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Review: Tizanidine side effects

In this review, we analyze Tizanidine hydrochloride side effects by the time on the drug, gender and age (0-60+) of the people who have side effects while taking Tizanidine hydrochloride. The review is based on 1,184 people who have side effects while taking Tizanidine hydrochloride from FDA and social media, and is updated regularly.

Get connected: join a mobile support group for people who have Tizanidine side effects >>>

What is Tizanidine hydrochloride

Tizanidine hydrochloride (latest outcomes from 1,521 users) has active ingredients of tizanidine hydrochloride. It is often used in muscle spasms.

Other drugs that have the same active ingredients (tizanidine hydrochloride): Zanaflex.

On Sep, 23, 2014: 1,184 people who reported to have side effects when taking Tizanidine hydrochloride are studied


Most common side effects over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
HypotensionAspartate Aminotransferase IncreasedHallucination, VisualHigh Blood PressureHypokalaemiaConvulsionDysaesthesiaPain
NauseaAlanine Aminotransferase IncreasedBlood Creatine Phosphokinase IncreasedHot FlushesHypomagnesaemiaVomitingParotitisFatigue
DizzinessDiffuse Large B-cell LymphomaAspartate Aminotransferase IncreasedRigorsNeutropeniaHyponatraemiaLow Blood PressurePyrexia
Suicide AttemptHypertoniaIntentional OverdoseBasilar MigraineFungal SepsisGastric UlcerErectile DysfunctionVomiting
PneumoniaHepatic Function AbnormalPain - HeadConstipation AggravatedConvulsionLoss Of ConsciousnessSwollen TongueNausea
TachycardiaBlood Lactate Dehydrogenase IncreasedTearfulnessBack InjuryAnaemiaHypoaesthesiaDiarrhoea
PyrexiaAnorexiaHearing LossPersonality ChangeCondition AggravatedMuscular WeaknessAbdominal Pain
Aspartate Aminotransferase IncreasedSomnolenceMissed PeriodsHair LossPericardial EffusionDisturbance In AttentionHeadache
Alanine Aminotransferase IncreasedNauseaIntervertebral Disc DegenerationPersonality Change Due To A General Medical ConditionNeutropenic SepsisEmotional DistressFall
FatigueMuscle RigidityHeadacheBlood UrineInsomniaPain In ExtremitySomnolence

Most common side effects by gender * :

Abdominal PainDepression
Oedema PeripheralDizziness

Most common side effects by age * :

Accidental ExposureNeuroleptic Malignant SyndromeCardiac DisorderCardiac ArrestFatigueNauseaPainVomiting
Rectal ProlapseCardiac DisorderVomitingVentricular FibrillationDyspnoeaPyrexiaAnaemiaHypotension
Cardio-respiratory ArrestEpstein-barr Virus InfectionTorsade De PointesSuicide AttemptHeadacheAnxietyMalaise
PneumoniaInjuryPainLoss Of ConsciousnessFallPneumoniaSomnolence
Sudden DeathHypersensitivityComaPyrexiaFatigueCoughDiarrhoea
BradyarrhythmiaAbdominal TendernessUpper Respiratory Tract InfectionSyncopeMultiple Sclerosis RelapseAbdominal PainPyrexia
SomnolenceCholecystitis ChronicSudden DeathAstheniaVomitingEmotional DistressAsthenia
AbscessDecreased AppetiteDrug IneffectiveMultiple SclerosisDizzinessDiverticulumNausea
HypotoniaFood IntoleranceDrug DependenceAltered State Of ConsciousnessBlood Pressure DecreasedHypophagiaHyperkalaemia
TremorAbdominal PainBlood Potassium DecreasedCirculatory CollapseConstipationNauseaDecreased Appetite

* Some reports may have incomplete information.

Browse Tizanidine hydrochloride side effects from A to Z:

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Are you taking Tizanidine hydrochloride?

Comments from related studies:

  • From this study (3 days ago):

  • I went to a Rheumatologist and he said I have Hashimoto disease and said its not serious enough to take meds for. The test is - Thyroid Peroxidase Antiboties - my number is 363. It says that is should be <9. I was wondering if these medications I am on could be causing abnormal reading. I do have severe inflammation due to serious injuries.


    matypoe on Aug, 28, 2014:

    Please get treated! Go to a functional medicine doctor...those antibodies are way too high, no matter what the root cause...pick up the book Stop the Thyroid Madness, as well as The Root Cause by Isabela Wentz. Also check out Mary Shomon. There are FB Support Groups as well, including Hashimoto's 411, For Thyroid Patients Only, several others to find information and support, where we are all Hashi's sufferers. Please be your own best advocate and get to the right doctor (not an endo despite what you may have been led to believe) who will actually help you! I am a long time Hashimoto's patient, trust me!


  • From this study (5 days ago):

  • I recently quit taking all meds due to loss of insurance coverage. I have been having symptoms for a week that seem to only get worse


  • From this study (1 week ago):

  • Bones in toes and fingers have changed. Swelling in fingers and toes. Numbness in hands and feet. Tingling in hands and feet. Pain in hands and feet and knees.


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More reviews for: Tizanidine hydrochloride

On eHealthMe, Tizanidine Hydrochloride (tizanidine hydrochloride) is often used for muscle spasms. Find out below the conditions Tizanidine Hydrochloride is used for, how effective it is, and any alternative drugs that you can use to treat those same conditions.

What is Tizanidine Hydrochloride used for and how effective is it:

Other drugs that are used to treat the same conditions:

Studies of common Tizanidine hydrochloride drug interactions:

Browse Tizanidine hydrochloride drug interactions with drugs from A to Z:

NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.


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