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Review: Effexor xr side effects

In this review, we analyze Effexor xr side effects by the time on the drug, and age (0-60+) of the people who have side effects while taking Effexor xr. The review is based on 20,414 people who have side effects while taking Effexor xr from FDA and social media, and is updated regularly.

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What is Effexor xr

Effexor xr (latest outcomes from 21,869 users) has active ingredients of venlafaxine hydrochloride. It is often used in depression.

Other drugs that have the same active ingredients (venlafaxine hydrochloride): Effexor, Venlafaxine Hydrochloride.

On Dec, 31, 2014: 20,414 people who reported to have side effects when taking Effexor xr are studied

 outcomes

Most common side effects over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Drug Withdrawal Syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)Drug Withdrawal Syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)Drug Withdrawal Syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)Drug Withdrawal Syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)Drug Withdrawal Syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)Drug Withdrawal Syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)Drug Withdrawal Syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)Anxiety
Nausea (feeling of having an urge to vomit)DizzinessDizzinessDizzinessDizzinessDizzinessDepressionDepression
DizzinessNausea (feeling of having an urge to vomit)Nausea (feeling of having an urge to vomit)Headache (pain in head)Nausea (feeling of having an urge to vomit)Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)Drug IneffectiveNausea (feeling of having an urge to vomit)
Headache (pain in head)Headache (pain in head)Feeling AbnormalNausea (feeling of having an urge to vomit)Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)Nausea (feeling of having an urge to vomit)AnxietyDrug Withdrawal Syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
Suicidal IdeationAnxietyHeadache (pain in head)Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)AnxietyDepressionNausea (feeling of having an urge to vomit)Dizziness
Insomnia (sleeplessness)Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)DepressionHeadache (pain in head)Headache (pain in head)DizzinessPain
AnxietyFeeling AbnormalDepressionSuicidal IdeationDepressionAnxietyCryingDrug Ineffective
Feeling AbnormalSuicidal IdeationAnxietyFeeling AbnormalFeeling AbnormalFeeling AbnormalParaesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)Headache (pain in head)
DepressionDepressionSuicidal IdeationAnxietySuicidal IdeationInsomnia (sleeplessness)Suicidal IdeationFatigue (feeling of tiredness)
Condition AggravatedCondition AggravatedTremor (trembling or shaking movements in one or more parts of your body)Insomnia (sleeplessness)Insomnia (sleeplessness)CryingInsomnia (sleeplessness)Feeling Abnormal

Most common side effects by age * :

0-12-910-1920-2930-3940-4950-5960+
Drug Exposure During PregnancyConvulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)Suicidal IdeationDrug Withdrawal Syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)Drug Withdrawal Syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)Drug Withdrawal Syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)Nausea (feeling of having an urge to vomit)Fall
Maternal Drugs Affecting Foetus (chemical affecting the baby before birth taken by mother)AggressionSuicide AttemptNausea (feeling of having an urge to vomit)Nausea (feeling of having an urge to vomit)Nausea (feeling of having an urge to vomit)Drug Withdrawal Syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)Nausea (feeling of having an urge to vomit)
Drug Exposure Via Breast MilkStaring (a prolonged gaze or fixed look)Drug Withdrawal Syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)AnxietyDizzinessDepressionAnxietyAnxiety
IrritabilityWeight IncreasedAgitation (state of anxiety or nervous excitement)Suicidal IdeationAnxietyDizzinessDepressionDepression
Drug Withdrawal Syndrome Neonatal (prenatal nas is caused by discontinuation of drugs taken by the pregnant mother)Agitation (state of anxiety or nervous excitement)AggressionDizzinessDepressionAnxietyDizzinessFatigue (feeling of tiredness)
Feeding Disorder Neonatal (when newborn refuse to drink milk)Bipolar Disorder (mood disorder)Completed Suicide (act of taking one's own life)DepressionHeadache (pain in head)Headache (pain in head)Headache (pain in head)Drug Ineffective
Premature BabyBiteDepressionHeadache (pain in head)Suicidal IdeationParaesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)PainDrug Withdrawal Syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)Screaming (a long loud piercing cry)Nausea (feeling of having an urge to vomit)PainFatigue (feeling of tiredness)Drug IneffectiveDrug IneffectiveDyspnoea (difficult or laboured respiration)
Drug Withdrawal Syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)Suicidal BehaviourAngerFeeling AbnormalDrug IneffectiveFeeling AbnormalFatigue (feeling of tiredness)Dizziness
Tremor Neonatal (excited neuromuscular activity of newborns)DepressionCondition AggravatedSuicide AttemptParaesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)Suicidal IdeationInsomnia (sleeplessness)Headache (pain in head)

* Some reports may have incomplete information.

