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Review: could Wellbutrin cause Neuroleptic malignant syndrome?

Summary: Neuroleptic malignant syndrome could be caused by Wellbutrin, especially for people who are female, 60+ old, have been taking the drug for < 1 month, also take Seroquel, and have Depression.

We study 48,927 people who have side effects while taking Wellbutrin from FDA and social media. Among them, 84 have Neuroleptic malignant syndrome. Find out below who they are, when they have Neuroleptic malignant syndrome and more.

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Wellbutrin

Wellbutrin (latest outcomes from 54,620 users) has active ingredients of bupropion hydrochloride. It is often used in depression, stress and anxiety. Commonly reported side effects of Wellbutrin include nausea, nausea aggravated, depression, stress and anxiety, depression aggravated.

Neuroleptic malignant syndrome

Neuroleptic malignant syndrome (a life-threatening neurological disorder most often caused by an adverse reaction to neuroleptic or antipsychotic agents) (latest reports from 32,678 patients) has been reported by people with schizophrenia, depression, bipolar disorder, psychotic disorder, parkinson's disease.

On Apr, 12, 2014: 48,927 people reported to have side effects when taking Wellbutrin. Among them, 84 people (0.17%) have Neuroleptic Malignant Syndrome. They amount to 0.26% of all the 32,661 people who have Neuroleptic Malignant Syndrome on eHealthMe.

Trend of Neuroleptic malignant syndrome in Wellbutrin reports

Time on Wellbutrin when people have Neuroleptic malignant syndrome * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years
Neuroleptic malignant syndrome100.00%0.00%0.00%0.00%0.00%0.00%0.00%

Age of people who have Neuroleptic malignant syndrome when taking Wellbutrin * :

0-12-910-1920-2930-3940-4950-5960+
Neuroleptic malignant syndrome4.55%0.00%4.55%7.58%19.70%21.21%21.21%21.21%

Severity of Neuroleptic malignant syndrome when taking Wellbutrin ** :

n/a

How people recovered from Neuroleptic malignant syndrome ** :

n/a

Top conditions involved for these people * :

  1. Depression (20 people, 23.81%)
  2. Bipolar disorder (14 people, 16.67%)
  3. Schizophrenia (13 people, 15.48%)
  4. Sleep disorder (8 people, 9.52%)
  5. Agitation (5 people, 5.95%)

Top co-used drugs for these people * :

  1. Seroquel (37 people, 44.05%)
  2. Risperdal (25 people, 29.76%)
  3. Zyprexa (24 people, 28.57%)
  4. Depakote (15 people, 17.86%)
  5. Lexapro (15 people, 17.86%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Related topic: Wellbutrin, Neuroleptic malignant syndrome

You can also:

On eHealthMe, Wellbutrin (bupropion hydrochloride) is often used for depression. Find out below the conditions Wellbutrin is used for, how effective it is, and any alternative drugs that you can use to treat those same conditions.

What is Wellbutrin used for and how effective is it:

Other drugs that are used to treat the same conditions:

Could it be a symptom from a condition:

Drugs in real world that are associated with:

Could your condition cause it?

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NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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