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Review: Serenoa repens side effects

In this review, we analyze Serenoa repens side effects by the time on the drug, gender and age (0-60+) of the people who have side effects while taking Serenoa repens. The review is based on 88 people who have side effects while taking Serenoa repens from FDA and social media, and is updated regularly.

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What is Serenoa repens

Serenoa repens (latest outcomes from 90 users) has active ingredients of saw palmetto. It is often used in phytotherapy.

It can also be called: Saw Palmetto, American Dwarf Palm Tree, Cabbage Palm, Ju-Zhong, Palmier Nain, Sabal, Sabal Fructus, Sabal serrulata, Saw Palmetto Berry, Serenoa serrulata.

On Jan, 2, 2015: 88 people who reported to have side effects when taking Serenoa repens are studied


Most common side effects over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
General Physical Health Deterioration (weak health status)Pulmonary Haemorrhage (acute bleeding from the lung)n/an/an/an/an/aRenal Failure Acute (rapid kidney dysfunction)
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)Cardiopulmonary Failure (cessation of normal circulation of the blood due to failure of the heart to contract)Condition Aggravated
BreathlessnessUpper Gastrointestinal Haemorrhage (upper gastrointestinal bleeding)Tremor (trembling or shaking movements in one or more parts of your body)
Bronchopneumonia (inflammation of the lungs, arising in the bronchi or bronchioles)Renal Failure (kidney dysfunction)
Orchitis (inflammation of the testes)Ventricular Fibrillation (abnormally irregular heart rhythm)
Metabolic Acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)Dehydration (dryness resulting from the removal of water)
International Normalised Ratio IncreasedVentricular Tachycardia (rapid heartbeat that originates in one of the lower chambers (the ventricles) of the heart)
Platelet Count DecreasedHypotension (abnormally low blood pressure)
Loss Of ConsciousnessCardiac Failure Congestive
Respiratory Gas Exchange Disorder (gas exchange disease of respiratory system)Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)

Most common side effects by gender * :

Hypotension (abnormally low blood pressure)Renal Failure Acute (rapid kidney dysfunction)
Accidental ExposureTremor (trembling or shaking movements in one or more parts of your body)
General Physical Health Deterioration (weak health status)Condition Aggravated
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)Dehydration (dryness resulting from the removal of water)
Renal Failure (kidney dysfunction)
Ventricular Fibrillation (abnormally irregular heart rhythm)
Ventricular Tachycardia (rapid heartbeat that originates in one of the lower chambers (the ventricles) of the heart)
Cardiac Failure Congestive
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Drug Effect Decreased

Most common side effects by age * :

n/an/an/an/aLibido Decreased (loss of interest in sex)Feeling AbnormalMononucleosis Syndrome (an infection that produces flu-like symptoms, and usually goes away on its own in a few weeks)Renal Failure Acute (rapid kidney dysfunction)
Anxiety Disorder (excessive, uncontrollable, unexplained and often irrational worry)Anaemia Macrocytic (a macrocytic class of anaemia)Tremor (trembling or shaking movements in one or more parts of your body)
Electrocardiogram T Wave AbnormalCoughVentricular Fibrillation (abnormally irregular heart rhythm)
Colonic Polyp (extra part of colon tissue grow in intestine)Dehydration (dryness resulting from the removal of water)
Rectal Haemorrhage (bleeding from anus)Condition Aggravated
Asthenia (weakness)Ventricular Tachycardia (rapid heartbeat that originates in one of the lower chambers (the ventricles) of the heart)
Coagulopathy (blood's ability to clot is impaired)Hypotension (abnormally low blood pressure)
Encephalopathy (functioning of the brain is affected by some agent or condition)Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Nitrite Urine Present (nitrite in urine)Renal Failure (kidney dysfunction)
Jaundice (a yellowish pigmentation of the skin, the conjunctival membranes)Drug Toxicity

* Some reports may have incomplete information.

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Are you taking Serenoa repens?

Comments from related studies:

  • From this study (2 weeks ago):

  • Just started the drug therapy two days ago. Pain is relieved but I can still feel the effects, especially weakness.


  • From this study (2 months ago):

  • It seems to me that the anal itching began shortly after I began taking Zetia. My doctor described it as caused by a fungus and prescribed Clotrimazole topical cream. He said to apply twice daily for one month, which I did. I am now into approximately month 3-4 and the itching continues. If I apply the cream twice daily, the itching is under control, but if I don't apply the cream twice daily the itching gets severe. After I started taking Zetia, I noticed frequent stomach gas and some fluid spotting in my underwear. The gas problem is embarrassing in public because it just doesn't stop, and I will have a loose bowel movement. I feel there is a connection between this gassiness and loose bowel movement since I started taking Zetia. Is the Zetia causing a fungal problem in my stomach which is causing the anal itching?


    DrLivingston on Oct, 29, 2014:

    (48 y.o. male) it sounds like you may have SIBO (Small Intestine Bacterial Overgrowth). The test for it is very easy and relatively cheap. You need to call a gastroenterologist's office and ask if they use the hydrogen breath test to test for SIBO.

    If they don't, just keep looking until you find one who does, because if they know what SIBO is, but they don't offer that test, they'll most likely want to do an endoscopy, which is invasive, expensive, very uncomfortable (they shove a tube down your throat past your stomach into your duodenum) and take a biopsy, and it's not an accurate way to test for SIBO any way, because SIBO is generally found in the distal small intestine, which is about 12-15 feet deeper into your guts where an endoscopy can't even get CLOSE to reaching.

    Get the hydrogen breath test for SIBO. That will very likely come back positive for you. Bacterial overgrowth in the small intestine creates gas which causes abdominal bloating and gas and either diarrhea or constipation, which depends on the specific species of bacteria that has overgrown.

    You want to get this taken care of ASAP because while about 80%+ of doctors will misdiagnose it as IBS and/or Celiac, it's not and left untreated and CURED, will lead to Crohn's, misery and eventual death, but it won't be quick; it will be extremely slow and agonizing.

    Read Dr. Mark Pimentel's 'A New IBS Solution' and Dr. Elaine Gottschall's 'Breaking the Vicious Cycle'.

    BTW, I'm not a doctor, but I've been dealing with and researching SIBO for 4 years now. The scary thing is, I've heard of people who've had it for 30+ years.

    SIBO is the root cause underlying IBS, which is what both of those books discuss.


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    I'm not ready to claim that the Saw Palmetto did it but I really just don't know.
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NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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