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Review: could Zanaflex cause Suicide attempt?

Summary: Suicide attempt is found among people who take Zanaflex, especially for people who are female, 40-49 old, have been taking the drug for < 1 month, also take medication Neurontin, and have Pain.

We study 6,736 people who have side effects while taking Zanaflex from FDA and social media. Among them, 85 have Suicide attempt. Find out below who they are, when they have Suicide attempt and more.

You are not alone: join a support group for people who take Zanaflex and have Suicide attempt >>>



Zanaflex has active ingredients of tizanidine hydrochloride. It is often used in muscle spasms. (latest outcomes from 7,307 Zanaflex users)

Suicide attempt

Suicide attempt has been reported by people with depression, quit smoking, stress and anxiety, pain, bipolar disorder. (latest reports from 32,157 Suicide attempt patients)

On Mar, 10, 2015: 6,736 people reported to have side effects when taking Zanaflex. Among them, 85 people (1.26%) have Suicide Attempt.

Trend of Suicide attempt in Zanaflex reports

Time on Zanaflex when people have Suicide attempt * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years
Suicide attempt75.00%0.00%25.00%0.00%0.00%0.00%0.00%

Gender of people who have Suicide attempt when taking Zanaflex * :

Suicide attempt57.30%42.70%

Age of people who have Suicide attempt when taking Zanaflex * :

Suicide attempt0.00%0.00%0.00%7.04%19.72%56.34%16.90%0.00%

Severity of Suicide attempt when taking Zanaflex ** :


How people recovered from Suicide attempt ** :


Top conditions involved for these people * :

  1. Pain (21 people, 24.71%)
  2. Depression (18 people, 21.18%)
  3. Anxiety (16 people, 18.82%)
  4. Fibromyalgia (10 people, 11.76%)
  5. Multiple sclerosis (10 people, 11.76%)

Top co-used drugs for these people * :

  1. Neurontin (34 people, 40.00%)
  2. Oxycontin (26 people, 30.59%)
  3. Paxil (23 people, 27.06%)
  4. Klonopin (22 people, 25.88%)
  5. Flexeril (22 people, 25.88%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you have Suicide Attempt while taking Zanaflex?




You are not alone! Join a mobile support group on :
- support group for people who take Zanaflex and have Suicide Attempt
- support group for people who take Zanaflex
- support group for people who have Suicide Attempt

Drugs in real world that are associated with:

Could your condition cause:

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Recent Zanaflex related drug comparison:

NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.


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