Wellbutrin and Serotonin syndrome - from FDA reports


Summary

Serotonin syndrome is found among people who take Wellbutrin, especially for people who are female, 50-59 old , have been taking the drug for < 1 month, also take medication Cymbalta, and have Depression . We study 60,730 people who have side effects while taking Wellbutrin from FDA. Among them, 194 have Serotonin syndrome. Find out below who they are, when they have Serotonin syndrome and more.

What to expect?

If you take Wellbutrin and have Serotonin syndrome, find out what symptoms you could have in 1 year or longer.

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Wellbutrin

Wellbutrin has active ingredients of bupropion hydrochloride. It is often used in depression. (latest outcomes from Wellbutrin 70,871 users)

Serotonin Syndrome

Serotonin syndrome (occurs when two drugs that affect the body's level of serotonin are taken together at the same time) has been reported by people with depression, pain, stress and anxiety, major depression, insomnia (latest reports from 9,744 Serotonin syndrome patients).

On Jan, 29, 2017

60,730 people reported to have side effects when taking Wellbutrin.
Among them, 194 people (0.32%) have Serotonin Syndrome


Number of reports submitted per year:

Could Wellbutrin cause Serotonin syndrome?

Time on Wellbutrin when people have Serotonin Syndrome *:

  • < 1 month: 40 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 20 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 40 %

Gender of people who have Serotonin Syndrome when taking Wellbutrin *:

  • female: 67.98 %
  • male: 32.02 %

Age of people who have Serotonin Syndrome when taking Wellbutrin *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 3.03 %
  • 20-29: 6.82 %
  • 30-39: 9.85 %
  • 40-49: 15.15 %
  • 50-59: 34.85 %
  • 60+: 30.3 %

Top conditions involved for these people *:

  • Depression (69 people, 35.57%)
  • Stress And Anxiety (26 people, 13.40%)
  • Pain (18 people, 9.28%)
  • Quit Smoking (12 people, 6.19%)
  • Analgesic Therapy (11 people, 5.67%)

Top co-used drugs for these people *:

  • Cymbalta (40 people, 20.62%)
  • Prozac (31 people, 15.98%)
  • Paxil (27 people, 13.92%)
  • Zoloft (22 people, 11.34%)
  • Clonazepam (22 people, 11.34%)

Top other side effects for these people *:

  • Agitation (28 people, 14.43%)
  • Feeling Abnormal (27 people, 13.92%)
  • Tremor (21 people, 10.82%)
  • Nausea (18 people, 9.28%)
  • High Blood Pressure (15 people, 7.73%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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