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Review: Pristiq side effects

In this review, we analyze Pristiq side effects by the time on the drug, and age (0-60+) of the people who have side effects while taking Pristiq. The review is based on 13,725 people who have side effects while taking Pristiq from FDA and social media, and is updated regularly.

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What is Pristiq

Pristiq (latest outcomes from 15,546 users) has active ingredients of desvenlafaxine succinate. It is often used in depression.

On Sep, 2, 2014: 13,725 people who reported to have side effects when taking Pristiq are studied


Most common side effects over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
NauseaDrug Withdrawal SyndromeDrug Withdrawal SyndromeDrug Withdrawal SyndromeNauseaFatigueAnorgasmiaNausea
HeadacheNauseaDizzinessDizzinessDizzinessDepressionHair Loss In WomenDrug Ineffective
DizzinessDizzinessHeadacheAnxietyWithdrawal SyndromeDrug Withdrawal SyndromePtsdHeadache
InsomniaHeadacheNauseaNauseaCryingOvarian CystTaste DisturbanceDizziness
Drug Withdrawal SyndromeDrug IneffectiveInsomniaFeeling AbnormalFeeling AbnormalTinnitusRestlessnessInsomnia
AnxietyInsomniaAnxietyDepressionHeadacheAngerElevated Liver EnzymesAnxiety
Feeling AbnormalFeeling AbnormalParaesthesiaHeadacheDrug Withdrawal SyndromeCryingFatigueFatigue
FatigueAnxietyHyperhidrosisDrug IneffectiveFatigueThrombocytopenic PurpuraVomitingDepression
Drug IneffectiveDepressionIrritabilityFatigueMalaiseSleepyNail Growth AbnormalFeeling Abnormal
DiarrhoeaCondition AggravatedFatiguePainPainNightmareBlood UrineDrug Withdrawal Syndrome

Most common side effects by age * :

Schizoid Personality DisorderBlood Test AbnormalSuicidal IdeationNauseaNauseaNauseaNauseaNausea
SomnambulismAccidental OverdoseTremorHeadacheDizzinessHeadacheHeadacheDrug Ineffective
Psychomotor HyperactivityHeart Rate DecreasedHeadacheDizzinessHeadacheDizzinessDrug IneffectiveFatigue
Obsessive-compulsive DisorderAccidental Drug Intake By ChildInsomniaAnxietyAnxietyInsomniaInsomniaInsomnia
Learning DisabilityPlatelet Count IncreasedNauseaFatigueDrug Withdrawal SyndromeAnxietyDizzinessDizziness
Suicidal IdeationSinus TachycardiaSuicide AttemptDrug Withdrawal SyndromeDepressionDrug IneffectiveAnxietyCondition Aggravated
TicElectrocardiogram T Wave AbnormalDepressionDepressionInsomniaFatigueFatigueHeadache
Visual ImpairmentBlood Alkaline Phosphatase IncreasedFeeling AbnormalFeeling AbnormalDrug IneffectiveDrug Withdrawal SyndromeDepressionAnxiety
Urinary IncontinenceHeart Rate IncreasedVomitingInsomniaFatigueFeeling AbnormalFeeling AbnormalDepression
Tourette's DisorderDizzinessCondition AggravatedFeeling AbnormalDepressionHyperhidrosisFeeling Abnormal

* Some reports may have incomplete information.

Browse Pristiq side effects from A to Z:

Comments for this study:

Breen123 (3 years ago):

I just stated it 4 days ago,but I have heard 2 to 3 weeks.
Reply the comment

Francesca (4 years ago):

I have been on pristiq for two weeks 50mg. I don't feel any change or improvement. Can someone
advise me as to how long does it take to actually
notice an improvement? Previously i was on paxil
20mg. which made me feel like a detached person
could not stand that feeling.
Reply the comment

Kevin Haren (4 years ago):

Does Pristiq have a false positive urinalysis effect for methadone.
Reply the comment

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Comments from related studies:

  • From this study (4 days ago):

  • I get diarrhoea only at night time. I take Endep only at night... and Lyrica 150mg at night (75mg in the morning)... and the Pristiq in the morning.


  • From this study (2 weeks ago):

  • I have Raynaud's syndrome, but even while in the office, my arms feel like they are immersed in ice water; my right leg will periodically "buckle" and wobble at the knee while I'm standing at a kitchen counter getting my food ready; my alarm goes off at 6:30, and about 2 days during the week, I hit the snooze button the max # of times and am late for work


    Sara on Aug, 19, 2014:

    I have sydenhams, dystonia and raynards. I have all from rhuematic fever, once you get one autoimmune disease my specialist says its not unusual to get others... the only thing that helps is living in Spain and in the winter gloves and socks!


  • From this study (3 weeks ago):

  • I have to add the elbow pain started after using a heavy reciprocating saw.
    The leg pain started after running a 10K. Went to ortho dr. Had physical therapy for hip flexor. now have pretty severe hip and leg pain but running
    again. ...but freaking out after reading about pristiq and joint pain. I went on and off the pristiq.
    Stopped it about a week ago. Didn't help....single, long travel for job, son who is schizophrenic,
    Financially recovering from a 2 year unemployment period. Fix all that and I wouldn't be depressed!


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You may be interested at these reviews (what is this?):

  • Higher than a kite, and dumber than one of those saying i can no longer remember!
    I told my shrink I didn't want to try anymore antidepressants... that they make me crazy-stupid(pristiq), crazy-nympho(wellbutrin), or crazy-sloth(lexapro). I have complex ptsd, did, and gad. I really don't want to take anything... I just want to work out, eat right, and try to put myself back on tr ...

  • Pristiq, epilim, sifrol, immovane, valium, mobic
    I started out with mild burnout depression in 2009 and was put on a low dose of Lexapro, which picked me up fantastically. I had been given low (2mg) Valium before for muscle relaxant purposes due to my scoliosis complications. Both these worked well. Then in 2010 I was drugged and raped and almo ...

  • Stopping pristiq for my memory
    I have been on Pristiq for 3 years. My short term memory loss is a great concern to me. I am 45 and I have questioned my doctor and given my concerns to the point she referred me to a neurologist but said it was not the Pristiq. There is no other drugs I am taking or have taken to cause this proble ...

More reviews for: Pristiq

On eHealthMe, Pristiq (desvenlafaxine succinate) is often used for depression. Find out below the conditions Pristiq is used for, how effective it is, and any alternative drugs that you can use to treat those same conditions.

What is Pristiq used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

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