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Review: Mirena side effects

In this review, we analyze Mirena side effects by the time on the drug, and age (0-60+) of the people who have side effects while taking Mirena. The review is based on 62,603 people who have side effects while taking Mirena from FDA and social media, and is updated regularly.

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What is Mirena

Mirena (latest outcomes from 62,957 users) has active ingredients of levonorgestrel. It is often used in birth control.

Other drugs that have the same active ingredients (levonorgestrel): Norplant, Norplant System In Plastic Container, Norplant Ii, Levonorgestrel, Plan B, Plan B One-step, Skyla.

On Mar, 16, 2015: 62,603 people who reported to have side effects when taking Mirena are studied


Most common side effects over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Device ExpulsionDevice ExpulsionDevice ExpulsionDevice ExpulsionPregnancy With Contraceptive DeviceDevice DislocationPainDevice Expulsion
Device DislocationDevice DislocationVaginal Haemorrhage (vaginal bleeding)Pregnancy With Contraceptive DeviceDevice ExpulsionAmenorrhoea (absence of a menstrual period in a woman of reproductive age)Endometriosis (appearance of endometrial tissue outside the uterus and causing pelvic pain)Device Dislocation
Procedural PainVaginal Haemorrhage (vaginal bleeding)Pregnancy With Contraceptive DeviceVaginal Haemorrhage (vaginal bleeding)Amenorrhoea (absence of a menstrual period in a woman of reproductive age)Vaginal Haemorrhage (vaginal bleeding)Adenomyosis (presence of ectopic glandular tissue found in muscle)Vaginal Haemorrhage (vaginal bleeding)
Abdominal PainAbdominal PainDevice DislocationDevice DislocationDevice DislocationProcedural PainPeritoneal LesionPregnancy With Contraceptive Device
Uterine Perforation (accidental puncture of the uterus)Iucd ComplicationAbdominal PainAbdominal PainVaginal Haemorrhage (vaginal bleeding)DepressionPyrexia (fever)Amenorrhoea (absence of a menstrual period in a woman of reproductive age)
Iucd ComplicationUterine Perforation (accidental puncture of the uterus)PainPainAbdominal PainBreast Cancer FemaleProcedural PainAbdominal Pain
Uterine RuptureUterine RuptureGenital Haemorrhage (bleeding from genital)Iucd ComplicationEctopic Pregnancy With Intrauterine DevicePregnancy With Contraceptive DeviceAbdominal PainIucd Complication
Vaginal Haemorrhage (vaginal bleeding)PainIucd ComplicationAmenorrhoea (absence of a menstrual period in a woman of reproductive age)Abortion Spontaneous (naturally occurring miscarriage)AnxietyUterine Leiomyoma (uterine benign tumour derived from smooth muscle)Medical Device Complication
PainGenital Haemorrhage (bleeding from genital)Menorrhagia (an abnormally heavy bleeding and prolonged menstrual period at regular intervals)Pelvic PainUterine Perforation (accidental puncture of the uterus)Breast CancerVaginal Haemorrhage (vaginal bleeding)Abdominal Pain Lower
Complication Of Device InsertionAbdominal Pain LowerAmenorrhoea (absence of a menstrual period in a woman of reproductive age)Uterine Perforation (accidental puncture of the uterus)PainWeight IncreasedDevice ExpulsionGenital Haemorrhage (bleeding from genital)

Most common side effects by age * :

