Cannot sleep and Restless leg syndrome
Summary:
Restless leg syndrome is found among people with Cannot sleep, especially for people who are female, 60+ old.
The study analyzes which people have Restless leg syndrome with Cannot sleep. It is created by eHealthMe based on reports of 485 people who have Cannot sleep from the Food and Drug Administration (FDA), and is updated regularly. You can use the study as a second opinion to make health care decisions.
Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.
485 people who have Cannot Sleep and Restless Leg Syndrome are studied.
What is Cannot sleep?
Cannot sleep is found to be associated with 4,533 drugs and 5,059 conditions by eHealthMe.
What is Restless leg syndrome?
Restless leg syndrome (a powerful urge to move your legs) is found to be associated with 2,312 drugs and 1,739 conditions by eHealthMe.
Number of Restless leg syndrome in Cannot sleep reports submitted per year:

Gender of people who have Cannot sleep and experienced Restless leg syndrome *:
Age of people who have Cannot sleep and experienced Restless leg syndrome *:
Common co-existing conditions for these people *:
Common drugs taken by these people *:
Common symptoms for these people *:
* Approximation only. Some reports may have incomplete information.
Do you take medications and have Restless leg syndrome?
Check whether Restless leg syndrome is associated with a drug or a conditionHow to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Related studies
Treatments, associated drugs and conditions:
- Cannot sleep (360,345 reports)
- Restless leg syndrome (41,962 reports)
COVID vaccines that are related to Restless leg syndrome:
- Restless leg syndrome in Moderna COVID Vaccine
- Restless leg syndrome in Pfizer BioNTech Covid Vaccine
- Restless leg syndrome in Johnson and Johnson Covid Vaccine
Common drugs associated with Restless leg syndrome:
- Abilify: 423 reports
- Acetaminophen: 153 reports
- Acetylsalicylic acid: 221 reports
- Aciphex: 105 reports
- Actemra: 124 reports
- Actonel: 106 reports
- Adderall: 252 reports
- Advair diskus 100/50: 132 reports
- Advair hfa: 109 reports
- Advil: 120 reports
- Albuterol: 340 reports
- Albuterol sulfate: 102 reports
- Alendronate sodium: 277 reports
- Aleve: 108 reports
- Allegra: 182 reports
- Allopurinol: 205 reports
- Alprazolam: 219 reports
- Ambien: 476 reports
- Amlodipine: 283 reports
- Amoxicillin: 151 reports
- Ampyra: 148 reports
- Aredia: 183 reports
- Aripiprazole: 157 reports
- Aspirin: 900 reports
- Atenolol: 281 reports
- Ativan: 327 reports
- Atrovent: 113 reports
- Aubagio: 107 reports
- Avonex: 268 reports
- Baclofen: 246 reports
- Benadryl: 280 reports
- Calcium: 263 reports
- Carvedilol: 127 reports
- Celebrex: 340 reports
- Celexa: 214 reports
- Chantix: 180 reports
- Claritin: 178 reports
- Clonazepam: 679 reports
- Clonidine: 124 reports
- Clopra: 842 reports
- Codeine: 121 reports
- Colace: 159 reports
- Coumadin: 359 reports
- Cozaar: 119 reports
- Crestor: 321 reports
- Crysvita: 243 reports
- Cymbalta: 754 reports
- Decadron: 101 reports
- Depakote: 154 reports
- Diazepam: 307 reports
- Dilaudid: 103 reports
- Diovan: 171 reports
- Diphen: 149 reports
- Doxycycline: 143 reports
- Duragesic: 152 reports
- Duragesic-100: 104 reports
- Effexor: 485 reports
- Effexor xr: 155 reports
- Elavil: 102 reports
- Eliquis: 112 reports
- Enbrel: 301 reports
- Escitalopram: 198 reports
- Fentanyl: 182 reports
- Fish oil: 247 reports
- Flexeril: 194 reports
- Flomax: 111 reports
- Flonase: 217 reports
- Fluoxetine: 355 reports
