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Review: could Xeloda cause Large intestine perforation?





Summary: Large intestine perforation is found among people who take Xeloda, especially for people who are male, 60+ old, have been taking the drug for < 1 month, also take medication Avastin, and have Rectal cancer.

We study 18,060 people who have side effects while taking Xeloda from FDA and social media. Among them, 54 have Large intestine perforation. Find out below who they are, when they have Large intestine perforation and more.

You are not alone: join a mobile support group for people who take Xeloda and have Large intestine perforation >>>

Xeloda

Xeloda has active ingredients of capecitabine. It is often used in colon cancer. (latest outcomes from Xeloda 18,174 users)

Large intestine perforation

Large intestine perforation (hole in large intestine) has been reported by people with rheumatoid arthritis, crohn's disease, high blood pressure, multiple sclerosis, hyperphosphataemia.(latest reports from Large intestine perforation 2,795 patients)

On Nov, 26, 2014: 18,060 people reported to have side effects when taking Xeloda. Among them, 54 people (0.30%) have Large Intestine Perforation.

Trend of Large intestine perforation in Xeloda reports

Time on Xeloda when people have Large intestine perforation * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years
Large intestine perforation60.00%37.14%2.86%0.00%0.00%0.00%0.00%

Age of people who have Large intestine perforation when taking Xeloda * :

0-12-910-1920-2930-3940-4950-5960+
Large intestine perforation0.00%0.00%0.00%0.00%0.00%23.08%38.46%38.46%

Severity of Large intestine perforation when taking Xeloda ** :

n/a

How people recovered from Large intestine perforation ** :

n/a

Top conditions involved for these people * :

  1. Rectal cancer (16 people, 29.63%)
  2. Neoplasm malignant (5 people, 9.26%)
  3. Rectal cancer metastatic (4 people, 7.41%)
  4. Nausea (4 people, 7.41%)
  5. Colon cancer metastatic (4 people, 7.41%)

Top co-used drugs for these people * :

  1. Avastin (26 people, 48.15%)
  2. Oxaliplatin (16 people, 29.63%)
  3. Elplat (8 people, 14.81%)
  4. Loxonin (6 people, 11.11%)
  5. Zocor (6 people, 11.11%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you have Large Intestine Perforation while taking Xeloda?

You are not alone! Join a mobile support group:
- support group for people who take Xeloda and have Large Intestine Perforation
- support group for people who take Xeloda
- support group for people who have Large Intestine Perforation

Drugs in real world that are associated with:

Could your condition cause:

Can you answer these questions (Ask a question):

  • Trouble breathing on xeloda
    (Asked by a 72 year old man who has Breathing Difficulty, and takes Xeloda)
    Been on 3000 mil of xeloda for 5 treatments. Last one at start of 7 days off breathing just got more difficult to walk from room to room
  • My father take xeloda and have muscle pain which drug he can take ?
    (Asked by a 70 year old man who has Pain, and takes Xeloda )
    My father have secum adenocarcinoma and remove them with surgery now he take xeloda 500 2pill morning and 2 pill night but he had muscle pain.
  • How long before hair loss after starting on xeloda (1 answer)
    (Asked by a 75 year old woman who has Colon Cancer Stage Ii, and takes Xeloda)
    first time using this drug,was concerned about hair loss. Approximate time you should expect possible hair loss
  • Finding more tumore after 4 cycles of xeloda
    (Asked by a 43 year old woman who takes Xeloda)
    On 20/2/2013 my wife is a 42 years old with the diagnosis of locally advanced left breast cancer (T4b) & clinically positive left supraclavicular & axillary lymph nodes (N3) " invasive ductal carcinoma " . Immunophenotyping was +ve for ER & PR (4/8) , -ve for HER2 (1) with ki-67 =4% . She started ...
  • Is there a remedy for uti caused by side effect to xeloda
    (Asked by a 67 year old woman who has UTI, and takes Xeloda)
    My GP thinks that my symptoms of UTI may be as a result of taking Xeloda. Is there a remedy to cure it other than antibiotics

More questions for: Xeloda, Large intestine perforation

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NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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