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Review: Mirena side effects

In this review, we analyze Mirena side effects by the time on the drug, and age (0-60+) of the people who have side effects while taking Mirena. The review is based on 62,524 people who have side effects while taking Mirena from FDA and social media, and is updated regularly.

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What is Mirena

Mirena (latest outcomes from 62,876 users) has active ingredients of levonorgestrel. It is often used in birth control.

Other drugs that have the same active ingredients (levonorgestrel): Norplant, Norplant System In Plastic Container, Norplant Ii, Levonorgestrel, Plan B, Plan B One-step, Skyla.

On Jul, 21, 2014: 62,524 people who reported to have side effects when taking Mirena are studied


Most common side effects over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Device ExpulsionDevice ExpulsionDevice ExpulsionDevice ExpulsionPregnancy With Contraceptive DeviceDevice DislocationEndometriosisDevice Expulsion
Device DislocationDevice DislocationVaginal HaemorrhagePregnancy With Contraceptive DeviceDevice ExpulsionAmenorrhoeaAdenomyosisDevice Dislocation
Procedural PainVaginal HaemorrhagePregnancy With Contraceptive DeviceVaginal HaemorrhageAmenorrhoeaVaginal HaemorrhagePyrexiaVaginal Haemorrhage
Abdominal PainAbdominal PainDevice DislocationDevice DislocationDevice DislocationProcedural PainProcedural PainPregnancy With Contraceptive Device
Uterine PerforationIucd ComplicationAbdominal PainAbdominal PainVaginal HaemorrhageDepressionAbdominal PainAmenorrhoea
Iucd ComplicationUterine PerforationPainPainAbdominal PainBreast Cancer FemalePeritoneal LesionAbdominal Pain
Uterine RuptureUterine RuptureGenital HaemorrhageIucd ComplicationEctopic Pregnancy With Intrauterine DevicePregnancy With Contraceptive DevicePainIucd Complication
Vaginal HaemorrhageGenital HaemorrhageIucd ComplicationPelvic PainAbortion SpontaneousAnxietyVaginal HaemorrhageMedical Device Complication
PainPainMenorrhagiaAmenorrhoeaUterine PerforationBreast CancerUterine LeiomyomaAbdominal Pain Lower
Complication Of Device InsertionAbdominal Pain LowerAmenorrhoeaUterine PerforationPainWeight IncreasedDevice ExpulsionGenital Haemorrhage

Most common side effects by age * :

Drug Exposure During PregnancyAlopeciaDevice ExpulsionDevice ExpulsionDevice ExpulsionDevice ExpulsionDevice ExpulsionDevice Dislocation
Premature BabyPainAbdominal PainDevice DislocationDevice DislocationVaginal HaemorrhageVaginal HaemorrhageAbdominal Pain
Device ExpulsionHungerDevice DislocationVaginal HaemorrhageVaginal HaemorrhageDevice DislocationBreast CancerDevice Expulsion
DeathSkin DisorderPregnancy With Contraceptive DevicePregnancy With Contraceptive DevicePregnancy With Contraceptive DeviceAbdominal PainDevice DislocationAbdominal Pain Lower
Intrauterine InfectionThyroid DisorderVaginal HaemorrhageAbdominal PainAbdominal PainProcedural PainProcedural PainUltrasound Breast Abnormal
Haemangioma CongenitalUterine PerforationAmenorrhoeaIucd ComplicationIucd ComplicationGenital HaemorrhageAmenorrhoeaUterine Cancer
Foetal Growth RetardationWhite Blood Cell Count IncreasedAbdominal Pain LowerAmenorrhoeaProcedural PainAmenorrhoeaBreast Cancer FemaleVaginal Haemorrhage
Intra-uterine DeathFeeling AbnormalProcedural PainProcedural PainAmenorrhoeaMenorrhagiaGenital HaemorrhagePruritus
Placental DisorderCystitisIucd ComplicationAbdominal Pain LowerUterine PerforationIucd ComplicationMenorrhagiaUrticaria
InsomniaHeadachePainUterine PerforationPainHeadacheEndometrial CancerRash

* Some reports may have incomplete information.

