eHealthMe - Personalized health information & community eHealthMe - Personalized health information & community

Personalized health information & community

  Tools   Community
All drugs: A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
All conditions: A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Check symptoms       Compare drugs       Ask question       Write review       Answered/ Unanswered       Reviews

Review: Zestoretic side effects

In this review, we analyze Zestoretic side effects by the time on the drug, gender and age (0-60+) of the people who have side effects while taking Zestoretic. The review is based on 2,542 people who have side effects while taking Zestoretic from FDA and social media, and is updated regularly.

You are not alone: join a mobile support group for people who have Zestoretic side effects >>>





What is Zestoretic

Zestoretic (latest outcomes from 2,606 users) has active ingredients of hydrochlorothiazide; lisinopril. It is often used in high blood pressure.

Other drugs that have the same active ingredients (hydrochlorothiazide; lisinopril): Prinzide, Lisinopril And Hydrochlorothiazide.

On Jan, 3, 2015: 2,542 people who reported to have side effects when taking Zestoretic are studied


Most common side effects over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe)Cardiac Failure CongestiveRenal Failure Acute (rapid kidney dysfunction)DiarrhoeaCerebrovascular Accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)Hypotension (abnormally low blood pressure)Angioedema (rapid swelling of the dermis)Pain
Diabetes Mellitus Inadequate ControlCoughSepsis (a severe blood infection that can lead to organ failure and death)Dyspnoea (difficult or laboured respiration)Headache (pain in head)Dehydration (dryness resulting from the removal of water)Toxic Skin Eruption (skin breakdown due to toxic substance)Nausea (feeling of having an urge to vomit)
Interstitial Lung DiseaseChronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe)Respiratory Failure (inadequate gas exchange by the respiratory system)Alveolitis (inflammation in the socket of a tooth)Malaise (a feeling of general discomfort or uneasiness)Syncope (loss of consciousness with an inability to maintain postural tone)Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)Hypertension (high blood pressure)
Coronary Arterial Stent InsertionDyspnoea (difficult or laboured respiration)Metabolic Acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)Eosinophilia (eosinophil count in the peripheral blood exceeds)Heart Rate IrregularSinus Tachycardia (a heart rhythm with elevated rate of impulses originating from the sinoatrial node)Breast Cancer MetastaticFatigue (feeling of tiredness)
Cytomegalovirus InfectionAtrial Fibrillation (fibrillation of the muscles of the atria of the heart)Pyrexia (fever)Blood Alkaline Phosphatase IncreasedTransient Ischaemic Attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow))Hyperkalaemia (damage to or disease of the kidney)Tongue Oedema (swelling of tongue)Injury
Bronchopneumonia (inflammation of the lungs, arising in the bronchi or bronchioles)Sepsis (a severe blood infection that can lead to organ failure and death)DiarrhoeaVomitingHypertension (high blood pressure)Shock (a life-threatening condition with symptoms like low blood pressure, weakness, shallow breathing, cold, clammy skin)Cholecystitis (infection of gallbladder)Anxiety
Bacterial InfectionDrug HypersensitivityNausea (feeling of having an urge to vomit)DizzinessTympanic Membrane Perforation (a break in continuity of ear drum)Cerebrovascular Accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)SurgeryAsthenia (weakness)
Blood Creatinine AbnormalHeart Rate IrregularVomitingRespiratory Distress (difficulty in breathing)Renal Failure (kidney dysfunction)Bronchopneumonia (inflammation of the lungs, arising in the bronchi or bronchioles)Erythema (redness of the skin)Hypotension (abnormally low blood pressure)
Loss Of ConsciousnessRenal Failure Acute (rapid kidney dysfunction)Lung Infiltration (a substance that normally includes fluid, inflammatory exudates or cells that fill a region of lung)Gastric Ulcer (stomach ulcer)Tinnitus (a ringing in the ears)Cardiac FailureCervix Erythema (cervix redness)Decreased Appetite (decreased appetite occurs when you have a reduced desire to eat)
Back PainRenal Failure (kidney dysfunction)Muscle Strain (an injury to a muscle in which the muscle fibres tear)CoughDeafnessDrug Eruption (adverse drug reaction of the skin)Spondylolisthesis (displacement of a vertebra or the vertebral column in relation to the vertebrae below)Fall

Most common side effects by gender * :

Nausea (feeling of having an urge to vomit)Drug Ineffective
Asthenia (weakness)Myocardial Infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Chest PainHypotension (abnormally low blood pressure)
Fatigue (feeling of tiredness)Pyrexia (fever)
FallRenal Failure Acute (rapid kidney dysfunction)
Hypotension (abnormally low blood pressure)Nausea (feeling of having an urge to vomit)
Hypertension (high blood pressure)Fatigue (feeling of tiredness)
Weight IncreasedHyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
Dehydration (dryness resulting from the removal of water)Coronary Artery Disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Headache (pain in head)Anaemia (lack of blood)

Most common side effects by age * :

