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Review: could Wellbutrin cause Stroke?

Summary: Stroke could be caused by Wellbutrin, especially for people who are female, 50-59 old, have been taking the drug for 2 - 5 years, also take Vioxx, and have Depression.

We study 48,927 people who have side effects while taking Wellbutrin from FDA and social media. Among them, 560 have Stroke. Find out below who they are, when they have Stroke and more.

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Wellbutrin

Wellbutrin (latest outcomes from 54,620 users) has active ingredients of bupropion hydrochloride. It is often used in depression.

Stroke

Stroke (sudden death of a portion of the brain cells due to a lack of oxygen) (latest reports from 444,411 patients) has been reported by people with diabetes, arthritis, high blood pressure, pain, pain relief by acupuncture.

On Apr, 10, 2014: 48,777 people reported to have side effects when taking Wellbutrin. Among them, 560 people (1.15%) have Stroke. They amount to 0.13% of all the 440,145 people who have Stroke on eHealthMe.

Trend of Stroke in Wellbutrin reports

Time on Wellbutrin when people have Stroke * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years
Stroke20.00%17.14%17.14%5.71%28.57%11.43%0.00%

Age of people who have Stroke when taking Wellbutrin * :

0-12-910-1920-2930-3940-4950-5960+
Stroke0.00%0.00%0.78%2.52%10.08%23.45%34.88%28.29%

Severity of Stroke when taking Wellbutrin ** :

leastmoderateseveremost severe
Stroke100.00%0.00%0.00%0.00%

How people recovered from Stroke ** :

n/a

Top conditions involved for these people * :

  1. Depression (146 people, 26.07%)
  2. Pain (72 people, 12.86%)
  3. Hypertension (52 people, 9.29%)
  4. Anxiety (47 people, 8.39%)
  5. Arthritis (39 people, 6.96%)

Top co-used drugs for these people * :

  1. Vioxx (219 people, 39.11%)
  2. Plavix (122 people, 21.79%)
  3. Lipitor (107 people, 19.11%)
  4. Aspirin (95 people, 16.96%)
  5. Lasix (95 people, 16.96%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

Comments for this study:

med7 (2 years ago):

39/f... ridiculously healthy medically with exception of depression,anxiety, adhd. Went off all meds while pregnant. More depression and anxiety following two miscarriages last year, first at 17 weeks, second on due date of first baby miscarried. Now unable to conceive. Thought that sucked, until I had a full out stroke while at work last Monday (im in medicine). Come to realize, this is actually the second time. One same time last year. Full evaluaion and all okay; no major damage. But the only thing the docs can attribute the strokes to is the wellbutrin. Be careful. I used to be on 450mg and read that it was too dangerous. Now on 300mg at time of event. Still too much, I guess. Scary stuff,especially when your very livelihood (never mind life) depends on it.
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Related topic: Wellbutrin, Stroke

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On eHealthMe, Wellbutrin (bupropion hydrochloride) is often used for depression. Find out below the conditions Wellbutrin is used for, how effective it is, and any alternative drugs that you can use to treat those same conditions.

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NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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