Browse Mirena side effects from A to Z:

Comments for this study:

Jenn (2 years ago):

Got Eirena inserted two weeks ago. Twenty minutes After insertion I blacked out while driving my chest tightened I couldn't breath I couldn't feel anything from the waist down my arms and head went numb and the EMS ended.up taking me to the ER. The doc there said I was experiencing anaphylactic shock. They gave me benadryl and I had no clue what was going on the entire time in the hospital. The doc wouldn't remove the IUD because it was too dangerous. In the past week and a half I've had a constant period cramping in my abdomin and legs and am ill as a hornet. My back aches as well as my feet. After I eat my chest tightens and I can't catch my breath. I can't walkg too much BC I her winded. I'm not overweight and I didn't feel like this before the IUD. Considering taking it out. Too many scary side affects.
Reply the comment

Klarice (4 years ago):

Have suffered from side effects including: hair loss, weight gain (25 pounds in 15 months), fatigue, moodiness, hypertension, TIA, indigestion, edema, tinnitus, abdominal pain radiating into right leg, Class II pap smear result, edema in face, edema in extremeties, cystic acne, hyperhydrosis, joint pain. 47 years old, no children, no prior medical or weight problems
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Rachel (4 years ago):

Mirena makes me feel pregnant all the time. I hate it. I'm so moody and exhausted all the time. I drink a ton of caffeinated beverages including energy drinks just to stay active. Now my inactivity has caused me to start gaining weight which is not like me. I have three children and I cannot go through life feeling this way!
I used to be so motivated and happy most of the time or at least only sad when I had a good reason! I'm drowning in these side effects.
I had actually gone to my family doctor because of how I have been feeling and I had some vision issues as well, and constant headaches. He found nothing wrong with me at all. Mentioned something about a brain tumor possibility and never ran that test.
I have to say that Mirena is probably to blame but I have not made the appointment to have it removed. I do not know what other options are covered by my insurance company.

Any birth control suggestions from anyone who previously used Mirena?
Reply the comment

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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Comments from related studies:

  • From this study (3 days ago):

  • I DO NOT recommend this device for ANYONE. I have had it for 13 months and it has completely changed every aspect of my life. All of my symptoms began around the 12-month mark except the excess vaginal secretions and odor which began almost instantly. I also blacked out for the first time in my ife while using Mirena which was the most terrifying experience I have ever had.

    It does prevent pregnancy but it is ruining my physical and mental health. I hope to have it removed soon.
    Hopefully this will help anyone out there in my situation. You don't have to take my word for it either. Research it on your own.


    Lisa on Mar, 9, 2013:

    I am 34 yr old female who chose to have the IUD placed for painful/heavy periods after having side effects from oral birth control. I had it placed 3 months ago. Since then I have had severe mood swings ranging from anger/aggitation to severe depression. I have gain 15 pounds (in 3 months), all in my abdomen- I look 6-7 months pregnant and no longer fit in any of my pants. I have severe headaches from the moment I wake up until I go to bed- to the point it feels like my head will explode- I take 3 aleve daily and that does nothing for the pain. I have no sex drive, and started having vaginal dryness- for which I was prescibed a vaginal estrogen cream.When the IUD was placed, I bled for almost the whole 3 months to the point I am anemic. I have changed NOTHING in my lifestyle since having the Mirena placed- I am active, work out 3-4 days a week, eat healthy. So, since having the Mirena placed I am on Iron for anemia, been on 2 different anti-depressants, have a vaginal cream. I have called my Dr who said all these side effects are 'normal'. It is not NORMAL for me- I am NOT the same person I was only 3 months ago. I am having this taken out as soon as possible. I am a nurse, and thought I researched this enough, until I started reading these blogs and see how many women have had the same side effects. Some women have had none. I STRONGLY encourage any woman to read more than what the medical and IUD websites state- read what real women are feeling.


    Mandy on Mar, 10, 2013:

    I have been having some of the same effects I informed my OB/GYN that I would probly want top have it removed. They told me that the insurance said when they paid for it I would have to try it for six months.I didn't remember them telling me that nore did I sign an agreement. When I got upset about this they sent me a letter that they dropped me as a patient. Now how am I supposed to get this thing out?


    Vee on May, 30, 2014:

    Hello I'm 45 years old and electively requested IUD. I have now had Merena for 2.5 months or so and I'm having severe joint pain in many parts of body and bone pains that I never had prior to the IUD. It is 5/30/14 and I'm currently trying to contact my MD to have this removed!!! It's making me sick. ;( ;( I hope this pain goes away once removed. Has anyone pain resided?? I'm regretting that I am using the Merina now.


    Vee on May, 30, 2014:

    I should add I have also gained a,lot of stomachs weight!!! This med should be banned my body is not right!! Aches all over


    Maria on Jun, 2, 2013:

    I had my mirena put in 11 months ago for horrible cramps and heavy periods. I started having breast tenderness, severe mood swings, then milky nipple drainage. I was also having pregnancy symptoms. I reported ithese symptoms to my object/gyn and dismissed them. I was pissed. I took matters into my own hand. I consulted a homeopathic doctor. I take some supplements from natures sunshine called liver balance and proactizyme. I feel sooooooo much better. If i deviate from the amount im supposed to take all the symptoms come back. Good luck to you. Know there is hope for feeling better.


