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Review: could Xanax cause Anger?

Summary: Anger could be caused by Xanax, especially for people who are female, 40-49 old, have been taking the drug for 2 - 5 years, also take Chantix, and have Depression.

We study 54,772 people who have side effects while taking Xanax from FDA and social media. Among them, 576 have Anger. Find out below who they are, when they have Anger and more.

How are my drugs for patients like me? On eHealthMe, you can research 300 million drug outcomes from FDA and social media. All studies are personalized to gender and age. Start now, it's anonymous, simple & free >>>

On Apr, 11, 2014: 54,772 people reported to have side effects when taking Xanax. Among them, 576 people (1.05%) have Anger. They amount to 0.59% of all the 96,923 people who have Anger on eHealthMe.

Trend of Anger in Xanax reports

Time on Xanax when people have Anger * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years

Gender of people who have Anger when taking Xanax * :


Age of people who have Anger when taking Xanax * :


Severity of Anger when taking Xanax ** :

leastmoderateseveremost severe

How people recovered from Anger ** :

while on the drugafter off the drugnot yet

Top conditions involved for these people * :

  1. Depression (185 people, 32.12%)
  2. Anxiety (174 people, 30.21%)
  3. Smoking cessation therapy (115 people, 19.97%)
  4. Sleep disorder (67 people, 11.63%)
  5. Pain (61 people, 10.59%)

Top co-used drugs for these people * :

  1. Chantix (128 people, 22.22%)
  2. Ambien (120 people, 20.83%)
  3. Zoloft (106 people, 18.40%)
  4. Lexapro (104 people, 18.06%)
  5. Seroquel (100 people, 17.36%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Related topic: Xanax, Anger

You can also:

On eHealthMe, Xanax (alprazolam) is often used for stress and anxiety. Find out below the conditions Xanax is used for, how effective it is, and any alternative drugs that you can use to treat those same conditions.

What is Xanax used for and how effective is it:

Other drugs that are used to treat the same conditions:

Could it be a symptom from a condition:

Drugs in real world that are associated with:

Could your condition cause it?

Comments from related studies:

  • From this study (7 months ago):

  • My tremors are horrible and anxiety, anger , loss of interest in many things, work related depression and defeat....worthlessness.


  • From this study (13 months ago):

  • My Pdoc recently put me on 1/4th of 50mg of Pristiq in addition to the other two Rxs. I am not prone to headaches and the very day I tried the dosage, I got a severe migraine that lasted two says. I stopped the Rx immediately and reported side effect to my doctor.

    We then tried 1/8 of the Pristiq along with my other Rxs. The severe headaches did not return, thankfully. However, I have started to experience feelings of severe anger (which is totally unlike me).

    Fortunately, the feelings of Depression and SI have almost subsided but the anger I am feeling is very unsettling. I am so used to turning my feelings inward and punishing myself by feeling supremely depressed...

    ...I have been on 1/8 of the pill for about a week now and I am going to stop taking it. I have an appt with doc in a week.

    I would rather feel incredibly sad for a few days than to go completely ballistic. It is very scary.

    I don't think this is the right Rx for me.


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

Related study

- Xanax side effects


Related symptom

- Anger



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