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Review: Duspatalin side effects

In this review, we analyze Duspatalin side effects by the time on the drug, gender and age (0-60+) of the people who have side effects while taking Duspatalin. The review is based on 120 people who have side effects while taking Duspatalin from FDA and social media, and is updated regularly.

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What is Duspatalin

Duspatalin (latest outcomes from 127 users) has active ingredients of mebeverine hydrochloride. It is often used in irritable bowel syndrome.

Other drugs that have the same active ingredients (mebeverine hydrochloride): Colofac, Mebeverine Hydrochloride, Duspatal.

On Jan, 12, 2015: 120 people who reported to have side effects when taking Duspatalin are studied


Most common side effects over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Hepatic Encephalopathy (spectrum of neuropsychiatric abnormalities in patients with liver failure)Renal Failure (kidney dysfunction)n/an/aRenal Failure Acute (rapid kidney dysfunction)Hypokalaemia (low potassium)n/aDiarrhoea
Encephalopathy (functioning of the brain is affected by some agent or condition)Thrombocytopenia (decrease of platelets in blood)Systemic Inflammatory Response Syndrome (an inflammatory state affecting the whole body, frequently a response of the immune system to infection)Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)Confusional State
Urticaria (rash of round, red welts on the skin that itch intensely)Neutropenic Infection (infection with less neutrophil numbers in blood)Pyrexia (fever)Renal Failure Acute (rapid kidney dysfunction)
Anaphylactic Shock (severe and rapid and sometimes fatal hypersensitivity reaction to a substance)Metabolic Acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)Neuroleptic Malignant Syndrome (a life-threatening neurological disorder most often caused by an adverse reaction to neuroleptic or antipsychotic agents)Abdominal Pain
Hepatic Neoplasm Malignant (liver cancer)Confusional StateBronchopneumonia (inflammation of the lungs, arising in the bronchi or bronchioles)Delirium (wild excitement)
Disease ProgressionFebrile Neutropenia (fever with reduced white blood cells)Dehydration (dryness resulting from the removal of water)Pyrexia (fever)
Blood Creatine IncreasedChest PainBlood Creatine Phosphokinase IncreasedNausea (feeling of having an urge to vomit)
ConstipationDyspnoea (difficult or laboured respiration)
Blood Urea IncreasedWeight Decreased
International Normalised Ratio Increased

Most common side effects by gender * :

Confusional StateAbdominal Pain
Renal Failure Acute (rapid kidney dysfunction)Weight Decreased
DiarrhoeaPyrexia (fever)
Delirium (wild excitement)Constipation
Dyspnoea (difficult or laboured respiration)Asthenia (weakness)
Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection)
International Normalised Ratio IncreasedNausea (feeling of having an urge to vomit)
Therapeutic Response Increased (high preventive response)Flatulence (flatus expelled through the anus)
Decreased Appetite (decreased appetite occurs when you have a reduced desire to eat)Gastrointestinal Inflammation (inflammation of stomach and intestine)
Pyrexia (fever)Diarrhoea

Most common side effects by age * :

n/an/an/aChest PainHeart Rate IncreasedAgranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection)Colitis Ulcerative (inflammation of colon with ulcer)Renal Failure Acute (rapid kidney dysfunction)
Crohn's Disease (condition that causes inflammation of the gastrointestinal tract)Weight DecreasedDiarrhoeaConfusional State
Depressed Level Of ConsciousnessAbdominal PainThrombocytopenia (decrease of platelets in blood)Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
ConstipationNausea (feeling of having an urge to vomit)Myalgia (muscle pain)Delirium (wild excitement)
Headache (pain in head)Gastrointestinal Inflammation (inflammation of stomach and intestine)Gamma-glutamyltransferase IncreasedFall
Colonic Stenosis (abnormal narrowing of colon)Asthenia (weakness)Diarrhoea
Lymphadenitis Viral (viral infection of lymph node)Gene Mutation Identification Test PositiveRhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down)
General Physical Condition AbnormalSurgeryTherapeutic Response Increased (high preventive response)
Epstein-barr Virus Associated Lymphoma (epstein-barr virus associated tumour)Back PainDyspnoea (difficult or laboured respiration)
Night Sweats (sweating in night)Blood Creatinine IncreasedInternational Normalised Ratio Increased

* Some reports may have incomplete information.

