Review: could Zantac cause Spinal Compression Fracture?


Spinal compression fracture is found among people who take Zantac, especially for people who are female, 60+ old , have been taking the drug for 10+ years, also take medication Zometa, and have Multiple myeloma . We study 40,701 people who have side effects while taking Zantac from FDA and social media. Among them, 178 have Spinal compression fracture. Find out below who they are, when they have Spinal compression fracture and more.

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Zantac has active ingredients of ranitidine hydrochloride. It is often used in gastroesophageal reflux disease. (latest outcomes from Zantac 47,959 users)

Spinal Compression Fracture

Spinal compression fracture (fracture due to spinal compression on bone) has been reported by people with osteoporosis, multiple myeloma, rheumatoid arthritis, high blood pressure, osteopenia (latest reports from 6,464 Spinal compression fracture patients).

On Oct, 18, 2016

40,701 people reported to have side effects when taking Zantac.
Among them, 178 people (0.44%) have Spinal Compression Fracture

Number of reports submitted per year:

Could Zantac cause Spinal compression fracture?

Time on Zantac when people have Spinal Compression Fracture *:

  • < 1 month: 0.0 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 50 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 50 %

Gender of people who have Spinal Compression Fracture when taking Zantac *:

  • female: 56.25 %
  • male: 43.75 %

Age of people who have Spinal Compression Fracture when taking Zantac *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.62 %
  • 30-39: 0.62 %
  • 40-49: 14.38 %
  • 50-59: 20.62 %
  • 60+: 63.75 %

Top conditions involved for these people *:

  • Multiple Myeloma (35 people, 19.66%)
  • Gastrooesophageal Reflux Disease (25 people, 14.04%)
  • Pain (17 people, 9.55%)
  • Osteoporosis (17 people, 9.55%)
  • Hypercalcaemia Of Malignancy (14 people, 7.87%)

Top co-used drugs for these people *:

  • Zometa (122 people, 68.54%)
  • Prednisone (74 people, 41.57%)
  • Lasix (69 people, 38.76%)
  • Aredia (65 people, 36.52%)
  • Dexamethasone (61 people, 34.27%)

Top other side effects for these people *:

  • Pain (124 people, 69.66%)
  • Back Pain (111 people, 62.36%)
  • Osteonecrosis Of Jaw (104 people, 58.43%)
  • Anxiety (96 people, 53.93%)
  • Asthenia (74 people, 41.57%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

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