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Review: Nexplanon side effects

In this review, we analyze Nexplanon side effects by the time on the drug, and age (0-60+) of the people who have side effects while taking Nexplanon. The review is based on 497 people who have side effects while taking Nexplanon from FDA and social media, and is updated regularly.

You are not alone: join a mobile support group for people who have Nexplanon side effects >>>

What is Nexplanon

Nexplanon (latest outcomes from 529 users) has active ingredients of etonogestrel. It is often used in birth control.

Other drugs that have the same active ingredients (etonogestrel): Implanon.

On Oct, 25, 2014: 497 people who reported to have side effects when taking Nexplanon are studied


Most common side effects over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Medical Device ComplicationMaternal Exposure During PregnancyMedical Device ComplicationPregnancy With Implant ContraceptiveVaginal Odourn/an/aMedical Device Complication
Implant Site PainPregnancy With Implant ContraceptiveAbortion SpontaneousAbortion SpontaneousDry MouthPregnancy With Implant Contraceptive
Implant Site SwellingAbortion SpontaneousPregnancy With Implant ContraceptiveMaternal Exposure During PregnancyRash GeneralisedMaternal Exposure During Pregnancy
Complication Of Device InsertionPremature DeliveryMotor DysfunctionConstipationUrticaria ChronicAbortion Spontaneous
Device ExpulsionImplant Site PainHypokinesiaPregnancy Test False PositiveAnxietyEpilepsy
Implant Site PruritusContusionMaternal Exposure During PregnancyHaemorrhageFlank PainImplant Site Pain
HypersensitivityExcessive Granulation TissuePanic AttackGroin PainEczemaMetrorrhagia
UrticariaErythemaDyspnoeaDepressed MoodLow Back PainComplication Of Device Insertion
Implant Site ErythemaMenorrhagiaPalpitationsHeadacheApplication Site RashConvulsion
Swelling FaceErysipelasParaesthesiaSkin NecrosisMenstrual Periods - Heavy, Prolonged, Or IrregularMenorrhagia

Most common side effects by age * :

Premature Babyn/aEpilepsyPregnancy With Implant ContraceptivePregnancy With Implant ContraceptiveCerebral Infarctionn/an/a
Maternal Drugs Affecting FoetusConvulsionMaternal Exposure During PregnancyMaternal Exposure During PregnancyLoss Of Employment
Pregnancy With Implant ContraceptiveAbortion SpontaneousAbortion InducedDizziness
Maternal Exposure During PregnancyPremature DeliveryDrug IneffectiveInsomnia
Condition AggravatedPruritusErysipelasDepression
Abortion SpontaneousParaesthesiaImplant Site ErythemaHeadache
VomitingVision BlurredHeadacheHaematoma
Implant Site ReactionPyrexiaAbortion MissedProcedural Pain
LacerationConstipationDevice DislocationParaesthesia
FibromyalgiaAnxietyStaphylococcal InfectionImplant Site Haematoma

* Some reports may have incomplete information.

Browse Nexplanon side effects from A to Z:

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Are you taking Nexplanon?

Comments from related studies:

  • From this study (4 days ago):

  • Flank pain gets worse when stressed


  • From this study (1 week ago):

  • Diagnosed with pid and severe cramping occuring


  • From this study (4 weeks ago):

  • I have had the Nexplanon implant for 6 weeks; prior to the implant i had been taking oral birth control pills for 7 years with perfectly clear skin. I had a mild reaction on my face within the first 4 days of having the implant but it went away after 7 days. For the next 2 1/2 weeks my skin was beautiful and clear. On the week i was supposed to start my cycle, instead of getting it, i received a break out on my forehead and cheek area. No form of topical medication eased the blemishes, although they never came to head and weren't that noticeable. On the day my cycle normally would have ended, i felt a deep pain in my lower chin but no blemishes had surfaced. On the 2nd day 3 small bumps had formed and were very painful but again not very noticeable or red. On the third day, they were very painful, itchy, red, and swollen but still no head. I called the NP who said it was more than likely cystic acne caused by the nexplanon implant. We are going to tdy oral antibiotics to see if it helps ease the pain and swelling and clears up my face. Today, on the fourth day it hasn't gotten any worse but is still extremely painful. Im hoping the Minocycline antibiotics work; otherwise the implant is coming out immediately. It just isn't worth having horrible acne.


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On eHealthMe, Nexplanon (etonogestrel) is often used for birth control. Find out below the conditions Nexplanon is used for, how effective it is, and any alternative drugs that you can use to treat those same conditions.

What is Nexplanon used for and how effective is it:

Other drugs that are used to treat the same conditions:

Studies of common Nexplanon drug interactions:

Browse Nexplanon drug interactions with drugs from A to Z:

NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

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