- Folic acid: 153 reports
- Forteo: 217 reports
- Fosamax: 892 reports
- Furosemide: 423 reports
- Gabapentin: 882 reports
- Geodon: 116 reports
- Gilenya: 266 reports
- Humalog: 131 reports
- Humira: 424 reports
- Hydramine: 149 reports
- Hydrochlorothiazide: 383 reports
- Hydrocodone bitartrate and acetaminophen: 111 reports
- Ibu: 470 reports
- Ibuprofen: 427 reports
- Klonopin: 384 reports
- Klor-con: 106 reports
- Lamictal: 213 reports
- Lamotrigine: 143 reports
- Lansoprazole: 137 reports
- Lantus: 171 reports
- Lasix: 450 reports
- Latuda: 145 reports
- Levaquin: 166 reports
- Levothyroxine sodium: 214 reports
- Lexapro: 387 reports
- Lipitor: 574 reports
- Lisinopril: 571 reports
- Lopurin: 205 reports
- Loratadine: 135 reports
- Loraz: 497 reports
- Lorazepam: 446 reports
- Lortab: 196 reports
- Losartan: 203 reports
- Lunesta: 105 reports
- Lyrica: 829 reports
- Magnesium: 271 reports
- Melatonin: 223 reports
- Meloxicam: 166 reports
- Metformin: 510 reports
- Methotrexate: 384 reports
- Metoclopramide: 840 reports
- Metoclopramide hydrochloride: 178 reports
- Metoprolol tartrate: 150 reports
- Miralax: 125 reports
- Mirapex: 495 reports
- Mirtazapine: 548 reports
- Modafinil: 143 reports
- Morphine: 331 reports
- Motrin: 102 reports
- Multivitamin: 177 reports
- Naproxen: 101 reports
- Nasonex: 113 reports
- Neupro: 213 reports
- Neurontin: 477 reports
- Nexium: 458 reports
- Norco: 147 reports
- Norvasc: 224 reports
- Nuvigil: 158 reports
- Olanzapine: 144 reports
- Omeprazole: 712 reports
- Ondansetron: 145 reports
- Opsumit: 121 reports
- Oxycodone: 253 reports
- Oxycontin: 286 reports
- Pantoprazole: 299 reports
- Paracetamol: 137 reports
- Paroxetine: 220 reports
- Paxil: 267 reports
- Pepcid: 139 reports
- Percocet: 311 reports
- Phenergan: 126 reports
- Plaquenil: 146 reports
- Plavix: 210 reports
- Potassium: 113 reports
- Prednisone: 595 reports
- Pregabalin: 133 reports
- Premarin: 207 reports
- Prevacid: 214 reports
- Prilosec: 387 reports
- Profen: 427 reports
- Promethazine: 108 reports
- Protonix: 272 reports
- Provigil: 134 reports
- Prozac: 329 reports
- Pulmicort: 119 reports
- Quetiapine fumarate: 115 reports
- Ramipril: 164 reports
- Ranitidine: 183 reports
- Reglan: 362 reports
- Remicade: 108 reports
- Requip: 803 reports
- Restoril: 102 reports
- Revlimid: 195 reports
- Risperdal: 212 reports
- Ritalin: 122 reports
- Saphris: 108 reports
- Seroquel: 678 reports
- Sertraline: 425 reports
- Simvastatin: 356 reports
- Sinemet: 170 reports
- Singulair: 327 reports
- Spiriva: 232 reports
- Spironolactone: 182 reports
- Suboxone: 117 reports
- Symbicort: 158 reports
- Synthroid: 574 reports
- Tecfidera: 114 reports
- Temaz: 141 reports
- Temazepam: 141 reports
- Topamax: 182 reports
- Topiramate: 102 reports
- Toprol-xl: 115 reports
- Tramadol: 591 reports
- Tylenol: 417 reports
- Tysabri: 196 reports
- Ultram: 125 reports
- Valium: 197 reports
- Vicodin: 248 reports
- Vioxx: 314 reports
- Vitamin b12: 285 reports
- Vitamin c: 186 reports
- Vitamin d: 515 reports
- Vitamin d3: 249 reports
- Vitamins: 252 reports
- Vivitrol: 111 reports
- Wellbutrin: 403 reports
- Xanax: 478 reports
- Xeljanz: 103 reports
- Xtandi: 198 reports
- Xyrem: 831 reports
- Zantac: 208 reports
- Zetia: 121 reports
- Zide: 384 reports
- Zocor: 235 reports
- Zofran: 237 reports
- Zoloft: 437 reports
- Zolpidem: 230 reports
- Zometa: 268 reports
- Zopiclone: 193 reports
- Zyprexa: 158 reports
- Zyrtec: 237 reports
All the drugs that are associated with Restless leg syndrome:
