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Review: could Zoloft cause Acid reflux?

Summary: Acid reflux could be caused by Zoloft, especially for people who are female, 40-49 old, have been taking the drug for 2 - 5 years, also take Prilosec, and have Depression.

We study 73,646 people who have side effects while taking Zoloft from FDA and social media. Among them, 128 have Acid reflux. Find out below who they are, when they have Acid reflux and more.

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Zoloft

Zoloft (latest outcomes from 77,961 users) has active ingredients of sertraline hydrochloride. It is often used in depression.

Acid reflux

Acid reflux (stomach acids rise up) (latest reports from 43,926 patients) has been reported by people with high blood pressure, osteoporosis, depression, pain, high blood cholesterol.

On Apr, 10, 2014: 73,518 people reported to have side effects when taking Zoloft. Among them, 128 people (0.17%) have Acid Reflux. They amount to 0.29% of all the 43,839 people who have Acid Reflux on eHealthMe.

Trend of Acid reflux in Zoloft reports

Time on Zoloft when people have Acid reflux * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years
Acid reflux0.00%4.76%9.52%0.00%47.62%23.81%14.29%

Age of people who have Acid reflux when taking Zoloft * :

0-12-910-1920-2930-3940-4950-5960+
Acid reflux2.78%0.00%4.63%8.33%13.89%25.00%22.22%23.15%

Severity of Acid reflux when taking Zoloft ** :

leastmoderateseveremost severe
Acid reflux0.00%47.06%52.94%0.00%

How people recovered from Acid reflux ** :

while on the drugafter off the drugnot yet
Acid reflux0.00%75.00%25.00%

Top conditions involved for these people * :

  1. Depression (15 people, 11.72%)
  2. Anxiety (15 people, 11.72%)
  3. Pain (11 people, 8.59%)
  4. Contraception (5 people, 3.91%)
  5. Nausea (5 people, 3.91%)

Top co-used drugs for these people * :

  1. Prilosec (25 people, 19.53%)
  2. Lipitor (19 people, 14.84%)
  3. Xanax (17 people, 13.28%)
  4. Zocor (16 people, 12.50%)
  5. Fosamax (13 people, 10.16%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Related topic: Zoloft, Acid reflux

You can also:

On eHealthMe, Zoloft (sertraline hydrochloride) is often used for depression. Find out below the conditions Zoloft is used for, how effective it is, and any alternative drugs that you can use to treat those same conditions.

What is Zoloft used for and how effective is it:

Other drugs that are used to treat the same conditions:

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Could your condition cause it?

Comments from related studies:

  • From this study (3 days ago):

  • Bringing up acid into throat. Painful 'lumpy/burning/squeezing/very painful' sensation in mid chest when swallowing food/drink or even just air. Constant dull burning discomfort in between swallowing.

    Reply

  • From this study (3 months ago):

  • Terrible acid reflux. Burping and lump in throat. It is affecting my COPD

    Reply

  • From this study (2 years ago):

  • marcus on Jun, 3, 2012:

    hi,i am a 36 y/o Caucasian male from australia.
    i have been taking sertraline (zoloft) and its generics for about 15 years.
    i noticed on occasions that if the tablet got wet, i would get heartburn. for example if scooping water from a tap to take medication.
    the tablet starts to break up and leaves a paste that when swallowed is really painful.
    it causes a heartburn type feeling all down the oesophagus to my gut. I think i may try putting the pills in capsules. i don't understand why the company that makes these pills hasn't already don't this. it is really painful and lasts about 30 minutes minimum.
    to help wash down this heartburn i have tried drinking lots of milk or soy milk and eating something to slough down the residue.
    it does work somewhat so i suggest that but it still leaves a little heartburn.
    I have it right now. actually... i just drank a whole lot of soy milk (one glass) and it feels a lot better.

    Reply

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