Drug Exposure During PregnancyAlopecia (absence of hair from areas of the body)Device ExpulsionDevice ExpulsionDevice ExpulsionDevice ExpulsionDevice ExpulsionDevice Dislocation
Premature BabyPainAbdominal PainDevice DislocationDevice DislocationVaginal Haemorrhage (vaginal bleeding)Vaginal Haemorrhage (vaginal bleeding)Abdominal Pain
Device ExpulsionHunger (increased appetite is when you want to eat much more often or in larger quantities than your body requires)Device DislocationVaginal Haemorrhage (vaginal bleeding)Vaginal Haemorrhage (vaginal bleeding)Device DislocationBreast CancerDevice Expulsion
DeathSkin Disorder (skin disease)Pregnancy With Contraceptive DevicePregnancy With Contraceptive DevicePregnancy With Contraceptive DeviceAbdominal PainDevice DislocationAbdominal Pain Lower
Intrauterine InfectionThyroid Disorder (thyroid diseases)Vaginal Haemorrhage (vaginal bleeding)Abdominal PainAbdominal PainProcedural PainProcedural PainUltrasound Breast Abnormal
Haemangioma Congenital (congenital noncancerous, abnormally dense collections of dilated small blood vessels that may occur in the skin or internal organs)Uterine Perforation (accidental puncture of the uterus)Amenorrhoea (absence of a menstrual period in a woman of reproductive age)Iucd ComplicationIucd ComplicationGenital Haemorrhage (bleeding from genital)Amenorrhoea (absence of a menstrual period in a woman of reproductive age)Uterine Cancer
Foetal Growth Retardation (a baby in the womb fails to grow at the expected rate during the pregnancy)White Blood Cell Count IncreasedAbdominal Pain LowerAmenorrhoea (absence of a menstrual period in a woman of reproductive age)Procedural PainAmenorrhoea (absence of a menstrual period in a woman of reproductive age)Breast Cancer FemaleVaginal Haemorrhage (vaginal bleeding)
Intra-uterine DeathFeeling AbnormalProcedural PainProcedural PainAmenorrhoea (absence of a menstrual period in a woman of reproductive age)Menorrhagia (an abnormally heavy bleeding and prolonged menstrual period at regular intervals)Genital Haemorrhage (bleeding from genital)Pruritus (severe itching of the skin)
Placental DisorderCystitis (inflammation of the wall of the bladder)Iucd ComplicationAbdominal Pain LowerUterine Perforation (accidental puncture of the uterus)Iucd ComplicationMenorrhagia (an abnormally heavy bleeding and prolonged menstrual period at regular intervals)Urticaria (rash of round, red welts on the skin that itch intensely)
Insomnia (sleeplessness)Headache (pain in head)PainUterine Perforation (accidental puncture of the uterus)PainHeadache (pain in head)Endometrial CancerRash (redness)

* Some reports may have incomplete information.

Browse Mirena side effects from A to Z:

Comments for this study:

Jenn (3 years ago):

Got Eirena inserted two weeks ago. Twenty minutes After insertion I blacked out while driving my chest tightened I couldn't breath I couldn't feel anything from the waist down my arms and head went numb and the EMS ended.up taking me to the ER. The doc there said I was experiencing anaphylactic shock. They gave me benadryl and I had no clue what was going on the entire time in the hospital. The doc wouldn't remove the IUD because it was too dangerous. In the past week and a half I've had a constant period cramping in my abdomin and legs and am ill as a hornet. My back aches as well as my feet. After I eat my chest tightens and I can't catch my breath. I can't walkg too much BC I her winded. I'm not overweight and I didn't feel like this before the IUD. Considering taking it out. Too many scary side affects.
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Klarice (5 years ago):

Have suffered from side effects including: hair loss, weight gain (25 pounds in 15 months), fatigue, moodiness, hypertension, TIA, indigestion, edema, tinnitus, abdominal pain radiating into right leg, Class II pap smear result, edema in face, edema in extremeties, cystic acne, hyperhydrosis, joint pain. 47 years old, no children, no prior medical or weight problems
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Rachel (5 years ago):

Mirena makes me feel pregnant all the time. I hate it. I'm so moody and exhausted all the time. I drink a ton of caffeinated beverages including energy drinks just to stay active. Now my inactivity has caused me to start gaining weight which is not like me. I have three children and I cannot go through life feeling this way!
I used to be so motivated and happy most of the time or at least only sad when I had a good reason! I'm drowning in these side effects.
I had actually gone to my family doctor because of how I have been feeling and I had some vision issues as well, and constant headaches. He found nothing wrong with me at all. Mentioned something about a brain tumor possibility and never ran that test.
I have to say that Mirena is probably to blame but I have not made the appointment to have it removed. I do not know what other options are covered by my insurance company.

Any birth control suggestions from anyone who previously used Mirena?
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How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Are you taking Mirena?




On eHealthMe, Mirena (levonorgestrel) is often used for birth control. Find out below the conditions Mirena is used for, how effective it is, and any alternative drugs that you can use to treat those same conditions.

What is Mirena used for and how effective is it:

Other drugs that are used to treat the same conditions:

Studies of common Mirena drug interactions:

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NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

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