Zonisamide and Serotonin syndrome - from FDA reports


Serotonin syndrome is found among people who take Zonisamide, especially for people who are female, 30-39 old also take medication Gabapentin, and have Pelvic pain . We study 3,692 people who have side effects while taking Zonisamide from FDA. Among them, 14 have Serotonin syndrome. Find out below who they are, when they have Serotonin syndrome and more.

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Zonisamide has active ingredients of zonisamide. It is often used in epilepsy. (latest outcomes from Zonisamide 3,971 users)

Serotonin Syndrome

Serotonin syndrome (occurs when two drugs that affect the body's level of serotonin are taken together at the same time) has been reported by people with depression, pain, stress and anxiety, major depression, insomnia (latest reports from 9,744 Serotonin syndrome patients).

On Jan, 31, 2017

3,692 people reported to have side effects when taking Zonisamide.
Among them, 14 people (0.38%) have Serotonin Syndrome

Number of reports submitted per year:

Could Zonisamide cause Serotonin syndrome?

Gender of people who have Serotonin Syndrome when taking Zonisamide *:

  • female: 76.92 %
  • male: 23.08 %

Age of people who have Serotonin Syndrome when taking Zonisamide *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 23.08 %
  • 20-29: 0.0 %
  • 30-39: 76.92 %
  • 40-49: 0.0 %
  • 50-59: 0.0 %
  • 60+: 0.0 %

Top conditions involved for these people *:

  • Pelvic Pain (8 people, 57.14%)
  • Bipolar Disorder (4 people, 28.57%)
  • Abnormal Behaviour (3 people, 21.43%)
  • Urination - Painful (1 person, 7.14%)
  • Pain (1 person, 7.14%)

Top co-used drugs for these people *:

  • Prochlorperazine (9 people, 64.29%)
  • Gabapentin (9 people, 64.29%)
  • Levothyroxine Sodium (8 people, 57.14%)
  • Citalopram Hydrobromide (8 people, 57.14%)
  • Buspirone Hcl (8 people, 57.14%)

Top other side effects for these people *:

  • Urinary Tract Infection (4 people, 28.57%)
  • Rhabdomyolysis (4 people, 28.57%)
  • Renal Failure Acute (3 people, 21.43%)
  • Hyperhidrosis (2 people, 14.29%)
  • Mydriasis (1 person, 7.14%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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