)
  4. Lexapro (163 people, 12.91%)
  5. Neurontin (158 people, 12.51%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Get connected: join our support group of wellbutrin and hypersomnia on

Do you have Hypersomnia while taking Wellbutrin?




You are not alone! Join a support group on :
- support group for people who take Wellbutrin and have Hypersomnia
- support group for people who take Wellbutrin
- support group for people who have Hypersomnia

Drugs in real world that are associated with:

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NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.


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