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Review: Pseudoephedrine side effects

In this review, we analyze Pseudoephedrine hydrochloride side effects by the time on the drug, gender and age (0-60+) of the people who have side effects while taking Pseudoephedrine hydrochloride. The review is based on 186 people who have side effects while taking Pseudoephedrine hydrochloride from FDA and social media, and is updated regularly.

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What is Pseudoephedrine hydrochloride

Pseudoephedrine hydrochloride (latest outcomes from 674 users) has active ingredients of pseudoephedrine hydrochloride. It is often used in nasal congestion.

Other drugs that have the same active ingredients (pseudoephedrine hydrochloride): Novafed, Sudafed 12 Hour, Sudafed 24 Hour, Sudafed.

On Oct, 13, 2014: 186 people who reported to have side effects when taking Pseudoephedrine hydrochloride are studied


Most common side effects over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Dizziness AggravatedIrritabilityAcneEdemaIntestinal SpasmShoulder PainLeg SwellingRectal Haemorrhage
DeathAngerTremorParanoiaShortness Of BreathDiarrheaInfusion Site Haemorrhage
DizzinessHeat IntoleranceSexual DysfunctionSleepiness - During The DayTinnitusAnxietyHaemorrhoids
AnxietyConfusional StateHeart PalpitationsChronic DepressionEncephalopathy
Menstrual Cycle ProlongedAgitationGoiterSensory LossBlood Pressure Increased
Caecum PerforationSleepinessNausea And VomitingRash FollicularBlood Creatinine Increased
TirednessDouble VisionFatigueTension HeadachesMood Swings
Bleeding TendencyAnxiety AggravatedAnxiety DisorderDrug IneffectiveHeadache
Rapid Heart BeatHypertensionFeeling JitteryNormochromic Normocytic Anaemia

Most common side effects by gender * :

Dry MouthCardiac Arrest
AgitationMultiple Drug Overdose
FatigueBody Temperature Increased
VomitingDizziness Aggravated

Most common side effects by age * :

n/aHallucinationLeukocytosisHypertensionFatigueRespiratory ArrestNauseaHaemorrhoids
Normochromic Normocytic AnaemiaTachycardiaDeathConstipationHeart Rate IncreasedRectal Haemorrhage
ProteinuriaCardiac ArrestDrug AbuseOvarian Cancer NosDrug Effect IncreasedInfusion Site Haemorrhage
HypoalbuminaemiaBody Temperature IncreasedBlood Gases AbnormalDry MouthPanic AttackFatigue
HeadacheDeliriumBlood Bicarbonate DecreasedParanoiaAspartate Aminotransferase IncreasedInfluenza Like Illness
Blood Creatinine IncreasedMultiple Drug OverdoseBlood Glucose IncreasedAgitationBlood Uric Acid IncreasedDepression Nec
Blood Pressure IncreasedNauseaCardiac Failure CongestiveSkin Lesion NosBlood Creatine IncreasedMalaise
EncephalopathyAcneCold SweatHeadache NosAbdominal Pain UpperAllergy Aggravated
VomitingRashCardiomyopathyPelvic MassAgitationAlopecia
Benign Intracranial HypertensionShiveringArrhythmiaRigorsSensory LossSedation

* Some reports may have incomplete information.

Browse Pseudoephedrine hydrochloride side effects from A to Z:

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Are you taking Pseudoephedrine hydrochloride?

Comments from related studies:

  • From this study (2 months ago):

  • I'm having oral surgery in a couple of days & dentist gave me xanax to take for the anxiety. I tried one pill Friday night to see how it would affect me & noticed the swelling Saturday


  • From this study (3 months ago):

  • If I take Sudafed for a week or more then stop the med it seems like it get laryngitis


  • From this study (3 months ago):

  • Coughing is severe often to the point that things go black and there is a ringing in my ears. I have never passed out, though I often think I may. I have allergies and my coughing onset is usually due to aspiration of food drink or sinus drainage. Sometimes It begins with a sharp tickle in my larynx.


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More questions for: Pseudoephedrine hydrochloride

You may be interested at these reviews (what is this?):

  • Skin burning sensation with delsym
    I had been sick for about a week and had been taking Sudafed every 4-6 hours for congestion for the past couple of days. I also take wellbutrin SR daily as an antidepressant. I started taking the suspension formula of Delsym 12 hour release about 24 hours previously (so I had already had two doses ...

  • Bad nosebleed (sudafed related?)
    I have the rhinitis as a result of rebound syndrome from using nasal sprays for years. I use the Flonase to somewhat alleviate the need for the over-the-counter sprays (first two drugs listed). In spite of that, I rarely, if ever, have nosebleeds. I also rarely, if ever, get colds. However, yesterda ...

More reviews for: Pseudoephedrine hydrochloride

On eHealthMe, Pseudoephedrine Hydrochloride (pseudoephedrine hydrochloride) is often used for nasal congestion. Find out below the conditions Pseudoephedrine Hydrochloride is used for, how effective it is, and any alternative drugs that you can use to treat those same conditions.

What is Pseudoephedrine Hydrochloride used for and how effective is it:

Other drugs that are used to treat the same conditions:

Studies of common Pseudoephedrine hydrochloride drug interactions:

Browse Pseudoephedrine hydrochloride drug interactions with drugs from A to Z:

NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.


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