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Review: could Wellbutrin cause Muscle weakness?

Summary: Muscle weakness could be caused by Wellbutrin, especially for people who are female, 50-59 old, have been taking the drug for 1 - 6 months, also take Wellbutrin xl, and have Depression.

We study 48,927 people who have side effects while taking Wellbutrin from FDA and social media. Among them, 1,817 have Muscle weakness. Find out below who they are, when they have Muscle weakness and more.

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Wellbutrin

Wellbutrin (latest outcomes from 54,620 users) has active ingredients of bupropion hydrochloride. It is often used in depression.

Muscle weakness

Muscle weakness (a lack of muscle strength) (latest reports from 1,325,419 patients) has been reported by people with multiple sclerosis, high blood pressure, high blood cholesterol, osteoporosis, pain.

On Apr, 11, 2014: 48,777 people reported to have side effects when taking Wellbutrin. Among them, 1,822 people (3.74%) have Muscle Weakness. They amount to 0.14% of all the 1,323,204 people who have Muscle Weakness on eHealthMe.

Trend of Muscle weakness in Wellbutrin reports

Time on Wellbutrin when people have Muscle weakness * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years
Muscle weakness35.06%36.36%5.84%4.55%10.39%5.84%1.95%

Age of people who have Muscle weakness when taking Wellbutrin * :

0-12-910-1920-2930-3940-4950-5960+
Muscle weakness0.00%0.11%1.53%3.75%9.89%25.75%36.10%22.85%

Severity of Muscle weakness when taking Wellbutrin ** :

leastmoderateseveremost severe
Muscle weakness5.13%66.67%25.64%2.56%

How people recovered from Muscle weakness ** :

while on the drugafter off the drugnot yet
Muscle weakness0.00%0.00%100.00%

Top conditions involved for these people * :

  1. Depression (483 people, 26.51%)
  2. Pain (130 people, 7.14%)
  3. Hypertension (123 people, 6.75%)
  4. Multiple sclerosis (113 people, 6.20%)
  5. Gastrooesophageal reflux disease (92 people, 5.05%)

Top co-used drugs for these people * :

  1. Wellbutrin xl (344 people, 18.88%)
  2. Wellbutrin sr (267 people, 14.65%)
  3. Aspirin (263 people, 14.43%)
  4. Zoloft (255 people, 14.00%)
  5. Ambien (249 people, 13.67%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Related topic: Wellbutrin, Muscle weakness

You can also:

On eHealthMe, Wellbutrin (bupropion hydrochloride) is often used for depression. Find out below the conditions Wellbutrin is used for, how effective it is, and any alternative drugs that you can use to treat those same conditions.

What is Wellbutrin used for and how effective is it:

Other drugs that are used to treat the same conditions:

Could it be a symptom from a condition:

Drugs in real world that are associated with:

Could your condition cause it?

Comments from related studies:

  • From this study (7 months ago):

  • The asthenia does not interfere with my daily activities, however I have lost strength in weight lifting, I also can't move as quickly as I used to during exercise.
    In addition to anorgasmia, I have clitoral desensitization. Nothing excites me anymore. This has really interfered with my sexual relationship with my husband.

    Reply

  • From this study (7 months ago):

  • The asthenia does not interfere with daily activities. However, I lift weights and participate in aerobic classes and I have noticed a dramatic decrease in my strength and aerobic capacity.

    Reply

  • From this study (13 months ago):

  • Kevin Peters Ph.d on Mar, 4, 2013:

