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Review: could Xeloda cause Large intestine perforation?

Summary: Large intestine perforation is found among people who take Xeloda, especially for people who are 60+ old, have been taking the drug for < 1 month, also take medication Avastin, and have Rectal cancer. We study 18,063 people who have side effects while taking Xeloda from FDA and social media. Among them, 54 have Large intestine perforation. Find out below who they are, when they have Large intestine perforation and more.

You are not alone: join a support group for people who take Xeloda and have Large intestine perforation >>>

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Xeloda

Xeloda has active ingredients of capecitabine. It is often used in colon cancer. (latest outcomes from 18,177 Xeloda users)

Large intestine perforation

Large intestine perforation (hole in large intestine) has been reported by people with rheumatoid arthritis, crohn's disease, high blood pressure, multiple sclerosis, hyperphosphataemia. (latest reports from 2,795 Large intestine perforation patients)

On May, 22, 2015: 18,063 people reported to have side effects when taking Xeloda. Among them, 54 people (0.30%) have Large Intestine Perforation.

Trend of Large intestine perforation in Xeloda reports

Time on Xeloda when people have Large intestine perforation * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years
Large intestine perforation60.00%37.14%2.86%0.00%0.00%0.00%0.00%

Age of people who have Large intestine perforation when taking Xeloda * :

0-12-910-1920-2930-3940-4950-5960+
Large intestine perforation0.00%0.00%0.00%0.00%0.00%23.08%38.46%38.46%

Severity of Large intestine perforation when taking Xeloda ** :

n/a

How people recovered from Large intestine perforation ** :

n/a

Top conditions involved for these people * :

  1. Rectal cancer (16 people, 29.63%)
  2. Neoplasm malignant (5 people, 9.26%)
  3. Rectal cancer metastatic (4 people, 7.41%)
  4. Nausea (4 people, 7.41%)
  5. Colon cancer metastatic (4 people, 7.41%)

Top co-used drugs for these people * :

  1. Avastin (26 people, 48.15%)
  2. Oxaliplatin (16 people, 29.63%)
  3. Elplat (8 people, 14.81%)
  4. Loxonin (6 people, 11.11%)
  5. Zocor (6 people, 11.11%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Get connected: join our support group of Xeloda and large intestine perforation on

Do you have Large Intestine Perforation while taking Xeloda?

 

You are not alone! Join a support group on :
- support group for people who take Xeloda and have Large Intestine Perforation
- support group for people who take Xeloda
- support group for people who have Large Intestine Perforation

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More questions for: Xeloda, Large intestine perforation

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Comments from related studies:

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