Abilify and Xigduo xr drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among 9 people who take Abilify and Xigduo xr. Common interactions include diabetic ketoacidotic hyperglycaemic coma among females, and anxiety among males.
The phase IV clinical study analyzes what interactions people who take Abilify and Xigduo xr have. It is created by eHealthMe based on reports from the FDA, and is updated regularly. You may use the study as a second opinion to make health care decisions.
What are phase IV trials?
Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 700+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.
9 people who take Abilify and Xigduo xr together, and have interactions are studied.
What is Abilify?
Abilify has active ingredients of aripiprazole. It is used in depression. Currently, eHealthMe is studying from 98,584 Abilify users.
What is Xigduo xr?
Xigduo xr has active ingredients of dapagliflozin propanediol; metformin hydrochloride. Currently, eHealthMe is studying from 2,589 Xigduo xr users.
Number of Abilify and Xigduo xr reports submitted per year:

Common Abilify and Xigduo Xr drug interactions by gender *:
female:
- Diabetic ketoacidotic hyperglycaemic coma
- Anxiety
- Decreased appetite
- Diabetes mellitus
- Sleep apnoea syndrome
- Weight decreased
- Diabetic foot
- Fungal infection
- Pneumonia
male:
- Anxiety
- Anhedonia
- Osteonecrosis
- Bone density decreased
- Chronic kidney disease
- Emotional distress
- Hip arthroplasty
- Multiple fractures
- Nephropathy
- Pain
Common Abilify and Xigduo Xr drug interactions by age *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Anxiety
30-39:
n/a
40-49:
n/a
50-59:
n/a
60+:
- Anhedonia
- Anxiety
- Renal impairment
- Osteonecrosis
- Pneumonia
- Bone density decreased
- Chronic kidney disease
- Diabetic ketoacidotic hyperglycaemic coma
- Emotional distress
- Hip arthroplasty
* Approximation only. Some reports may have incomplete information.
Do you take Abilify and Xigduo xr?
Personalize this study to your gender and ageHow to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Related publications that referenced our studies
- Cetin, M., Celik, M., Cakici, M., Polat, M., & Suner, A, "Aripiprazole-Induced Hoarseness", Turk Psikiyatri Dergisi, 2018 Jan .
- Cetin M, Celik M, Cakici M, Polat M, Suner A, "Aripiprazole induced non-cardiogenic pulmonary edema: a case report", Turk Psikiyatri Dergisi, 2014 Dec .
Related studies
Alternative drugs to, pros and cons of the 2 drugs:
Common Abilify side effects:
- Weight increased: 6,809 reports
- Stress and anxiety: 5,096 reports
- Drug ineffective: 4,877 reports
- Depression: 3,566 reports
- Fatigue (feeling of tiredness): 3,524 reports
- Suicidal ideation: 3,504 reports
- Insomnia (sleeplessness): 3,232 reports
Browse all side effects of Abilify:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Xigduo xr side effects:
- Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies): 251 reports
- Fatigue (feeling of tiredness): 149 reports
- Weight decreased: 119 reports
- High blood pressure: 116 reports
Browse all side effects of Xigduo xr:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Abilify interactions:
- Abilify and Seroquel: 7,633 reports
- Abilify and Risperdal: 5,565 reports
- Abilify and Cymbalta: 5,352 reports
- Abilify and Zyprexa: 5,157 reports
- Abilify and Wellbutrin: 4,949 reports
- Abilify and Lamictal: 4,705 reports
- Abilify and Lexapro: 3,790 reports
- Abilify and Zoloft: 3,672 reports
- Abilify and Clonazepam: 3,532 reports
- Abilify and Depakote: 3,438 reports
Browse all interactions between Abilify and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Xigduo xr interactions:
- Xigduo xr and Metformin: 335 reports
- Xigduo xr and Lisinopril: 169 reports
- Xigduo xr and Trulicity: 165 reports
- Xigduo xr and Aspirin: 162 reports
- Xigduo xr and Bydureon: 109 reports
- Xigduo xr and Farxiga: 107 reports
Browse all interactions between Xigduo xr and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on aripiprazole and dapagliflozin propanediol; metformin hydrochloride (the active ingredients of Abilify and Xigduo xr, respectively), and Abilify and Xigduo xr (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study. Patients in the study may take other drugs besides Abilify and Xigduo xr.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 700+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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