Toprol-Xl Vs. Zoloft for a female patient aged 35 - from FDA reports

This is a personalized comparison Toprol-Xl, Zoloft for a woman aged 35. The study is created by eHealthMe based on reports from FDA.

How to use this study: bring a copy to your health teams to ensure drug risks and benefits are fully discussed and understood.

Who is eHealthMe: we are a data analysis company who specializes in health care industry. Our original studies have been referenced on 500+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and EANO. On eHealthMe, you can research drugs and monitor them (see testimonials). If you find eHealthMe useful, please help us to spread the words below or leave us a testimonial.

On Jul, 28, 2018

14,236 females aged 35 (±5) who take Toprol-Xl, Zoloft are studied.

Number of reports submitted per year:

Toprol-Xl, Zoloft for a female patient aged 35.

Information of the patient in this study:

  • Age: 35
  • Gender: female
  • Reason for the study: Anxiety And Stress

Drugs in this study:

  • Toprol-Xl (metoprolol succinate)
  • Zoloft (sertraline hydrochloride)

eHealthMe real world results for females aged 35 (±5):

Comparison with the specified adverse outcomes:
Outcome and its % of total reports:

  • Toprol-Xl: 2.21 %
  • Zoloft: 6.87 %
Tremor (trembling or shaking movements in one or more parts of your body):
  • Toprol-Xl: 0.37 %
  • Zoloft: 2.47 %

Most common side effects:

  1. Pain
  2. Nausea (feeling of having an urge to vomit)
  3. Chest Pain
  4. Breathing Difficulty
  5. Fatigue (feeling of tiredness)
  6. Abdominal Pain
  7. Dizziness
  8. Weakness
  9. Headache (pain in head)
  10. Pulmonary Embolism (blockage of the main artery of the lung)
  1. Nausea (feeling of having an urge to vomit)
  2. Fatigue (feeling of tiredness)
  3. Headache (pain in head)
  4. Pain
  5. Dizziness
  6. Drug Ineffective
  7. Weakness
  8. Insomnia (sleeplessness)
  9. Chest Pain
  10. Nausea And Vomiting

Most common side effects experienced by people in long term use:

  1. Pain
  2. Pulmonary Embolism (blockage of the main artery of the lung)
  3. Emotional Distress
  4. Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
  5. Abdominal Pain
  6. Injury
  7. Gallstones (stone formation by bile component)
  8. Cholecystitis Chronic (long lasting infection of gallbladder)
  9. Hair Loss
  10. Thrombosis (formation of a blood clot inside a blood vessel)
  1. Dizziness
  2. Drug Withdrawal Syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
  3. Pulmonary Embolism (blockage of the main artery of the lung)
  4. Nausea (feeling of having an urge to vomit)
  5. Pain
  6. Headache (pain in head)
  7. Feeling Abnormal
  8. Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
  9. Breathing Difficulty
  10. Agitation (state of anxiety or nervous excitement)

FDA reports used in this study

What are the drugs?

What are the symptoms?

Related studies:

Related publications that referenced our studies

Recent updates

Recent general studies
Recent personal studies

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

Submit your testimonial

  • Please fill in your Testimonial.
  • Please enter a minimum of 10 characters for your Testimonial.
  • Please fill in your Name.

Please wait...


Thank you!