Hypokalaemia (low potassium)n/aHepatitis Nos (inflammation of the liver)Somnolence (a state of near-sleep, a strong desire for sleep)Oedema Peripheral (superficial swelling)Hypertension (high blood pressure)Nausea (feeling of having an urge to vomit)Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
Amyotrophic Lateral Sclerosis (nervous system disease that attacks nerve cells called neurons in your brain and spinal cord)Hypotension (abnormally low blood pressure)SedationAnxietyChest PainAnxietyAsthenia (weakness)
CoughProthrombin Level DecreasedDiabetes Mellitus Inadequate ControlFluid Retention (an abnormal accumulation of fluid in the blood)Weight IncreasedDepressionNausea (feeling of having an urge to vomit)
Hypokalaemic Syndrome (serum concentration of potassium <3.5)Thrombocytopenia (decrease of platelets in blood)Diabetes Mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)PainNausea (feeling of having an urge to vomit)PainFatigue (feeling of tiredness)
Sinus Bradycardia (an unusually slow heartbeat due to heart disease)Haemoglobin DecreasedType 2 Diabetes MellitusInjuryCarpal Tunnel Syndrome (nerve compression at wrist results numbness weakness, pain , swelling)Hypotension (abnormally low blood pressure)Hypotension (abnormally low blood pressure)
Urticaria (rash of round, red welts on the skin that itch intensely)Hepatomegaly (abnormal enlargement of the liver)HypersensitivityDyspnoea Nos (difficult or laboured respiration)Drug IneffectiveChest PainMyocardial Infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Melaena (the passage of black, tarry stools)Dermatitis Nos (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)Subclavian Vein Thrombosis (abnormal condition in which a clot develops within the subclavian or axillary vein)Dysphagia (condition in which swallowing is difficult or painful)DepressionGastrooesophageal Reflux Disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)Pyrexia (fever)
Throat IrritationCoagulation Factor V Level DecreasedPainPlatelet Count DecreasedConstipationAnaemia (lack of blood)Fall
Pancreatitis Acute (sudden inflammation of pancreas)Cerebral Oedema (swelling of brain)Thrombosis (formation of a blood clot inside a blood vessel)Pulmonary Embolism (blockage of the main artery of the lung)Renal Failure (kidney dysfunction)DiarrhoeaDrug Ineffective
Respiratory Failure (inadequate gas exchange by the respiratory system)Convulsions Nos (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled of muscles contract and relax rapidly and repeatedly)Affective Disorder (mental disorder)Deep Vein Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)Fatigue (feeling of tiredness)FallRenal Failure Acute (rapid kidney dysfunction)

* Some reports may have incomplete information.

Browse Zestoretic side effects from A to Z:

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Are you taking Zestoretic?

Comments from related studies:

  • From this study (2 months ago):

  • Generally happens every couple of mnths has now moved to mnthly and las two episodes were within 2 weeks of each other. Oct 12-13& oct31-nov 1. I believe pain to be mittleschmirtz the hot flashes and vomiting just started within the last year.


  • From this study (3 months ago):

  • lips have been sort of numb and eyes feel like they are abut to fall out of my head. My face is red and skin is dry and itchy. Gaining weight and have lowered calories to 300 per day and increased water to one and a half gallons a day.


  • From this study (3 months ago):

  • Started using omeprazole 2 months ago. Just noticed skipped heartbeats. 1-2 per minute.


Post a new comment    OR    Read more comments

Can you answer these questions (Ask a question):

More questions for: Zestoretic

You may be interested at these reviews (Write a review):

  • Teatical adnoma was told i had testicular cancer until doctor said i did not
    I was told by a Doctor that I had Testicula cancer and he set up surgery right away. I was preped and ready to go into the surgery room and I had to ask my surgen a quick question regarding the surgery he called it an orchietomy and I asked him so you are going to cut me open and remove the Tumor ? He said nonono you have cancer untill I tell you you do not and said he was going to (LOP) cut the testicaal off and get rid of the tumor. I went nuts and said no way not my testical no no no it is my cancer and I will not remove my Testical. He saw how up set I was and said you are not ready for this today mybe at the end of the week and let me off the table right then and there. No way I was going to have my balls cut off not now or ever. I will make this Quick my girlfriend was sick over my disision she know what was going to happen to me since she worked for a group of Urologest and went to one of her doctors and told him. Out of the goodness of his heart he agreed to put me under and take a biopcy of the Tumor and as I was under have some one run and I mean run it to the Lab and see what kind of cancer it was and Guess what it was an adnoma and he removed just the tumer and what ever margin was needed and YES I have my BALLS and am very happy so you see say all you want but there are some great Doctors in Las Vegas. But I just had to Try I would of never of handled my ball loped off no way. But found out that if it was cancer my girlfriend was going to sign the paper to have the Doctor do what he had to do. Butt they had me under. LOL But I am very attached to my balls and would never beable to make that disision. Thanks you all Had to share that. Would love to know if it was from somthing I did scary. Good Luck to all of you wit this bad scar.
  • Cymbalta and pulmonary embolisms (2 responses)
    I started taking Cymbalta in August for pain. By September I was suffering from shortness of breath. Visited Doctors asking if Cymbalta could be the cause. Answer was no. By the end of September I was no longer taking Cymbalta but still suffering from shortness of breath. It was getting severe although only when I was up and moving. On Oct 10th I was admitted to the hospital. I had a myriad of tests on my heart such as stress test, echocardiogram,sonograms on my neck and legs. All were clear. Blood test indicated clots(I guess) and a cat scan was done. Both of my lungs were covered in clots. Cat scan done of my stomach,intestines etc. Doctors could find no where of origin for the clots. I am convinced it was the Cymbalta. I was taken off Celebrex when I left the hospital. I have since been taken off glimepiride,fish oil. I currently only take Lisinopril and Hydrocholorthiazide, metformin,crestor AND COUMADIN. I am providing this information as I feel it is important to others like me.

More reviews for: Zestoretic

On eHealthMe, Zestoretic (hydrochlorothiazide; lisinopril) is often used for high blood pressure. Find out below the conditions Zestoretic is used for, how effective it is, and any alternative drugs that you can use to treat those same conditions.

What is Zestoretic used for and how effective is it:

Other drugs that are used to treat the same conditions:

Studies of common Zestoretic drug interactions:

Browse Zestoretic drug interactions with drugs from A to Z:

NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.


About - Terms of service - Privacy policy - Press - Testimonials - Contact us

© 2015 All rights reserved. Use of this site constitutes acceptance of's terms of service and privacy policy.