Xeloda and Large intestine perforation - from FDA reports


Summary

Large intestine perforation is found among people who take Xeloda, especially for people who are male, 60+ old , have been taking the drug for < 1 month, also take medication Avastin, and have Rectal cancer. This review analyzes which people have Large intestine perforation with Xeloda. It is created by eHealthMe based on reports of 27,913 people who have side effects when taking Xeloda from FDA, and is updated regularly.

What to expect?

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On Mar, 28, 2017

27,913 people reported to have side effects when taking Xeloda.
Among them, 72 people (0.26%) have Large Intestine Perforation


Number of reports submitted per year:

Could Xeloda cause Large intestine perforation?

Time on Xeloda when people have Large Intestine Perforation *:

  • < 1 month: 64.44 %
  • 1 - 6 months: 31.11 %
  • 6 - 12 months: 4.44 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Large Intestine Perforation when taking Xeloda *:

  • female: 33.82 %
  • male: 66.18 %

Age of people who have Large Intestine Perforation when taking Xeloda *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 1.56 %
  • 40-49: 14.06 %
  • 50-59: 34.38 %
  • 60+: 50.0 %

Top conditions involved for these people *:

  • Rectal Cancer (20 people, 27.78%)
  • Colon Cancer (12 people, 16.67%)
  • Colon Cancer Metastatic (7 people, 9.72%)
  • Rectal Cancer Metastatic (6 people, 8.33%)
  • Breast Cancer (5 people, 6.94%)

Top co-used drugs for these people *:

  • Avastin (35 people, 48.61%)
  • Oxaliplatin (16 people, 22.22%)
  • Zocor (5 people, 6.94%)
  • Simvastatin (4 people, 5.56%)
  • Compazine (4 people, 5.56%)

Top other side effects for these people *:

  • Peritonitis (12 people, 16.67%)
  • Diarrhea (9 people, 12.50%)
  • Intestinal Ischaemia (7 people, 9.72%)
  • Rectal Perforation (6 people, 8.33%)
  • Sepsis (5 people, 6.94%)

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you have Large intestine perforation when taking Xeloda?

Xeloda

Xeloda has active ingredients of capecitabine. It is often used in breast cancer metastatic. (latest outcomes from Xeloda 28,767 users)

Large Intestine Perforation

Large intestine perforation (hole in large intestine) has been reported by people with rheumatoid arthritis, crohn's disease, high blood pressure, multiple sclerosis, pain (latest reports from 4,316 Large intestine perforation patients).

Browse all side effects of Xeloda

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Drugs that are associated with Large intestine perforation

Large intestine perforation

Could your condition cause Large intestine perforation

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What would happen?

Forecast new side effects and undetected conditions when you take Xeloda and have Large intestine perforation.

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