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Review: could Xeloda cause Large intestine perforation?

Summary: Large intestine perforation could be caused by Xeloda, especially for people who are male, 60+ old, have been taking the drug for < 1 month, also take Avastin, and have Rectal cancer.

We study 18,051 people who have side effects while taking Xeloda from FDA and social media. Among them, 54 have Large intestine perforation. Find out below who they are, when they have Large intestine perforation and more.

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Xeloda

Xeloda (latest outcomes from 18,163 users) has active ingredients of capecitabine. It is often used in colon cancer.

Large intestine perforation

Large intestine perforation (hole in large intestine) (latest reports from 13,889 patients) has been reported by people with rheumatoid arthritis, crohn's disease, high blood pressure, multiple sclerosis, hyperphosphataemia.

On Apr, 11, 2014: 18,033 people reported to have side effects when taking Xeloda. Among them, 54 people (0.30%) have Large Intestine Perforation. They amount to 0.39% of all the 13,858 people who have Large Intestine Perforation on eHealthMe.

Trend of Large intestine perforation in Xeloda reports

Time on Xeloda when people have Large intestine perforation * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years
Large intestine perforation60.00%37.14%2.86%0.00%0.00%0.00%0.00%

Age of people who have Large intestine perforation when taking Xeloda * :

0-12-910-1920-2930-3940-4950-5960+
Large intestine perforation0.00%0.00%0.00%0.00%0.00%23.08%38.46%38.46%

Severity of Large intestine perforation when taking Xeloda ** :

n/a

How people recovered from Large intestine perforation ** :

n/a

Top conditions involved for these people * :

  1. Rectal cancer (16 people, 29.63%)
  2. Neoplasm malignant (5 people, 9.26%)
  3. Rectal cancer metastatic (4 people, 7.41%)
  4. Nausea (4 people, 7.41%)
  5. Colon cancer metastatic (4 people, 7.41%)

Top co-used drugs for these people * :

  1. Avastin (26 people, 48.15%)
  2. Oxaliplatin (16 people, 29.63%)
  3. Elplat (8 people, 14.81%)
  4. Zocor (6 people, 11.11%)
  5. Loxonin (6 people, 11.11%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Related topic: Xeloda, Large intestine perforation

You can also:

On eHealthMe, Xeloda (capecitabine) is often used for colon cancer. Find out below the conditions Xeloda is used for, how effective it is, and any alternative drugs that you can use to treat those same conditions.

What is Xeloda used for and how effective is it:

Other drugs that are used to treat the same conditions:

Could it be a symptom from a condition:

Drugs in real world that are associated with:

Could your condition cause it?

Comments from related studies:

  • From this study (7 days ago):

  • After two hours from taking Xeloda in the morning my glucose levels are extrememly high. In morning before Xedoda they were in the 100's

    Reply

  • From this study (2 months ago):

  • Swelling develops quickly and is usually accompanied by itching and occasional rash. Swelling begins to dissipate after 4-5 hours. It is totally random - two weeks without any swelling, then 3-4 days with itching and swelling at different sites.

    Reply

  • From this study (2 months ago):

  • Have some constipation with aching abdominal bloating, some stomach pain

    Reply

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NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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