Browse Duspatalin side effects from A to Z:

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Are you taking Duspatalin?

Comments from related studies:

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  • Omerprazole


  • From this study (8 months ago):

  • Go through phases of being exceptionally tired and find that I have to go to sleep during the day. At night can sleep for over 8 hours and find it hard to get up. Frequent bouts of yawning and know I need to have a sleep.


  • From this study (9 months ago):

  • I had a FNA of the thyroid nodules,I get my results next week.


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Can you answer these questions (Ask a question):

  • Can mrsa cause chronic intestinal pseudo obstruction?
    I had a small bowel obstruction caused by adhesions from an appendectomy carried out 20yrs previously and had grumbling pain ever since but been labelled a malingerer by my family GP until one day at work when I started with terrible tummy ache and sickness like I'd never known, fetching up bile with force. I hated going to hospital after yrs of being called a moaner but after a day of rolling round in pain, temperature of 103 an dehydration, my Mammy insisted we go and I was seen straight away - to my shock I was in theatre within 3hrs with a serious obstruction.
    I never really recovered... The obstruction returned after 2 days and a portion of necrotic bowel was removed, then further fever and cellulitis then MRSA and deaths door.... Isolation in high dependency (intensive care) wound break down, ventilated and all related issues that come with that - chest infection, pneumonia, bed sores. Total time in hospital 8 months. Negative pressure dressing on laparotomy wound, colostomy, picc, 4 rounds of vancomycin, minor flirt with heart failure (just water related) an eventually everything healed. Had a large incisional hernia to repair and some corrective work to the horrific scarring but then the neuropathy started plus problems eating, spewing up after any solid food, more than a few forks, diarrhoea and sickness or constipation nausea and pain driving me mad, tried all manner of drugs, nerve blocks, physio, floating tank, acupuncture, opiates, non opiates, spinal cord stimulation, an now a consultant just had a 'eureka' moment and said were you treated with vancomycin when you had MRSA? If so I'm pretty sure you have chronic intestinal pseudo obstruction and is 90% sure but wants to take a muscle biopsy to be certain. I've had so much surgery and bad news in the last 10yrs I'm terrified of germs, hospital acquired bugs and anaesthetics, is there any other way? Or can I have this test done awake - conscious sedation? I had it before during spinal cord surgery so I know what's involved and it's better than GA as I know what's going on, who is doing what to me etc...
    Does anyone with a medical background know about this ailment/disease? Does it sound feasible that MRSA or it's treatment could have caused this? I was surgically debrided up to every other day when the vac pac/negative pressure machine and dressings were changed and the doctors told me I lost a great deal of tissue and had a lot of nerve damage due to the infection.
    Any patient perspectives on this illness would also be very much valued in helping me make a decision, moving forward. If all this is going to accomplish is to attach a label to the pain but not actually change anything, after fighting it for 10yrs now, avoiding hospital as much as I can, I really can't see the point of exploratory surgerys and biopsys now when it is known that I have this propensity towards adhesions and a new wound means a potentially new adhesion growth site.
    If it helps, the appendectomy happened when I was 10yrs old, the MRSA when I was 30 and I am now 40.
    Beat Wishes.
  • My doctor ims bhu prescribe me for search constipation drug >mebeverine hydrochloride ip 200 mg indian dr reddy"s lab brand name morease sr.
  • Is there any medical study supports the long term use of mebeverine for 3 months or more ?

More questions for: Duspatalin

More reviews for: Duspatalin

On eHealthMe, Duspatalin (mebeverine hydrochloride) is often used for irritable bowel syndrome. Find out below the conditions Duspatalin is used for, how effective it is, and any alternative drugs that you can use to treat those same conditions.

What is Duspatalin used for and how effective is it:

Other drugs that are used to treat the same conditions:

Studies of common Duspatalin drug interactions:

Browse Duspatalin drug interactions with drugs from A to Z:

NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

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