Narcolepsy and Personality change - from FDA reports

Personality change is found among people with Narcolepsy, especially for people who are female, 40-49 old, take medication Xyrem and have Cataplexy. This study is created by eHealthMe based on reports of 47 people who have Narcolepsy from FDA, and is updated regularly.

Who is eHealthMe: we are a data analysis company who specializes in health care industry. Our independent and original studies have been referenced on 400+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and EANO.

On Aug, 10, 2018

47 people who have Narcolepsy and Personality Change are studied.

Number of reports submitted per year:

Would you have Personality change when you have Narcolepsy?

Gender of people who have Narcolepsy and experience Personality Change *:

  • female: 63.83 %
  • male: 36.17 %

Age of people who have Narcolepsy and experience Personality Change *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 15.38 %
  • 20-29: 15.38 %
  • 30-39: 15.38 %
  • 40-49: 30.77 %
  • 50-59: 15.38 %
  • 60+: 7.69 %

Top co-existing conditions for these people *:

  1. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 14 people, 29.79%
  2. Bipolar Disorder (mood disorder): 6 people, 12.77%
  3. Stress And Anxiety: 3 people, 6.38%
  4. Restless Leg Syndrome (a powerful urge to move your legs): 3 people, 6.38%
  5. High Blood Cholesterol: 3 people, 6.38%
Check whether a drug or a condition causes Personality change

Most common drugs for these people *:

  1. Xyrem: 32 people, 68.09%
  2. Provigil: 13 people, 27.66%
  3. Nuvigil: 11 people, 23.40%
  4. Adderall: 8 people, 17.02%
  5. Topamax: 7 people, 14.89%
Check whether a drug or a condition causes Personality change

Top symptoms for these people *:

  1. Depression: 8 people, 17.02%
  2. Stress And Anxiety: 8 people, 17.02%
  3. Nausea (feeling of having an urge to vomit): 5 people, 10.64%
  4. Fatigue (feeling of tiredness): 5 people, 10.64%
  5. Mania (a state of abnormally elevated or irritable mood): 5 people, 10.64%
Click here to get more results

* Approximation only. Some reports may have incomplete information.

Are you new to Narcolepsy or have questions?

Volunteer or get paid to help people with your care experience

Related studies


Narcolepsy (brain's inability to regulate sleep-wake cycles normally) can be treated by Provigil, Nuvigil, Adderall, Xyrem, Modafinil (latest reports from 35,937 Narcolepsy patients)

Personality Change

Personality change has been reported by people with depression, quit smoking, multiple sclerosis, stress and anxiety, attention deficit hyperactivity disorder (latest reports from 7,156 Personality change patients).

Drugs that are associated with Personality change
Personality change (1,130 drugs)
Other conditions that could cause Personality change
Personality change (801 conditions)
Browse all symptoms of Narcolepsy
a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies

You are not alone. Join our personalized support groups:

You may be interested in these posts

More posts for: Narcolepsy, Personality change

Recent updates

General studies
Active Support Groups
Recent Care Guides

You could also:

  • Print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.