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Review: Imiquimod side effects

In this review, we analyze Imiquimod side effects by the time on the drug, gender and age (0-60+) of the people who have side effects while taking Imiquimod. The review is based on 137 people who have side effects while taking Imiquimod from FDA and social media, and is updated regularly.

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What is Imiquimod

Imiquimod (latest outcomes from 142 users) has active ingredients of imiquimod. It is often used in actinic keratosis.

Other drugs that have the same active ingredients (imiquimod): Aldara, Zyclara.

On Jul, 5, 2014: 137 people who reported to have side effects when taking Imiquimod are studied


Most common side effects over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Application Site PainApplication Site Painn/aUvulitisn/an/an/aPyrexia
NauseaApplication Site PruritusBack Pain
Application Site PruritusGastric Ulcer HaemorrhageDizziness
Application Site InflammationScabMyalgia
VomitingApplication Site ErythemaMalaise
Salivary Gland PainPainAsthenia
Application Site UlcerSkin DiscolourationErythema
Parotid Gland EnlargementApplication Site DischargeBasal Cell Carcinoma
Neutrophil Count DecreasedRashPain
Differential White Blood Cell Count AbnormalLip UlcerationNeoplasm Malignant

Most common side effects by gender * :

Application Site PainPyrexia
Differential White Blood Cell Count AbnormalAsthenia
Neutrophil Count DecreasedMalaise
RashBack Pain
Application Site PruritusRenal Tubular Necrosis
Application Site InflammationVomiting
Infected Skin UlcerMulti-organ Failure

Most common side effects by age * :

n/aPyrexiaSuicidal IdeationNeutrophil Count DecreasedPapilloma Viral InfectionPyrexiaApplication Site PainScab
SwellingMood SwingsDifferential White Blood Cell Count AbnormalSkin LesionDizzinessInfected Skin UlcerPain
Neoplasm SkinAggressionNauseaSquamous Cell CarcinomaAnuriaApplication Site InflammationRash
Skin InjurySalivary Gland PainBowen's DiseaseAstheniaDysuriaApplication Site Pain
Neoplasm MalignantParotid Gland EnlargementPain Of SkinRenal Tubular NecrosisApplication Site PruritusMyalgia
Disease ProgressionVomitingNail Growth AbnormalBack PainApplication Site UlcerPruritus
NauseaMulti-organ FailureGraft Versus Host DiseaseRenal Failure AcuteHypersensitivityApplication Site Erythema
VomitingPerirectal AbscessInfectionOropharyngeal PainHypotensionBasal Cell Carcinoma
HeadacheClostridial InfectionSkin PapillomaMalaiseVomitingApplication Site Pruritus
Pseudomonal SepsisAlopeciaCytomegalovirus ColitisErythemaPyrexia

* Some reports may have incomplete information.

Browse Imiquimod side effects from A to Z:

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Comments from related studies:

  • From this study (2 weeks ago):

  • Small warts when squeezed release a pus like substance.


  • From this study (3 weeks ago):

  • O&O on Jun, 11, 2014:

    Yes, pancreatitis is listed as one of those side-effects of Aldara which was "discovered" "after-market" - ie - after the drug was supposedly tested and approved as safe by the FDA.


    KC on Jul, 3, 2010:

    I used Aldara on my face, a tiny spot, five times a week for a total of 12 weeks. At week 9 I went to hospital with severe abdominal pain, thinking I had appendicitis. Five weeks later I have pain throughout my body, though it is slowly getting better. If you decide to use Aldara, BE AWARE that it can cause serious, horrible side effects. Don't be afraid to stop using it. Talk to your doctor. Do some quick searches and you'll discover how many people have suffered badly from its effects.


    mandi de silva on Oct, 4, 2010:

    can you please tell me if your severe abdominal pain post usage of aldara cream was ever diagnosed? I have acute/chronic pancreatitis following usage of aldara in 2001...looking to find how many other people may be having this same symptom. I have many more autoimmune problems after using aldara..pancreatitis is just one of many disabling adverse reactions from aldara cream


  • From this study (3 weeks ago):

  • O&O on Jun, 11, 2014:

    I am a lawyer in Ontario, Canada, and I am taking on a case for a patient who has been seriously injured through the use of Aldara. I believe I can get some public interest in this problem, and I am looking for others who have suffered serious side-effects from the use of Aldara, in Ontario, Canada. Regardless of whether you may be considering litigation or not, I would like to speak with you because I have a way to get this information into the public sphere but it is obviously important to demonstrate that this is a big problem and not just a one-off incident.


    Serafina on Mar, 22, 2014:

    48 yrs old, white/f/already have 12 yrs. of multiple co-morbidities including but not limited to; intractable pain & chronic idiopathic non-alcoholic pancreatitis & spinal arthritis and idiopathic bilateral lower limb lymphadema and so much more.
    I am so sorry you all had to go through this but I do very much hope that it helps you all to know that you have saved one patient from trying this garbage 'medicine'. Thank you, Thank YOU ALL SO, so very much, I will be informing my Dermatologist that we will be treating the basal cells WITHOUT Aldara aka Imiquimod 5%.


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More questions for: Imiquimod

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NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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