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Review: Wellbutrin xl side effects

In this review, we analyze Wellbutrin xl side effects by the time on the drug, and age (0-60+) of the people who have side effects while taking Wellbutrin xl. The review is based on 11,492 people who have side effects while taking Wellbutrin xl from FDA and social media, and is updated regularly.

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What is Wellbutrin xl

Wellbutrin xl (latest outcomes from 13,325 users) has active ingredients of bupropion hydrochloride. It is often used in depression.

Other drugs that have the same active ingredients (bupropion hydrochloride): Wellbutrin, Wellbutrin Sr, Zyban, Bupropion Hydrochloride, Forfivo Xl.

On Mar, 30, 2015: 11,492 people who reported to have side effects when taking Wellbutrin xl are studied


Most common side effects over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
NauseaDepressionInsomniaGrand Mal ConvulsionDrug IneffectiveFatigueDizzinessDepression
UrticariaConvulsionDrug IneffectiveAnxietyConvulsionDepressionHeadacheNausea
RashAnxietyConvulsionDrug IneffectiveDizzinessInsomniaFatigueAnxiety
DizzinessNauseaGrand Mal ConvulsionInsomniaFatigueBipolar DisorderDepressionPain
AnxietyGrand Mal ConvulsionHeadacheHeadacheNauseaConvulsionWeight GainDrug Ineffective
InsomniaDizzinessDepressionFeeling AbnormalAbdominal PainImpaired Driving AbilityHeadache - TensionFatigue
HeadacheDrug IneffectiveNauseaAmnesiaDepressionWeight IncreasedConstipationHeadache
PruritusInsomniaWeight DecreasedDepressionExhaustion, Fatigue, Lethargy, Tiredness, WearinessHeadacheFatigue - ChronicDyspnoea
ConvulsionHeadacheSuicidal IdeationDizzinessOedema PeripheralDry MouthNauseaBack Pain

Most common side effects by age * :

Drug Exposure Via Breast MilkConvulsionConvulsionNauseaDrug IneffectiveNauseaNauseaDrug Ineffective
AnorexiaSpeech DisorderGrand Mal ConvulsionDrug IneffectiveNauseaDrug IneffectiveDrug IneffectiveInsomnia
Maternal Drugs Affecting FoetusVomitingSuicide AttemptConvulsionDizzinessInsomniaAnxietyNausea
Grand Mal ConvulsionDysphagiaTremorRashAnxietyDizzinessDepressionDizziness
Balance DisorderLaryngomalaciaDrug IneffectiveDepressionHeadacheAnxietyHeadacheAnxiety
HypotensionPostictal StateOverdoseHeadacheDepressionHeadacheFatigueHeadache
Accidental Drug Intake By ChildAccidental OverdoseNauseaInsomniaRashDepressionInsomniaFatigue
Depressed Level Of ConsciousnessAccidental ExposureIntentional OverdoseDizzinessInsomniaFatiguePainTremor
Ventricular TachycardiaDrug Exposure During PregnancyVomitingGrand Mal ConvulsionFatigueRashDizzinessDepression
Unresponsive To StimuliGrand Mal ConvulsionRashAnxietyTremorAgitationDyspnoeaPruritus

* Some reports may have incomplete information.

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Comments for this study:

ELP814 (2 years ago):

I am a 28 year old female with a sulfa allergy. I recently was switched from Effexor Xr to Wellbutrin xl. I did fine on the half dosage during the transition process but I have been on the full 300mg dose for 2 days and I'm super itchy and seem to be breaking out in mild hives. I haven't changed anything else, used anything strange or eaten anything out of the norm. Could I be allergic to something in the Wellbutrin?
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Are you taking Wellbutrin xl?




On eHealthMe, Wellbutrin Xl (bupropion hydrochloride) is often used for depression. Find out below the conditions Wellbutrin Xl is used for, how effective it is, and any alternative drugs that you can use to treat those same conditions.

What is Wellbutrin Xl used for and how effective is it:

Other drugs that are used to treat the same conditions:

Studies of common Wellbutrin xl drug interactions:

Browse Wellbutrin xl drug interactions with drugs from A to Z:

NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.


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