    Cat on Jun, 20, 2014:

    I am 50 years of age now but had a Mirena fitted at the age of 46 after my GP suggested I should go off the contraceptive pill. I have always had menstral problems, heavy periods and pain etc. but whilst I was on the pill everything was manageable. My GP suggested a Mirena to control my periods so I had one fitted. For the first couple of months I noticed only slight side affects I.e. mood swings, and I always had this feeling that something wasn't right, like I had something inside me that shouldn't be there. After 3 months I started to notice I was having difficulty turning taps on and gripping things with my hands. It cam eon quite suddenly and within a month of the first of those symptoms, I really started to worry that I would be crippled with arthritis in my hands within a few months. I spent time on web sites and found a few stories of people with these type of side affects, so after much encouragement from family decided to go and have my GP remove the Mirena. Best thing I ever did, and within 2 weeks my arthritis was completely gone. Don't know why or what caused it, but deep down I think it was the Mirena. It doesnt stop there though. The Mentral problems I was having were manageable, but sine then they are out of control and I have now been diagnosed with Andeomyosis. I had a pelvic ultrasound when the Mirena was fitted and it was not found then, but now I have it. Again dont know what's caused it, but things have not been the same for me since that Mirenda was fitted. I am sure there are many women out there who don't have these issues, but I think something must be done to warn women these types of side affects can happen, and the impact to their quality of life and emotional well being is being compromised.


    Tiffany G on Jun, 27, 2014:

    Thank you for posting that! I am 30 & had the murena put in 2 1/2 weeks ago & just had it removed yesterday. I couldn't even wait the three months that it so adversely affected me. My doctor wanted me to wait it out & boy am I glad I didn't!!! I don't normally suffer from depression, but I'd feel depressed or outraged for no reason,loss of interest in sex & exercise have headaches, abdominal pain, odor & over the weekend I contracted seborrhic dermatitis & had to have an anti fungal cream prescribed! The doctor did not think all these symptoms were caused by the IUD, but I know my body & it was feeling pretty amazing up until I got it put in. Upon waking up with out it today, I feel amazing & miraculously the rash is disappearing... hmm & I know it isn't just from the cream helping! So fine, an IUD might works for some, but I've seen a lot more who it works against. Have doubts? Look & feel like crap? Do yourself a favour & get it removed! A stupid contraception device shouldn't run your life or make you feel miserable! It's NOT worth risking your health, like I did.


    Tiffany G on Jun, 27, 2014:

    If you still have your insurance, I would either find a new OB or go to the emergency room! If your having issues, I strongly encourage you to seek help in getting it out! I will keep you in my prayers!


    Tiffany G on Jun, 27, 2014:

    YES!! I would be restless all night because my joints in my legs felt as though I had severe arthritis & I'm only 30! I read on the murena IUD webpage, that you can get arthritic-like symptoms... since I had it removed those pains have ceased.


    Tiffany G on Jun, 27, 2014:

    I sincerely agree! & I see way too many doctors dismiss these problems & build the murena up to be something of a miracle! Yeah... a miracle I didn't loose my mind while I was on it... something must be done to spread more awareness. Also, I believe doctors don't warn us enough about side effects. Almost like they want us to believe there are none or when we get them, they want us to think something else is causing it when we all know by our women intuition that it is the IUD!! Lol


  • From this study (2 weeks ago):

  • I have had the mirena coil for 2 years my thyroid growth appeared after 6 months of fitting. I have 3 growths on both sides one large two very small


  • From this study (2 weeks ago):

  • Sharp pains under rt armpit comes and goes. Breast tenderness in both breasts.


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    Hi , I was on mirena @ six weeks post delivery of my second sons birth in August of 2011. In march of 2013 I felt extremely tired , sluggish , like I was sick . I also was experiencing tachycardia and fever . I went in to docs and he said I had a respiratory infection and sent me home with an inhale ...

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    Was healthy 31yrway old with 3mothe baby when iritis began. It lasted nearly 15moas never fully healing before flaring again. Otho considered Methotrexate it was so bad and life altering buying was breast feeding. Maybe could have treated differently if not nursing but with my baby's GI issues breas ...

  • Placenta previa after having the mirena iud
    I had the Mirena implant from 2006 to 2011 after my 2nd child. After having it removed my husband and I got pregnant in August 2013. When I was 13 weeks I started bleeding and week to the emergency room. Upon further treatment the doctor concluded that I had a threatened abortion caused by a small ...

More reviews for: Mirena

On eHealthMe, Mirena (levonorgestrel) is often used for birth control. Find out below the conditions Mirena is used for, how effective it is, and any alternative drugs that you can use to treat those same conditions.

What is Mirena used for and how effective is it:

Other drugs that are used to treat the same conditions:

Studies of common Mirena drug interactions:

Browse Mirena drug interactions with drugs from A to Z:

NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

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