- Restless leg syndrome (2,312 drugs)
Common conditions associated with Restless leg syndrome:
- Acid reflux: 450 reports
- Acupuncture and pain: 549 reports
- Adult hypothyroidism: 246 reports
- Alternative medicine - pain relief: 976 reports
- Antidepressant therapy: 1,489 reports
- Anxiety: 707 reports
- Anxiety aggravated: 707 reports
- Anxiety and stress: 707 reports
- Anxiety, apprehension, feeling uptight, jitters, stress, stress and anxiety, tension: 707 reports
- Apprehension: 707 reports
- Arthritis: 232 reports
- Arthritis - rheumatoid: 661 reports
- Asthma: 305 reports
- Back pain: 234 reports
- Back pain - nonspecific: 234 reports
- Bipolar: 496 reports
- Bi-polar: 496 reports
- Bipolar 1: 108 reports
- Bipolar disorder: 496 reports
- Blood cholesterol abnormal: 618 reports
- Blood cholesterol increased: 618 reports
- Blood pressure abnormal: 187 reports
- Blood pressure - high: 777 reports
- Blood pressure increased: 701 reports
- Blood triglycerides abnormal: 618 reports
- Blood triglycerides increased: 618 reports
- Bronchial asthma: 298 reports
- Cancer - prostate: 192 reports
- Cannot sleep: 485 reports
- Can't sleep: 456 reports
- Cardiac disorder: 124 reports
- Cataplexy: 315 reports
- Cessation of smoking: 146 reports
- Chronic asthma: 298 reports
- Chronic obstructive airway disease: 108 reports
- Chronic obstructive pulmonary disease: 108 reports
- Copd: 108 reports
- Crohns: 178 reports
- Crohn's disease: 178 reports
- Crohns disease: 178 reports
- Crohn's disease aggravated: 178 reports
- Daytime sleep disorder: 660 reports
- Depression: 1,489 reports
- Depression aggravated: 1,489 reports
- Depression - major: 229 reports
- Diabetes: 254 reports
- Diabetes mellitus: 255 reports
- Diabetes mellitus management: 270 reports
- Diabetes - type 2: 150 reports
- Diabetic type 2: 150 reports
- Dm: 254 reports
- Drug dependence: 143 reports
- Dyslipidemia: 660 reports
- Dyspepsia: 140 reports
- Dyssomnia: 456 reports
- Excessive sleepiness: 400 reports
- Exercise-induced asthma: 298 reports
- Familial primary pulmonary hypertension: 257 reports
- Feeling uptight: 707 reports
- Fibromyalgia: 341 reports
- Fibromyalgia syndrome: 341 reports
- Fibromyositis: 341 reports
- Fibrositis: 341 reports
- Gastroesophageal reflux disease: 450 reports
- Gastro-oesophageal reflux disease: 420 reports
- Gastrooesophageal reflux disease: 450 reports
- Gerd: 420 reports
- Gerds: 420 reports
- Glucose test: 204 reports
- Granulomatous ileocolitis: 178 reports
- Hbp: 701 reports
- Headache: 107 reports
- Headaches: 113 reports
- Heartburn: 424 reports
- Heartburn - chronic: 450 reports
- Hepatitis c: 119 reports
- High blood cholesterol: 618 reports
- High blood cholesterol and triglycerides: 618 reports
- High blood pressure: 701 reports
- High cholesterol: 618 reports
- Htn: 701 reports
- Hypercholesterolaemia: 618 reports
- Hypercholesterolemia: 618 reports
- Hyperlipidemia: 660 reports
- Hyperlipoproteinemia: 618 reports
- Hypertension: 703 reports
- Hypertension aggravated: 703 reports
- Hypothyroid: 240 reports
- Hypothyroidism: 240 reports
- Hypothyroids: 240 reports
- Hypothyroidy: 240 reports
- Inability to sleep: 456 reports
- Indigestion: 140 reports
- Inflammatory bowel disease - crohn's disease: 178 reports
- Insomnia: 456 reports
- Insomnia concerns: 485 reports
- Insomnia exacerbated: 456 reports
- Insomnolence: 456 reports
- Jitters: 707 reports
- Joint inflammation: 222 reports
- Ldl/hdl ratio increased: 618 reports
- Lipid disorders: 660 reports
- Lipid test: 618 reports
