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From FDA reports: Zyprexa and Serotonin syndrome

This is a study of Serotonin syndrome among people who take Zyprexa. The study analyzes: the time on Zyprexa when people have Serotonin syndrome, gender and age of these people, the severity of Serotonin syndrome, how they recovered, and common conditions and drugs used besides Zyprexa. In total 41,631 Zyprexa users are studied. The study is created by eHealthMe based on reports from FDA and is updated regularly.

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Zyprexa

Zyprexa has active ingredients of olanzapine. It is used in bipolar disorder, depression, bipolar i disorder, stress and anxiety, schizophrenia. Commonly reported side effects of Zyprexa include diabetes, weight increased, type 2 diabetes, high blood cholesterol, pancreatitis.

Serotonin syndrome

Serotonin syndrome has been reported by people with depression, pain, stress and anxiety, major depression, bipolar disorder.

On Jun, 16, 2013: 41,631 people reported to have side effects when taking Zyprexa. Among them, 140 people (0.34%) have Serotonin Syndrome.

Trend of Serotonin syndrome in Zyprexa reports

Time on Zyprexa when people have Serotonin syndrome * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years
Serotonin syndrome27.27%48.48%0.00%15.15%6.06%3.03%0.00%

Gender of people who have Serotonin syndrome when taking Zyprexa * :

FemaleMale
Serotonin syndrome61.08%38.92%

Age of people who have Serotonin syndrome when taking Zyprexa * :

0-12-910-1920-2930-3940-4950-5960+
Serotonin syndrome0.77%0.00%6.15%5.38%18.46%14.62%22.31%32.31%

Severity of Serotonin syndrome when taking Zyprexa ** :

n/a

How people recovered from Serotonin syndrome ** :

n/a

Top conditions involved for these people * :

  1. Depression (21 people, 15.00%)
  2. Bipolar disorder (17 people, 12.14%)
  3. Major depression (14 people, 10.00%)
  4. Anxiety (14 people, 10.00%)
  5. Schizophrenia (12 people, 8.57%)

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Top co-used drugs for these people * :

  1. Paxil (37 people, 26.43%)
  2. Clonazepam (28 people, 20.00%)
  3. Seroquel (24 people, 17.14%)
  4. Trazodone hcl (24 people, 17.14%)
  5. Lorazepam (22 people, 15.71%)

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* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

(If the study does not answer your question, use Personalized Q&A)

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Next: check whether serotonin syndrome is from a drug or a condition

You can also:

On eHealthMe, Zyprexa (olanzapine) is often used for bipolar disorder. Find out below the conditions Zyprexa is used for, how effective it is, and any alternative drugs that you can use to treat those same conditions.

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Related personalized Q&As (what is this?):

  • I have short term memory and i want to know if the medications i'm taking for bipolar is the reason for the memory loss.
    (for a 51 year old man who has Bipolar Disorder, and takes Lithium Carbonate, Geodon , Vistaril, Olanzapine)
    I used to have a pretty decent memory for a man who just turned 51. I recently been diagnosed 3 months ago and it's been a rough ride so far. The main thing that scares me that I will forget things or the idea that I won't remember portions of my life. Please advise. I need help.
  • Can olanzapine when prescribed off label cause you to become psychotic
    (for a 56 year old woman who has Anxiety And Depression, and takes Zyprexa)
    I have been taking trazodone for about 7 years and had no side effects. Then the doctor said that it was not working any more. I was losing some weight. He then put me on olanzapine and the side effects have become horrendous. I have only been taking olanzapine for 5 weeks and have been violentl ...

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NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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