Accutane and Ponstel drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Accutane and Ponstel. Common interactions include fatigue among females.
The phase IV clinical study analyzes what interactions people who take Accutane and Ponstel have. It is created by eHealthMe based on reports of 8 people who take Accutane and Ponstel from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.
Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.
8 people who take Accutane and Ponstel together, and have interactions are studied.
What is Accutane?
Accutane has active ingredients of isotretinoin. It is often used in acne. eHealthMe is studying from 33,719 Accutane users for its effectiveness, alternative drugs and more.
What is Ponstel?
Ponstel has active ingredients of mefenamic acid. It is often used in pain. eHealthMe is studying from 448 Ponstel users for its effectiveness, alternative drugs and more.
Number of Accutane and Ponstel reports submitted per year:

Common Accutane and Ponstel drug interactions by gender *:
female:
- Fatigue
- Amenorrhoea
- Granulomatous liver disease
- Hepatocellular damage
- Immune system disorder
- Inflammatory bowel disease
- Lymphadenopathy
- Myalgia
- Nausea
- Splenomegaly
male:
n/a
Common Accutane and Ponstel drug interactions by age *:
0-1:
n/a
2-9:
n/a
10-19:
- Depression
- Fatigue
- Obsessive-compulsive disorder
20-29:
n/a
30-39:
n/a
40-49:
- Amenorrhoea
- Anorexia
- Granulomatous liver disease
- Hepatocellular damage
- Immune system disorder
- Inflammatory bowel disease
- Lymphadenopathy
- Myalgia
- Nausea
- Splenomegaly
50-59:
n/a
60+:
n/a
* Approximation only. Some reports may have incomplete information.
Do you take Accutane and Ponstel?
Personalize this study to your gender and ageHow to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Related publications that referenced our studies
- Ersoy MA, Ersoy HT, "Manic symptoms associated with isotretinoin and methylphenidate combination: a case report", Klinik Psikofarmakoloji Bülteni-Bulletin of Clinical Psychopharmacology, 2014 Sep .
Related studies
Alternative drugs to, pros and cons of the 2 drugs:
Common Accutane and Ponstel interactions:
- Fatigue (feeling of tiredness): 8 reports
- Chapped lips (cracking, fissuring, and peeling of the skin f lip): 7 reports
Browse all drug interactions of Accutane and Ponstel:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Accutane side effects:
- Depression: 9,826 reports
- Ulcerative colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 9,190 reports
- Crohn's disease (condition that causes inflammation of the gastrointestinal tract): 7,519 reports
- Stress and anxiety: 5,193 reports
- Irritable bowel syndrome: 4,848 reports
Browse all side effects of Accutane:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Accutane interactions:
- Accutane and Ortho tri-cyclen: 1,116 reports
- Accutane and Prednisone: 639 reports
- Accutane and Profen: 446 reports
- Accutane and Ibuprofen: 445 reports
- Accutane and Tylenol: 422 reports
- Accutane and Retin-a: 351 reports
- Accutane and Advil: 315 reports
- Accutane and Zoloft: 313 reports
- Accutane and Yasmin: 266 reports
- Accutane and Cleocin: 258 reports
Browse all interactions between Accutane and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on isotretinoin and mefenamic acid (the active ingredients of Accutane and Ponstel, respectively), and Accutane and Ponstel (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study. Patients in the study may take other drugs besides Accutane and Ponstel.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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