    Sammy, I'm a white 45 male; just wanted to agree on that Klonopin remark. When I was 21 I had my second kidney transplant which was a BAD issue all together, at any rate the hospital did not include my medications taken at home after my surgery. I went thru the worst hallucinations and jerking and seizures you could ever possibly imagine. This went on for almost 3 1/2 weeks before we decided to have me taken OUT of the hospital and relocated before they ended up taking my life. Then the whole staff of paychology including the chief of psychiatry cane in my room to see what they could do, Finallu. During one of my few moments of clarity the C.O.F after blaming me if talking "drugs" prior to my transplant listened to my word of telling him the meds I was on before being admitted. After asking when was the last time I had received my Klonopin and me not knowing, he then reviewed the charts, and didn't see me receiving this med once. He stormed out of the room of about 9 docs and came back in with two Klonopin; for the first time in almost 4 weeks and after three surgeries the first 72 hours I was hospitalized, I was sleeping like a baby, for about 49 hours with NO MORE hallucinations, or seizures or jerking! I finally got out of there without a kidney since that kidney was supposed to go to another man named the same as I in a different city! I do take Xanax and probably always will. The half life on Klonopin is much different hence one if its dangers, Nevwr Ever stop this drug cold! I've been on dialysis 25 1/2 years now and suffered from intense skin cancers, but have fought and done all I can do to live a normal as possible life, working full time except when I'm in yet another surgery, over 32 general anesthetic procedures since 1987. I was the youngest boy-man to ever be on the USA soccer team ready to play in the Korea 1988 Olympics. What a change in life.....
    All the Best,
    K. Peters

    Reply

    chris on Jun, 4, 2011:

    i have been taking clonzepam and trazedone and my speech is a very hoarse voice, I am wondering if if my speech problem is from these drugs's side effects.

    Reply

    TwoDimes on Apr, 15, 2012:

    Upon occasion, I, too, have become hoarse and from the use of Klonopin. I was VERY hoarse when I tried to cold turkey off of 4mgs of Klonopin. I am now down to 1.5mgs per day and, still, (as I said, upon occasion, I become hoarse. I am sure that the use of Klonopin is the causative factor. - TwoDimes -

    Reply

    SammySushi on Jul, 10, 2012:

    Omigosh, never cold turkey clonopin, esp that high of a dose. My dad had a major seizure and hallucinations doing so.

    Reply

    Christophe on Nov, 13, 2012:

    Hello,
    I suffer from Hypothyroidism, High Cholesterol & Cancer survivor because of Zyprexa use and previously being prescribed Carbamezapine causing Thyroid damage. My best advice to you if you don't want Hypothyroidism is have regular blood tests, Thyroid damage can be undetected for up to 5 years with no symptoms found on regular blood tests prematurally. Make sure you buy iodised salt to use on food when eating this will help reduce your risk of getting Hypothyroidism. two signs of Hypothyriodism which the Carbamezapine & Zyprexa medication boxes labels wont tell you is if your face becomes puffed up, red or sun sensitive while taking these medications this is a sign of Hypothyroidism. It wont be found on your blood test but later on it could appear out of the blue. The other sign to look for is baldness or hair loss on your head, this is another symptom. I hope these comments will help you. You have to weight up the benefits and negatives taking medications if you decide to take these medicines or not. It depends on how you cope with the drug side effects.
    from Christophe

    Reply

    AUDREY on Dec, 16, 2012:

    STARTED TAKING DILTIAZEM 60 MG AND I AM VERY CONSTIPATED. 70 YEARS OLD, HEART SURGERY A FAST HEART RATE....

    Reply

    Sonya on Feb, 24, 2013:

    You definately need to take a stool softener...straining during defication can cause major problems in people with cardiac problems.

    Reply

Post a new comment    OR    Read more comments

Can you answer these questions (what is this?):

  • Exercise intolerance
    I've been running for 2 years and recently it has become harder to run and I've lost 45 seconds off my pace. It's harder becuase my hips/.thighs hurt and not because of reduced lung capacity. It isn't temperature related. I've been taking 40 mg Prozac, 450 mg Wellbutrin, and .5 mg Xanax XR for 4 y ...

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    I had 9 injections of lupron after a partial hysterectomy. Ever since then my body has never been the same. I continue, 3 years later suffering from weakness. I had to quit my job as a registered nurse and after 2 and 1/2 years I was forced to file for disability.

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More reviews for: Wellbutrin, Muscle weakness

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