Review: could Wellbutrin cause Neuroleptic Malignant Syndrome?


Neuroleptic malignant syndrome is found among people who take Wellbutrin, especially for people who are female, 60+ old , have been taking the drug for < 1 month, also take medication Seroquel, and have Depression . We study 43,580 people who have side effects while taking Wellbutrin from FDA and social media. Among them, 71 have Neuroleptic malignant syndrome. Find out below who they are, when they have Neuroleptic malignant syndrome and more.

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Wellbutrin has active ingredients of bupropion hydrochloride. It is often used in depression. (latest outcomes from Wellbutrin 70,587 users)

Neuroleptic Malignant Syndrome

Neuroleptic malignant syndrome (a life-threatening neurological disorder most often caused by an adverse reaction to neuroleptic or antipsychotic agents) has been reported by people with schizophrenia, depression, bipolar disorder, psychotic disorder, parkinson's disease (latest reports from 9,414 Neuroleptic malignant syndrome patients).

On Oct, 20, 2016

43,580 people reported to have side effects when taking Wellbutrin.
Among them, 71 people (0.16%) have Neuroleptic Malignant Syndrome

Number of reports submitted per year:

Could Wellbutrin cause Neuroleptic malignant syndrome?

Time on Wellbutrin when people have Neuroleptic Malignant Syndrome *:

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Neuroleptic Malignant Syndrome when taking Wellbutrin *:

  • female: 61.19 %
  • male: 38.81 %

Age of people who have Neuroleptic Malignant Syndrome when taking Wellbutrin *:

  • 0-1: 1.82 %
  • 2-9: 0.0 %
  • 10-19: 3.64 %
  • 20-29: 9.09 %
  • 30-39: 20.0 %
  • 40-49: 20.0 %
  • 50-59: 20.0 %
  • 60+: 25.45 %

Top conditions involved for these people *:

  • Depression (18 people, 25.35%)
  • Bipolar Disorder (13 people, 18.31%)
  • Schizophrenia (9 people, 12.68%)
  • Sleep Disorder (7 people, 9.86%)
  • Insomnia (6 people, 8.45%)

Top co-used drugs for these people *:

  • Seroquel (34 people, 47.89%)
  • Zyprexa (22 people, 30.99%)
  • Risperdal (20 people, 28.17%)
  • Depakote (14 people, 19.72%)
  • Lexapro (13 people, 18.31%)

Top other side effects for these people *:

  • Pyrexia (13 people, 18.31%)
  • Diabetes Mellitus (13 people, 18.31%)
  • Blood Creatine Phosphokinase Increased (12 people, 16.90%)
  • Type 2 Diabetes Mellitus (11 people, 15.49%)
  • Muscle Rigidity (8 people, 11.27%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

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