- Lipoprotein test: 618 reports
- Lower cholesterol: 472 reports
- Low thyroid: 240 reports
- Major depression: 245 reports
- Major depressive disorder: 230 reports
- Migraine: 235 reports
- Migraines: 235 reports
- Ms: 1,014 reports
- Ms hug: 1,014 reports
- Multiple myeloma: 200 reports
- Multiple sclerosis: 1,014 reports
- Muscle spasm: 234 reports
- Muscle spasms: 234 reports
- Myofascial pain syndrome: 341 reports
- Myxedema: 246 reports
- Narcolepsy: 660 reports
- Nausea: 181 reports
- Nerve pain: 191 reports
- Neuralgia: 191 reports
- Neuropathy peripheral: 163 reports
- Niddm: 150 reports
- Nocturnal myoclonus: 1,066 reports
- Non-cardiac chest pain: 420 reports
- Osteopenia: 295 reports
- Osteoporosis: 948 reports
- Pain: 909 reports
- Pain management: 907 reports
- Pain relief: 907 reports
- Panic attack: 122 reports
- Panic attacks: 122 reports
- Panic disorder: 122 reports
- Paralysis agitans: 355 reports
- Parkinson: 115 reports
- Parkinsonism: 355 reports
- Parkinsons: 115 reports
- Parkinson's disease: 356 reports
- Parkinson's disease aggravated: 356 reports
- Periodic limb movement disorder: 1,066 reports
- Plaque psoriasis: 153 reports
- Plasma cell myeloma: 200 reports
- Plmd: 1,066 reports
- Postherpetic neuralgia: 191 reports
- Post traumatic stress disorder: 128 reports
- Post-traumatic stress disorder: 107 reports
- Primary pulmonary hypertension: 257 reports
- Prostate cancer: 192 reports
- Psoriasis: 153 reports
- Psoriasis aggravated: 153 reports
- Psoriatic arthropathy: 139 reports
- Psoriatic arthropathy aggravated: 139 reports
- Psychotic disorder: 117 reports
- Ptsd: 128 reports
- Pulmonary arterial hypertension: 257 reports
- Pulmonary hypertension: 103 reports
- Pyrosis: 420 reports
- Quit smoking: 146 reports
- Ra: 661 reports
- Reduce cholesterol: 571 reports
- Reflux: 450 reports
- Reflux esophagitis: 420 reports
- Regional enteritis: 178 reports
- Restless leg: 1,513 reports
- Restless legs: 1,450 reports
- Restless legs syndrome: 1,450 reports
- Restless leg syndrome: 1,450 reports
- Rheumatoid arthritis: 661 reports
- Rls: 1,513 reports
- Schizophrenia: 193 reports
- Sleep aid: 456 reports
- Sleep disorder: 400 reports
- Sleep disorder due to a general medical condition: 400 reports
- Sleep disorder due to general medical condition, insomnia type: 400 reports
- Sleep disorder therapy: 400 reports
- Sleeping: 485 reports
- Sleeping difficulty: 456 reports
- Sleep issues: 456 reports
- Sleeplessness: 485 reports
- Sleep - too much: 400 reports
- Smoker: 146 reports
- Smoking and smokeless tobacco: 146 reports
- Smoking cessation: 146 reports
- Smoking cessation therapy: 146 reports
- Stomach upset: 140 reports
- Stop smoking: 146 reports
- Stress: 707 reports
- Stress and anxiety: 707 reports
- Tension: 707 reports
- Thin bones: 908 reports
- Thyroid: 119 reports
- Thyroid diseases: 153 reports
- Thyroid disorder: 153 reports
- Thyroide: 149 reports
- Thyroid function test abnormal: 149 reports
- Tobacco abuse: 146 reports
- Tobacco user: 146 reports
- Type 2 diabetes: 150 reports
- Type 2 diabetes mellitus: 150 reports
- Underactive thyroid: 240 reports
- Under active thyroids: 240 reports
- Unipolar depression: 229 reports
- Wakefulness: 456 reports
All the conditions that are associated with Restless leg syndrome:
- Restless leg syndrome (1,739 conditions)
How the study uses the data?
The study is based on Restless leg syndrome and Cannot sleep, and their synonyms.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
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