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Review: Nexplanon side effects

In this review, we analyze Nexplanon side effects by the time on the drug, and age (0-60+) of the people who have side effects while taking Nexplanon. The review is based on 487 people who have side effects while taking Nexplanon from FDA and social media, and is updated regularly.

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What is Nexplanon

Nexplanon (latest outcomes from 513 users) has active ingredients of etonogestrel. It is often used in birth control.

Other drugs that have the same active ingredients (etonogestrel): Implanon.

On Aug, 22, 2014: 487 people who reported to have side effects when taking Nexplanon are studied


Most common side effects over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Medical Device ComplicationMaternal Exposure During PregnancyMedical Device ComplicationPregnancy With Implant ContraceptiveRash Generalisedn/an/aMedical Device Complication
Implant Site PainPregnancy With Implant ContraceptiveAbortion SpontaneousAbortion SpontaneousApplication Site RashPregnancy With Implant Contraceptive
Implant Site SwellingAbortion SpontaneousPregnancy With Implant ContraceptiveMaternal Exposure During PregnancyPseudogoutMaternal Exposure During Pregnancy
Complication Of Device InsertionPremature DeliveryParaesthesiaConstipationUrticaria ChronicAbortion Spontaneous
Implant Site PruritusImplant Site PainHypokinesiaPregnancy Test False PositiveDry MouthEpilepsy
Device ExpulsionExcessive Granulation TissueMaternal Exposure During PregnancyHaemorrhageLow Back PainImplant Site Pain
UrticariaMenorrhagiaPanic AttackGroin PainAnxietyMetrorrhagia
HypersensitivityContusionDyspnoeaDepressed MoodMenstrual Periods - Heavy, Prolonged, Or IrregularComplication Of Device Insertion
Implant Site ErythemaErythemaPalpitationsHeadacheBpdMenorrhagia
Swelling FaceHeadacheMotor DysfunctionSkin NecrosisMuscle SpasmsUnintended Pregnancy

Most common side effects by age * :

Premature Babyn/aEpilepsyPregnancy With Implant ContraceptiveMaternal Exposure During PregnancyCerebral Infarctionn/an/a
Maternal Drugs Affecting FoetusConvulsionMaternal Exposure During PregnancyPregnancy With Implant ContraceptiveLoss Of Employment
Pregnancy With Implant ContraceptiveAbortion SpontaneousErysipelasDizziness
Maternal Exposure During PregnancyPremature DeliveryAbortion InducedInsomnia
Condition AggravatedPruritusDrug IneffectiveDepression
Abortion SpontaneousPyrexiaAbortion MissedHaematoma
FibromyalgiaVision BlurredImplant Site ErythemaProcedural Pain
LacerationConstipationDevice DislocationParaesthesia
Implant Site ReactionAngioedemaErythemaImplant Site Haematoma

* Some reports may have incomplete information.

Browse Nexplanon side effects from A to Z:

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Comments from related studies:

  • From this study (2 months ago):

  • Unsure if diarrhea is from new implanon replacement, or some other condition or parasite.


  • From this study (2 months ago):

  • Eyes would begin watering within ten minutes of standing after waking up. They would water to the point where tears would stream down my face for 10-20 minutes; once this stopped, the symptom wouldn't return again until the next morning. Eyes would rarely begin watering before standing or sitting. Symptom went away after dropping dosage from 50mg to 25mg.


  • From this study (3 months ago):

  • My daughter has had severe hair loss fron taking this medication along with very irregular cycles.


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On eHealthMe, Nexplanon (etonogestrel) is often used for birth control. Find out below the conditions Nexplanon is used for, how effective it is, and any alternative drugs that you can use to treat those same conditions.

What is Nexplanon used for and how effective is it:

Other drugs that are used to treat the same conditions:

Studies of common Nexplanon drug interactions:

Browse Nexplanon drug interactions with drugs from A to Z:

NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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