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Review: could Xarelto cause Headache?

We study 4,518 people who have side effects while taking Xarelto from FDA and social media. Among them, 98 have Headache. Find out below who they are, when they have Headache and more.

Stay connected: join a mobile support group for people who take Xarelto and have Headache >>>

Xarelto

Xarelto (latest outcomes from 4,643 users) has active ingredients of rivaroxaban. It is often used in atrial fibrillation/flutter.

Headache

Headache (pain in head) (latest reports from 1,204,327 patients) has been reported by people with multiple sclerosis, high blood pressure, depression, rheumatoid arthritis, osteoporosis.

On Jul, 13, 2014: 4,513 people reported to have side effects when taking Xarelto. Among them, 98 people (2.17%) have Headache. They amount to 0.01% of all the 1,194,725 people who have Headache on eHealthMe.

Trend of Headache in Xarelto reports

Time on Xarelto when people have Headache * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years
Headache66.67%31.67%0.00%0.00%0.00%0.00%1.67%

Gender of people who have Headache when taking Xarelto * :

FemaleMale
Headache62.12%37.88%

Age of people who have Headache when taking Xarelto * :

0-12-910-1920-2930-3940-4950-5960+
Headache0.00%0.00%0.00%0.81%1.61%8.87%6.45%82.26%

Severity of Headache when taking Xarelto ** :

leastmoderateseveremost severe
Headache9.09%45.45%36.36%9.09%

How people recovered from Headache ** :

while on the drugafter off the drugnot yet
Headache0.00%10.00%90.00%

Top conditions involved for these people * :

  1. Atrial fibrillation (62 people, 63.27%)
  2. Blood cholesterol (18 people, 18.37%)
  3. Blood pressure (18 people, 18.37%)
  4. Anxiety (13 people, 13.27%)
  5. Cardiac disorder (13 people, 13.27%)

Top co-used drugs for these people * :

  1. Xanax (21 people, 21.43%)
  2. Aspirin (17 people, 17.35%)
  3. Metoprolol tartrate (17 people, 17.35%)
  4. Lasix (15 people, 15.31%)
  5. Allopurinol (13 people, 13.27%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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Comments from related studies:

  • From this study (1 month ago):

  • I have paroxysmal atrial fibrillation, history of clots in lung & legs, blockage in legs (had fempop 2 yrs ago), asthma & w/o warning while sitting down all of a sudden I got a severe headache, then about 30 min late got severe nausea (but didn't vomit)chest pain & mild dizziness followed so I took my BP and it was 170/93 P 64 then 164/100 P 70. This has happen several times in the same amount of weeks

    Reply

  • From this study (10 months ago):

  • due to the above drugs mentioned along with associated symptoms . it is noted the at I have a pineal brain cyst 6mm in size. not advancing. the guess that I was born with it. however, after talking to the skull base organization action out in Los Angeles.

    a major car accident in June 14th was reported as 'unknown cause possible seizure. I'm ask in more in depth testing

    Reply

  • From this study (10 months ago):

  • G Conner on Jul, 31, 2012:

    female, age 65, Texas
    I am on both Xraelto and Flecainade. I have had a headache all month since I started Flecainade. Wonder if those will go away after a while, some are severe, or the drug needs changing. I had atrial fibrillation, no valve problems and shocked on 7/3.

    Reply

    Dawn on Dec, 30, 2012:

    I'm 40 years old and I've been on this drug for two months now and the headaches havent gone away. I'm on this because I have an MTHFR mutation that causes blood clots in my legs. I'm keeping my fingers crossed that this, along with the welling and tired feeling go away.

    Reply

    Mark on Mar, 27, 2013:

    Hi Dawn,

    I too am on Xarelto (20MG daily)for DVT/PE. Have some headaches as well. Usally after I take the dose at dinner meal. I did find some information about FDA trials of this drug. The drug company had subjects on 10 mg twicw daily during some of the reasearch. FDA did challenge as to why they went to a single dose of 20mg. I have thought perhaps changing to 10 mg twice daily.

    Reply

    Mark on Mar, 27, 2013:

    Male, 58 yrs, currently on Xarelto for DVT /PE. Xarelto mfg. had trials done using 10 mg x 2 daily dose after the initial 15 mg x 2 daily.
    FDA did challenge as to why dose was changed to a single dose after drug was made public. I get a headache after my 20 mg dose at dinnertime.
    I wonder if the current dose of 20 mg daily might be too much for some people to tolerate.
    I am contacting my Doc. to see if 10 mg X 2 daily would be an option.

    Reply

    christy rowan on May, 26, 2013:

    I am on my 2nd month of xarelto. I was on couladon prior. I have anticardiolipin antibody syndrome... I am suffering from terriblr headaches, and sometimes lightheadedness. Trying to determine if it is from xarelto, or somedmething else. Any thoughts are appreciated.

    Reply

    msemm22 on Sep, 23, 2013:

    I am having the exact same issues. I have anticardiolipid antibody and was previously on Coumadin, now I have been on Xarelto for approx. 3 months. It's great not having to monitor but the headaches and lightheadedness don't out way the positives. My PCP is convinced it is the Xarelto but my Hematologist thinks differently. You aren't alone. Any feedback from anyone would be much appreciated!!

    Reply

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More reviews for: Xarelto, Headache

On eHealthMe, Xarelto (rivaroxaban) is often used for atrial fibrillation/flutter. Find out below the conditions Xarelto is used for, how effective it is, and any alternative drugs that you can use to treat those same conditions.

What is Xarelto used for and how effective is it:

Other drugs that are used to treat the same conditions:

Could it be a symptom from a condition:

Drugs in real world that are associated with:

Could your condition cause it?

NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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