Review: could Wellbutrin cause Muscle Tightness?


Muscle tightness is found among people who take Wellbutrin, especially for people who are female, 50-59 old , have been taking the drug for < 1 month, also take medication Neurontin, and have Depression . We study 35,574 people who have side effects while taking Wellbutrin from FDA and social media. Among them, 104 have Muscle tightness. Find out below who they are, when they have Muscle tightness and more.

You are not alone

Join a support group for people who take Wellbutrin and have Muscle tightness >>>

Personalized health information

On eHealthMe you can find out what patients like me (same gender, age) reported their drugs and conditions on FDA and social media since 1977. Our tools are free and anonymous. 86 million people have used us. 300+ peer-reviewed medical journals have referenced our original studies. Start now >>>


Wellbutrin has active ingredients of bupropion hydrochloride. It is often used in depression. (latest outcomes from Wellbutrin 58,718 users)

Muscle Tightness

Muscle tightness has been reported by people with hypoaesthesia, breathing difficulty, fever, rashes, chest pain (latest reports from 5,992 Muscle tightness patients).

On Aug, 20, 2016

35,574 people reported to have side effects when taking Wellbutrin.
Among them, 104 people (0.29%) have Muscle Tightness

Number of reports submitted per year:

Could Wellbutrin cause Muscle tightness?

Time on Wellbutrin when people have Muscle Tightness *:

  • < 1 month: 57.14 %
  • 1 - 6 months: 28.57 %
  • 6 - 12 months: 14.29 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Muscle Tightness when taking Wellbutrin *:

  • female: 73.53 %
  • male: 26.47 %

Age of people who have Muscle Tightness when taking Wellbutrin *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 1.25 %
  • 20-29: 6.25 %
  • 30-39: 13.75 %
  • 40-49: 28.75 %
  • 50-59: 32.5 %
  • 60+: 17.5 %

Severity if Muscle Tightness when taking Wellbutrin **:

  • least: 0.0 %
  • moderate: 50 %
  • severe: 50 %
  • most severe: 0.0 %

Top conditions involved for these people *:

  • Depression (46 people)
  • Pain (14 people)
  • Gastrooesophageal Reflux Disease (12 people)
  • Multiple Sclerosis (11 people)
  • Hypercalcaemia (11 people)

Top co-used drugs for these people *:

  • Neurontin (20 people)
  • Benadryl (19 people)
  • Zoloft (17 people)
  • Gabapentin (16 people)
  • Compazine (16 people)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you have Muscle tightness when taking Wellbutrin?

Browse all side effects of Wellbutrin

a b c d e f g h i j k l m n o p q r s t u v w x y z

Drugs that are associated with Muscle tightness

Muscle tightness

Could your condition cause Muscle tightness

Muscle tightness

Can you answer these questions?

More questions for: Wellbutrin, Muscle tightness

You may be interested in these reviews

More reviews for: Wellbutrin, Muscle tightness

NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.