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Review: could Xeloda cause Large intestine perforation?

Summary: Large intestine perforation is found among people who take Xeloda, especially for people who are male, 60+ old, have been taking the drug for < 1 month, also take medication Avastin, and have Rectal cancer.

We study 18,060 people who have side effects while taking Xeloda from FDA and social media. Among them, 54 have Large intestine perforation. Find out below who they are, when they have Large intestine perforation and more.

You are not alone: join a mobile support group for people who take Xeloda and have Large intestine perforation >>>

 

 

 

 

Xeloda

Xeloda has active ingredients of capecitabine. It is often used in colon cancer. (latest outcomes from 18,174 Xeloda users)

Large intestine perforation

Large intestine perforation (hole in large intestine) has been reported by people with rheumatoid arthritis, crohn's disease, high blood pressure, multiple sclerosis, hyperphosphataemia. (latest reports from 2,795 Large intestine perforation patients)

On Jan, 25, 2015: 18,060 people reported to have side effects when taking Xeloda. Among them, 54 people (0.30%) have Large Intestine Perforation.

Trend of Large intestine perforation in Xeloda reports

Time on Xeloda when people have Large intestine perforation * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years
Large intestine perforation60.00%37.14%2.86%0.00%0.00%0.00%0.00%

Age of people who have Large intestine perforation when taking Xeloda * :

0-12-910-1920-2930-3940-4950-5960+
Large intestine perforation0.00%0.00%0.00%0.00%0.00%23.08%38.46%38.46%

Severity of Large intestine perforation when taking Xeloda ** :

n/a

How people recovered from Large intestine perforation ** :

n/a

Top conditions involved for these people * :

  1. Rectal cancer (16 people, 29.63%)
  2. Neoplasm malignant (5 people, 9.26%)
  3. Rectal cancer metastatic (4 people, 7.41%)
  4. Nausea (4 people, 7.41%)
  5. Colon cancer metastatic (4 people, 7.41%)

Top co-used drugs for these people * :

  1. Avastin (26 people, 48.15%)
  2. Oxaliplatin (16 people, 29.63%)
  3. Elplat (8 people, 14.81%)
  4. Loxonin (6 people, 11.11%)
  5. Zocor (6 people, 11.11%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you have Large Intestine Perforation while taking Xeloda?

You are not alone! Join a mobile support group:
- support group for people who take Xeloda and have Large Intestine Perforation
- support group for people who take Xeloda
- support group for people who have Large Intestine Perforation

Drugs in real world that are associated with:

Could your condition cause:

Can you answer these questions (Ask a question):

  • Trouble breathing on xeloda
    Been on 3000 mil of xeloda for 5 treatments. Last one at start of 7 days off breathing just got more difficult to walk from room to room
  • My father take xeloda and have muscle pain which drug he can take ?
    My father have secum adenocarcinoma and remove them with surgery now he take xeloda 500 2pill morning and 2 pill night but he had muscle pain.
  • How long before hair loss after starting on xeloda (1 answer)
    first time using this drug,was concerned about hair loss. Approximate time you should expect possible hair loss
  • Finding more tumore after 4 cycles of xeloda
    On 20/2/2013 my wife is a 42 years old with the diagnosis of locally advanced left breast cancer (T4b) & clinically positive left supraclavicular & axillary lymph nodes (N3) " invasive ductal carcinoma " . Immunophenotyping was +ve for ER & PR (4/8) , -ve for HER2 (1) with ki-67 =4% .

    She started neoadjuvant treatment FEC75 , every 21 days , 2nd & 3rd cycles with a reduction of 20% .

    after that 4 cycles of Navelbine with Xeloda every 2 weeks and one weeks off

    after 2 cycles of Xeloda there was a great response on tumor size , but after the other 2 cylce of Xeloda a new 3 Tumor was found on the same breast .

    is that normal and what is the next step
  • Is there a remedy for uti caused by side effect to xeloda
    My GP thinks that my symptoms of UTI may be as a result of taking Xeloda. Is there a remedy to cure it other than antibiotics

More questions for: Xeloda, Large intestine perforation

More reviews for: Xeloda, Large intestine perforation

Comments from related studies:

  • From this study (1 week ago):

  • Xeloda for cancer caused severe pukes when dose upped to 1500mg bid from 1000mg

    Reply

  • From this study (2 months ago):

  • My nose drips constantly - a clear drip that is noticeable by others. I go through boxes of tissues.

    Reply

  • From this study (5 months ago):

  • Have been on Xeloda 5days. 2000mg bid and past few days intermittent chest and arm pain. I had check up at hospital, including a stress test which was all normal. Pain fells like muscle tightness and comes on after exertion.

    Reply

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