Review: could Xeloda cause Large Intestine Perforation?


Summary

Large intestine perforation is found among people who take Xeloda, especially for people who are male, 60+ old , have been taking the drug for < 1 month, also take medication Avastin, and have Rectal cancer . We study 23,290 people who have side effects while taking Xeloda from FDA and social media. Among them, 60 have Large intestine perforation. Find out below who they are, when they have Large intestine perforation and more.

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Xeloda

Xeloda has active ingredients of capecitabine. It is often used in breast cancer. (latest outcomes from Xeloda 27,571 users)

Large Intestine Perforation

Large intestine perforation (hole in large intestine) has been reported by people with itching, xerosis (latest reports from 3,976 Large intestine perforation patients).

On Aug, 25, 2016

23,290 people reported to have side effects when taking Xeloda.
Among them, 60 people (0.26%) have Large Intestine Perforation


Number of reports submitted per year:

Could Xeloda cause Large intestine perforation?

Time on Xeloda when people have Large Intestine Perforation *:

  • < 1 month: 58.97 %
  • 1 - 6 months: 35.9 %
  • 6 - 12 months: 5.13 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Large Intestine Perforation when taking Xeloda *:

  • female: 32.14 %
  • male: 67.86 %

Age of people who have Large Intestine Perforation when taking Xeloda *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 1.92 %
  • 40-49: 17.31 %
  • 50-59: 38.46 %
  • 60+: 42.31 %

Top conditions involved for these people *:

  • Rectal Cancer (17 people, 28.33%)
  • Colon Cancer Metastatic (6 people, 10.00%)
  • Colon Cancer (6 people, 10.00%)
  • Rectal Cancer Metastatic (5 people, 8.33%)
  • Neoplasm Malignant (5 people, 8.33%)

Top co-used drugs for these people *:

  • Avastin (28 people, 46.67%)
  • Oxaliplatin (16 people, 26.67%)
  • Elplat (11 people, 18.33%)
  • Loxonin (6 people, 10.00%)
  • Zocor (5 people, 8.33%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

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