Browse Effexor xr side effects from A to Z:

Comments for this study:

tammy (3 years ago):

Iv been on effexor xr for 2 yrs. I am a female age 40 I tapered down from 150 Mg to 75 Mg over a two month period. Suddenly I developed severe agoraphobia. I had not ever had anything like this prior. I had some minor issues but nothing to this degree. I could not even take a shower. I felt so bad i was afraid to be seen in public for fear of someone seeing how sick I was and me winding up in a mental hospital. I did not want to be alone at all. My doctor added 5 then 10 Mg of lexapro it helped me but I had to stop the lex apro due to some side effectts. Now im back to square one. He offered ability to help me thrum until I can get off the effexor but I do not want to take a medicine like that. I don't understand why this has happened to me all I know is effexor has ruined mine and my family's life.
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tammy (3 years ago):

Iv been on effexor xr for 2 yrs. I am a female age 40 I tapered down from 150 Mg to 75 Mg over a two month period due to severe neck and shoulder tension that also was in the leer part of my head. Suddenly I developed severe agoraphobia and depression I had not ever had anything like this prior. My doctor added 5 then 10 Mg of lexapro it helped me but I had to stop the lexapro due to some side effects. Now im back to square one. He offered ability to help me thru until I can get off the effexor but I do not want to take a medicine like that. I don't understand why this has happened to me all I know is effexor has ruined mine and my family's life for now but I will get off this medicine somehow
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jodyjean0821 (3 years ago):

Effexor has horrible withdrawl symptoms!! Use caution when deciding to use this drug as I have experienced nausea, dizzyness, extreme tiredness, brain zaps, headaches when trying to wean off it! I would strongly recommend seeking an alternative to this drug!
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Are you taking Effexor xr?

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Can you answer these questions (Ask a question):

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    In 1999 I was prescribed 75mg time release Effexor. I took one pill and 4 hours later I became dizzy and it felt like a cold patch in the middle of my head. I ckecked my eyes as i started seeing too much light, my puples were dilated, all black. I managed to get up stairs and asked my mom to get me to hospital. I passed out, and as crazy as it sounds I had a vision of my nana. I knew I was gone.she told me to wake up. I wasn't breathing. I could hear my mom talking on the phone to 911saying I had no pulse. (She is an RN) the ambulance came and they couldn't find my blood pressure. I couldn't see very well. The ER doctors said to continue taking the meds and sent my home. I stopped taking the Effexor. I had the side effects for many months. I get aura migraines now and have extreme sensitivity to other drugs.
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    Ambien was prescribed after my sleep study showed severe sleep latency and awakening. In the five hours I slept I woke 85 times and had only 5 minutes of deep sleep. However, the doctors couldn't make a recommendation because they could detect no cause for the poor sleep pattern. My doctor offered Ambien and since I had obviously needed the help sleeping I took it. For the next 10 years I suffered incredible depression. For example I remember laying in bed staring at the ceiling with tears rolling into my ears but I was too tired to wipe them away and realizing that I wanted to die so badly but there was no way I could have done anything about it. The worst effects were the loss of consciousness and the verbal abuse that I heaped on my husband and son. An example of each : I actually had sex with my husband that I could not remember amd hundreds of other actions and discussions. My husband started asking every morning what I remembered of the night before. He could usually tell when I was Ambien-awake (his name for it) he said my eyes would get glassy and my voice cadence would be off. Unfortunately my oldest son was going from infant to 8 years old at this time and any ifraction or even without provocation I would scream horrible things in his face. I don't remember much of it but what I do remember causes me enormous regret. He went from a happy and active toddler to a terrified amd anxious pre-teen. We are still working through the effects of this behavior. Finally, after a surprise pregnancy (see example above) My baby was placed in NICU and I stayed at the Ronald McDonald House and my son and husband visited when they could. Somehow my Ambien prescription was stopped and so I began going through withdrawal but I had no idea what was going on. My vision became so blurred thqt I couldn't identify items unless they were very large and then only by colors. When I visited my son those several days in the NICU I couldn't walk straight and would try to aim myself toward my goal until I hit a wall and I would correct course. These things didn't bother me at all but the nurses in the NICU were with me nearly the entire day because they were afraid I would have a stroke or who knew. Finally, after discussing these symptoms we decided to gradually stop the medication. Thankfully, i didn't have any withdrawal symptoms then. I did feel like an incredibly heavy and black blanket had been lifted away. Ever since I have had very little trouble with depression despite the continuation of sleep disturbance and pain. On a scale from one to 10 for depression with 10 being committing suicide I think my 10 years on the medicine was probably an 8.5 (I desperately wanted to die) and since stopping the medication I don't think it has gone above a 4 and is usually a 2 or 3. I will spend the rest of my life trying to repair the damage my verbal abuse caused my oldest son and my husband. For 10 years they lived in fear of my rages if I had a bad episode with Ambien.
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On eHealthMe, Effexor Xr (venlafaxine hydrochloride) is often used for depression. Find out below the conditions Effexor Xr is used for, how effective it is, and any alternative drugs that you can use to treat those same conditions.

What is Effexor Xr used for and how effective is it:

Other drugs that are used to treat the same conditions:

Studies of common Effexor xr drug interactions:

Browse Effexor xr drug interactions with drugs from A to Z:

NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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