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Review: Pristiq side effects

In this review, we analyze Pristiq side effects by the time on the drug, and age (0-60+) of the people who have side effects while taking Pristiq. The review is based on 13,711 people who have side effects while taking Pristiq from FDA and social media, and is updated regularly.

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What is Pristiq

Pristiq (latest outcomes from 15,528 users) has active ingredients of desvenlafaxine succinate. It is often used in depression.

On Jul, 22, 2014: 13,713 people who reported to have side effects when taking Pristiq are studied


Most common side effects over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
NauseaDrug Withdrawal SyndromeDrug Withdrawal SyndromeDrug Withdrawal SyndromeNauseaFatigueAnorgasmiaNausea
HeadacheNauseaDizzinessDizzinessDizzinessDepressionHair Loss In WomenDrug Ineffective
DizzinessDizzinessHeadacheAnxietyWithdrawal SyndromeDrug Withdrawal SyndromePtsdHeadache
InsomniaHeadacheNauseaFeeling AbnormalCryingOvarian CystTaste DisturbanceDizziness
Drug Withdrawal SyndromeDrug IneffectiveInsomniaNauseaFeeling AbnormalTinnitusRestlessnessInsomnia
AnxietyInsomniaAnxietyDepressionHeadacheFatigue - ChronicElevated Liver EnzymesAnxiety
Feeling AbnormalFeeling AbnormalParaesthesiaHeadacheDrug Withdrawal SyndromeCryingFatigueFatigue
FatigueAnxietyHyperhidrosisDrug IneffectiveMalaiseAngerVomitingDepression
Drug IneffectiveDepressionIrritabilityPainFatigueHivesNail Growth AbnormalFeeling Abnormal
DiarrhoeaCondition AggravatedFatigueFatiguePainNightmareBlood UrineDrug Withdrawal Syndrome

Most common side effects by age * :

Schizoid Personality DisorderBlood Test AbnormalSuicidal IdeationNauseaNauseaNauseaNauseaNausea
SomnambulismAccidental OverdoseTremorHeadacheDizzinessHeadacheHeadacheDrug Ineffective
Psychomotor HyperactivityHeart Rate DecreasedHeadacheDizzinessHeadacheDizzinessDrug IneffectiveFatigue
Obsessive-compulsive DisorderAccidental Drug Intake By ChildInsomniaAnxietyAnxietyInsomniaInsomniaInsomnia
Learning DisabilityPlatelet Count IncreasedNauseaFatigueDrug Withdrawal SyndromeAnxietyDizzinessDizziness
Suicidal IdeationSinus TachycardiaSuicide AttemptDrug Withdrawal SyndromeDepressionDrug IneffectiveAnxietyCondition Aggravated
TicElectrocardiogram T Wave AbnormalDepressionDepressionInsomniaFatigueFatigueHeadache
Visual ImpairmentBlood Alkaline Phosphatase IncreasedFeeling AbnormalFeeling AbnormalDrug IneffectiveDrug Withdrawal SyndromeDepressionAnxiety
Urinary IncontinenceHeart Rate IncreasedVomitingInsomniaFatigueFeeling AbnormalFeeling AbnormalDepression
Tourette's DisorderDizzinessCondition AggravatedFeeling AbnormalDepressionHyperhidrosisFeeling Abnormal

* Some reports may have incomplete information.

Browse Pristiq side effects from A to Z:

Comments for this study:

Breen123 (3 years ago):

I just stated it 4 days ago,but I have heard 2 to 3 weeks.
Reply the comment

Francesca (4 years ago):

I have been on pristiq for two weeks 50mg. I don't feel any change or improvement. Can someone
advise me as to how long does it take to actually
notice an improvement? Previously i was on paxil
20mg. which made me feel like a detached person
could not stand that feeling.
Reply the comment

Kevin Haren (4 years ago):

Does Pristiq have a false positive urinalysis effect for methadone.
Reply the comment

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Comments from related studies:

  • From this study (4 weeks ago):

  • Never had anything like this before taking Pristiq. It worked great for depression but after 9 months I started get more and more muscle pains and ticks in my neck. I have since quit using Pristiq, but still suffer from dystonia symptoms.


    angiepanjie on Jun, 4, 2014:

    I started taking Pristiq in 2010 - 6 months later was diagnosed with dystonia. It started out as strange sensations in my head and neck, then just my neck and shoulder pulled to the left. 3 and a half years later I am learning to live with dystonia as the symptoms have gotten worse. It is a strange coincidence these symptoms came after starting this drug, however my neurologist will not say if it was the drug or not. Regardless I have it, there is no cure, and the best thing I can do is be positive, do what I can and practice gratitude for the things I can do (took a LONG time to get to that point though, spent a long time being pretty mad!). Good luck, and bless ya'all.


  • From this study (1 month ago):

  • Have used all other meds for over 6 months. Pravastatin used for one month, then breast pain started.


  • From this study (2 months ago):

  • possible vaginal irritation and/or infection. Questionable of possibility of blisters inside folds vaginal tissue. (Not internal vaginal, just inside the folds of skin.)


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More questions for: Pristiq

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  • Stopping pristiq for my memory
    I have been on Pristiq for 3 years. My short term memory loss is a great concern to me. I am 45 and I have questioned my doctor and given my concerns to the point she referred me to a neurologist but said it was not the Pristiq. There is no other drugs I am taking or have taken to cause this proble ...

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More reviews for: Pristiq

On eHealthMe, Pristiq (desvenlafaxine succinate) is often used for depression. Find out below the conditions Pristiq is used for, how effective it is, and any alternative drugs that you can use to treat those same conditions.

What is Pristiq used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

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- Depressed mood
- Depression
- Dysthymia
- Generalized anxiety disorder
- Major depression
- Stress and anxiety


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