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Review: could Xeloda cause Large intestine perforation?

We study 18,058 people who have side effects while taking Xeloda from FDA and social media. Among them, 54 have Large intestine perforation. Find out below who they are, when they have Large intestine perforation and more.

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Xeloda

Xeloda (latest outcomes from 18,171 users) has active ingredients of capecitabine. It is often used in colon cancer.

Large intestine perforation

Large intestine perforation (hole in large intestine) (latest reports from 14,099 patients) has been reported by people with rheumatoid arthritis, crohn's disease, high blood pressure, multiple sclerosis, hyperphosphataemia.

On Sep, 2, 2014: 18,058 people reported to have side effects when taking Xeloda. Among them, 54 people (0.30%) have Large Intestine Perforation. They amount to 0.38% of all the 14,092 people who have Large Intestine Perforation on eHealthMe.

Trend of Large intestine perforation in Xeloda reports

Time on Xeloda when people have Large intestine perforation * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years
Large intestine perforation60.00%37.14%2.86%0.00%0.00%0.00%0.00%

Age of people who have Large intestine perforation when taking Xeloda * :

0-12-910-1920-2930-3940-4950-5960+
Large intestine perforation0.00%0.00%0.00%0.00%0.00%23.08%38.46%38.46%

Severity of Large intestine perforation when taking Xeloda ** :

n/a

How people recovered from Large intestine perforation ** :

n/a

Top conditions involved for these people * :

  1. Rectal cancer (16 people, 29.63%)
  2. Neoplasm malignant (5 people, 9.26%)
  3. Rectal cancer metastatic (4 people, 7.41%)
  4. Nausea (4 people, 7.41%)
  5. Colon cancer metastatic (4 people, 7.41%)

Top co-used drugs for these people * :

  1. Avastin (26 people, 48.15%)
  2. Oxaliplatin (16 people, 29.63%)
  3. Elplat (8 people, 14.81%)
  4. Loxonin (6 people, 11.11%)
  5. Zocor (6 people, 11.11%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you have Large Intestine Perforation while taking Xeloda?

Get connected! Join a mobile support group:
- group for people who take Xeloda and have Large Intestine Perforation
- group for people who take Xeloda
- group for people who have Large Intestine Perforation

Comments from related studies:

  • From this study (2 days ago):

  • Have been on Xeloda 5days. 2000mg bid and past few days intermittent chest and arm pain. I had check up at hospital, including a stress test which was all normal. Pain fells like muscle tightness and comes on after exertion.

    Reply

  • From this study (2 months ago):

  • 79 years old female started with 4 500mg pills 2x a day -- because of side effects cut back to 3 500 mg pills 2x a day

    Reply

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On eHealthMe, Xeloda (capecitabine) is often used for colon cancer. Find out below the conditions Xeloda is used for, how effective it is, and any alternative drugs that you can use to treat those same conditions.

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